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126 Newest Publications about the topic viral diseases

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[This Week in Science] Increasing viral threats from mosquitoes

25-Nov-2016 | Julia Fahrenkamp-Uppenbrink, Science , 2016

Epidemiology Viral diseases such as dengue, Zika, and yellow fever are transmitted by the mosquito Aedes aegypti. In a Perspective, Powell highlights recent changes in the global distribution and genetic characteristics of this insect. The two main genetic subtypes of the mosquito have ...

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Fine mapping of the RSC8 locus and expression analysis of candidate SMV resistance genes in soybean

24-Nov-2016 | Lin Zhao, Dagang Wang, Hongyun Zhang, Yingchao Shen, Yongqing Yang, Kai Li, Liqun Wang, Yunhua Yang, Haijian Zhi, Plant Breeding, 2016

Abstract Soybean mosaic disease, caused by soybean mosaic virus (SMV), is one of the most broadly distributed viral diseases of soybean (Glycine max [L.] Merr.) worldwide, which decreases seed quality and causes serious losses in yields. The accession ‘Kefeng No.1’ was previously shown to ...

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[Perspective] First flu is forever

11-Nov-2016 | Cécile Viboud; Suzanne L. Epstein, Science , 2016

Influenza is a threat that has been with humans throughout history, fueled by a constant race between host immunity and viral evolution. Control strategies rely on annual immunizations and require frequent updates of the vaccine, an expensive, cumbersome, and not always foolproof process. Efforts ...

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Progesterone-Based Therapy Protects Against Influenza by Promoting Lung Repair and Recovery in Females

15-Sep-2016 | Olivia J. Hall; Nathachit Limjunyawong; Meghan S. Vermillion; Dionne P. Robinson; Nicholas Wohlgemuth; Andrew Pekosz ..., PLoS Pathogens, 2016

by Olivia J. Hall, Nathachit Limjunyawong, Meghan S. Vermillion, Dionne P. Robinson, Nicholas Wohlgemuth, Andrew Pekosz, Wayne Mitzner, Sabra L. Klein Over 100 million women use progesterone therapies worldwide. Despite having immunomodulatory and repair properties, their effects on the outcome ...

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MicroRNA expression profiles in patients with acute Crimean Congo Hemorrhagic Fever reveal possible adjustments to cellular pathways

24-Aug-2016 | Zekiye Cemre Demir, Aliye Bastug, Hurrem Bodur, Koray Ergunay, Aykut Ozkul, Journal of Medical Virology, 2016

ABSTRACT Several viral diseases are associated with altered microRNA (miRNA) expression, which can provide vital information about how cellular pathways respond to infection. However, the miRNA profile of Crimean Congo Hemorrhagic Fever (CCHFV) infections are not known. To address this gap, ...

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Serological survey of viral diseases relating to reproductive failure among Artiodactyla in Ethiopian Camelus dromedarius

09-Jun-2016 | Simenew Keskes Melaku, Fekadu Regassa, Tesfaye Sisay Tessema, Fufa Dawo, Keisuke Oguma, Kumiko Nagayama, Hiroshi Sentsui, Microbiology and Immunology, 2016

ABSTRACT Serological surveys were performed among camels with a history of abortion in Ethiopia to investigate the presence of antibodies against viruses that infect the animals classified in Artiodactyla. A total of 120 serum samples were collected from camels in various parts of Ethiopia in ...

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Two Oyster Species That Show Differential Susceptibility to Virus Infection Also Show Differential Proteomic Responses to Generic dsRNA

20-May-2016 | Muhammad Masood; David A. Raftos; Sham V. Nair, Journal of Proteome Research, 2016

Viral diseases are a significant cause of mortality and morbidity in oysters, resulting in significant economic losses. We investigated the proteomic responses of these two species of oysters to generic double-stranded RNAs (poly I:C and poly A:U). Analysis of proteomic data using isobaric tags ...

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Exploiting Mucosal Immunity for Antiviral Vaccines

11-May-2016 | Akiko Iwasaki, Annual Review of Immunology, 2016

Mucosal surfaces provide a remarkably effective barrier against potentially dangerous pathogens. Therefore, enhancing mucosal immunity through vaccines—strengthening that first line of defense—holds significant promise for reducing the burden of viral diseases. The large and varied class of viral ...

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Human DDX3 protein is a valuable target to develop broad spectrum antiviral agents [Medical Sciences]

10-May-2016 | Annalaura Brai; Roberta Fazi; Cristina Tintori; Claudio Zamperini; Francesca Bugli; Maurizio Sanguinetti; Egidio Sti ..., Proceedings of the National Academy of Sciences current issue, 2016

Targeting a host factor essential for the replication of different viruses but not for the cells offers a higher genetic barrier to the development of resistance, may simplify therapy regimens for coinfections, and facilitates management of emerging viral diseases. DEAD-box polypeptide 3 (DDX3) ...

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Antiviral activity of Carbenoxolone disodium against dengue virus infection

08-May-2016 | Jieying Pu, Li He, Heping Xie, Siyu Wu, Yuye Li, Ping Zhang, Zhicong Yang, Xi Huang, Journal of Medical Virology, 2016

Abstract As one of the most important mosquito‐borne viral diseases, dengue infection is now becoming a global concern due to its rapid spread and rise in incidence. Currently, there is no approved vaccine or effective antiviral drug for dengue virus (DENV) infection. Glycyrrhetinic acid ...

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