10-11-2012 | Zhitao Wang, Weifeng Yao, Quanjun Deng, Xiaohui Zhang, Jianning Zhang, Journal of Molecular Neuroscience, 2012

Bone marrow stromal cells (MSCs) were used as cell therapy for various diseases in recent years. Some reports showed that transplanted MSCs promote functional recovery in animal models of brain trauma. But other studies indicate that tissue replacement by this method may not be the main ...

more

18-10-2012 | Feihui Zou, Jian Xu, Hongran Fu, Jianhua Cao, Hui Mao, Mingjie Gong, Gang Cui, Yang Zhang, Wei Shi, Jian Chen, Journal of Molecular Neuroscience, 2012

Traumatic brain injury (TBI) initiates a complex series of neurochemical and signaling changes that lead to neuronal dysfunction and over-reactive astrocytes. In our study, homeodomain interacting protein kinase 2 (HIPK2) can interact with C-terminal binding protein 2 (CtBP2) in rat brain, ...

more

11-10-2012 | Bo Ning, Zhen Li, Ningxi Zhu, Gang Hou, Qi Pang, Journal of Molecular Neuroscience, 2012

Mitogen- and stress-activated protein kinase (MSK) 1 protein was initially identified as a particularly interesting protein of mitogen-activated protein kinase. It was reported to enhance B cell lymphoma 2-associated death protein’s phosphorylation to protect cell death, suggesting that MSK1 ...

more

11-10-2012 | Yanshan Fang; Nancy M. Bonini, Annual Review of Cell and Developmental Biology, 2012

Axon degeneration is the pivotal pathological event of acute traumatic neural injury as well as many chronic neurodegenerative diseases. It is an active cellular program and yet molecularly distinct from cell death. Much effort is devoted toward understanding the nature of axon degeneration ...

more

25-09-2012 | T. Tadesse, Q. Cheng, M. Xu, D.J. Baro, L.J. Young, S.L. Pallas, Developmental Neurobiology, 2012

Abstract Retinotopic maps can undergo compression and expansion in response to changes in target size, but the mechanism underlying this compensatory process has remained a mystery. The discovery of ephrins as molecular mediators of Sperry's chemoaffinityprocessallows a mechanistic ...

more

24-09-2012 | Jian Xu, Wei Jin, Xinmin Wu, Xiaohong Wu, Aihong Li, Kaifu Ke, Jianhua Cao, Xiaojuan Liu, Xiang Tan, Hongran Fu, Yil ..., Cellular and Molecular Neurobiology, 2012

Che-1, a recently identified apoptosis related protein, affects the fate of various cell types when under stress. One attractive biological function of Che-1 is promoting the transcription of p53 after DNA damage; besides, it can also regulate cell cycle via interacting with retinoblastoma ...

more

10-09-2012 | Jian Chen, Hui Mao, HuiFei Zou, Wei Jin, Lanchun Ni, Kaifu Ke, MaoHong Cao, Wei Shi, Journal of Molecular Histology, 2012

SKIP (Ski-interacting protein), is part of nuclear regulatory complexes and interacts with factors involved in preinitiation, splicing and polyadenylation, potentiates the activity of important transcription factors, involved in an increasing number of signaling cascades. However, its ...

more

10-09-2012 | Toby B Cumming; Julie Bernhardt; Anthony J Hannan, Future Neurology, 2012

The 7th World Congress of Neurorehabilitation was held from 16–19 May, 2012, in Melbourne, Australia. Melbourne produced the largest attendance of any meeting thus far for this biennial congress of the World Federation of Neurorehabilitation. The congress provided a diverse range of ...

more

18-08-2012 | Peter S. Amenta, Jack I. Jallo, Ronald F. Tuma, Melanie B. Elliott, Journal of Neuroscience Research, 2012

Abstract After traumatic brain injury (TBI), inflammation participates in both the secondary injury cascades and the repair of the CNS, both of which are influenced by the endocannabinoid system. This study determined the effects of repeated treatment with a cannabinoid type 2 receptor ...

more

15-08-2012 | Janna L Harris, Hung-Wen Yeh, In-Young Choi, Phil Lee, Nancy E Berman, Russell H Swerdlow, Sorin C Craciunas, Willia ..., Journal of Cerebral Blood Flow & Metabolism, 2012

Altered neurochemical profile after traumatic brain injury: 1H-MRS biomarkers of pathological mechanisms Journal of Cerebral Blood Flow & Metabolism advance online publication, August 15 2012. doi:10.1038/jcbfm.2012.114 Authors: Janna L Harris, Hung-Wen Yeh, In-Young Choi, ...

more