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123 Newest Publications about the topic viral diseases


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Progesterone-Based Therapy Protects Against Influenza by Promoting Lung Repair and Recovery in Females

15-Sep-2016 | Olivia J. Hall; Nathachit Limjunyawong; Meghan S. Vermillion; Dionne P. Robinson; Nicholas Wohlgemuth; Andrew Pekosz ..., PLoS Pathogens, 2016

by Olivia J. Hall, Nathachit Limjunyawong, Meghan S. Vermillion, Dionne P. Robinson, Nicholas Wohlgemuth, Andrew Pekosz, Wayne Mitzner, Sabra L. Klein Over 100 million women use progesterone therapies worldwide. Despite having immunomodulatory and repair properties, their effects on the outcome ...


MicroRNA expression profiles in patients with acute Crimean Congo Hemorrhagic Fever reveal possible adjustments to cellular pathways

24-Aug-2016 | Zekiye Cemre Demir, Aliye Bastug, Hurrem Bodur, Koray Ergunay, Aykut Ozkul, Journal of Medical Virology, 2016

ABSTRACT Several viral diseases are associated with altered microRNA (miRNA) expression, which can provide vital information about how cellular pathways respond to infection. However, the miRNA profile of Crimean Congo Hemorrhagic Fever (CCHFV) infections are not known. To address this gap, ...


Serological survey of viral diseases relating to reproductive failure among Artiodactyla in Ethiopian Camelus dromedarius

09-Jun-2016 | Simenew Keskes Melaku, Fekadu Regassa, Tesfaye Sisay Tessema, Fufa Dawo, Keisuke Oguma, Kumiko Nagayama, Hiroshi Sentsui, Microbiology and Immunology, 2016

ABSTRACT Serological surveys were performed among camels with a history of abortion in Ethiopia to investigate the presence of antibodies against viruses that infect the animals classified in Artiodactyla. A total of 120 serum samples were collected from camels in various parts of Ethiopia in ...


Two Oyster Species That Show Differential Susceptibility to Virus Infection Also Show Differential Proteomic Responses to Generic dsRNA

20-May-2016 | Muhammad Masood; David A. Raftos; Sham V. Nair, Journal of Proteome Research, 2016

Viral diseases are a significant cause of mortality and morbidity in oysters, resulting in significant economic losses. We investigated the proteomic responses of these two species of oysters to generic double-stranded RNAs (poly I:C and poly A:U). Analysis of proteomic data using isobaric tags ...


Exploiting Mucosal Immunity for Antiviral Vaccines

11-May-2016 | Akiko Iwasaki, Annual Review of Immunology, 2016

Mucosal surfaces provide a remarkably effective barrier against potentially dangerous pathogens. Therefore, enhancing mucosal immunity through vaccines—strengthening that first line of defense—holds significant promise for reducing the burden of viral diseases. The large and varied class of viral ...


Human DDX3 protein is a valuable target to develop broad spectrum antiviral agents [Medical Sciences]

10-May-2016 | Annalaura Brai; Roberta Fazi; Cristina Tintori; Claudio Zamperini; Francesca Bugli; Maurizio Sanguinetti; Egidio Sti ..., Proceedings of the National Academy of Sciences current issue, 2016

Targeting a host factor essential for the replication of different viruses but not for the cells offers a higher genetic barrier to the development of resistance, may simplify therapy regimens for coinfections, and facilitates management of emerging viral diseases. DEAD-box polypeptide 3 (DDX3) ...


Antiviral activity of Carbenoxolone disodium against dengue virus infection

08-May-2016 | Jieying Pu, Li He, Heping Xie, Siyu Wu, Yuye Li, Ping Zhang, Zhicong Yang, Xi Huang, Journal of Medical Virology, 2016

Abstract As one of the most important mosquito‐borne viral diseases, dengue infection is now becoming a global concern due to its rapid spread and rise in incidence. Currently, there is no approved vaccine or effective antiviral drug for dengue virus (DENV) infection. Glycyrrhetinic acid ...


Loss of CMD2‐mediated resistance to cassava mosaic disease in plants regenerated through somatic embryogenesis

10-Dec-2015 | Getu Beyene, Raj Deepika Chauhan, Henry Wagaba, Theodore Moll, Titus Alicai, Douglas Miano, James Carrington, Nigel ..., Molecular Plant Pathology, 2015

Summary Cassava mosaic disease (CMD) and cassava brown streak disease (CBSD) are the two most important viral diseases affecting cassava production in Africa. Three sources of resistance are employed to combat CMD: polygenic recessive resistance termed CMD1, the dominant monogenic type named ...


CD40 ligand‐expressing recombinant vaccinia virus (rVV40L) promotes the generation of CD8+ central memory T cells

12-Nov-2015 | Emanuele Trella, Nermin Raafat, Chantal Mengus, Emmanuel Traunecker, Valeria Governa, Swantje Heidtmann, Michael Heb ..., European Journal of Immunology, 2015

Central memory CD8+ T cells (TCM) play key roles in the protective immunity against infectious agents, cancer immunotherapy, and in adoptive treatments of malignant and viral diseases. CD8+ TCM cells are characterized by specific phenotypes, homing and proliferative capacities. However, CD8+ ...


Genome sequence of the Asian Tiger mosquito, Aedes albopictus, reveals insights into its biology, genetics, and evolution [Applied Biological Sciences]

03-Nov-2015 | Xiao-Guang Chen; Xuanting Jiang; Jinbao Gu; Meng Xu; Yang Wu; Yuhua Deng; Chi Zhang; Mariangela Bonizzoni; Wannes De ..., Proceedings of the National Academy of Sciences current issue, 2015

The Asian tiger mosquito, Aedes albopictus, is a highly successful invasive species that transmits a number of human viral diseases, including dengue and Chikungunya fevers. This species has a large genome with significant population-based size variation. The complete genome sequence was ...


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