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Erratum to: Evidence of statistical epistasis between DISC1, CIT and NDEL1 impacting risk for schizophrenia: biological validation with functional neuroimaging

01-Feb-2010 | Kristin K. Nicodemus, Joseph H. Callicott, Rachel G. Higier, Augustin Luna, Devon C. Nixon, Barbara K. Lipska, Radha ..., Human Genetics, 2010

Erratum to: Evidence of statistical epistasis between DISC1, CIT and NDEL1 impacting risk for schizophrenia: biological validation with functional neuroimaging Content Type Journal Article Category Erratum DOI 10.1007/s00439-010-0793-8 Authors Kristin K. Nicodemus, Intramural Research ...


Molecular cloning and characterization of gene encoding for cytoplasmic Hsc70 from Pennisetum glaucum may play a protective role against abiotic stresses

01-Feb-2010 | Palakolanu Sudhakar Reddy, Garladinne Mallikarjuna, Tanushri Kaul, Thammineni Chakradhar, Rabi N. Mishra, Sudhir K. ..., Molecular Genetics and Genomics, 2010

Molecular chaperones (Hsps) have been shown to facilitate protein folding or assembly under various developmental and adverse environmental conditions. The aim of this study was to unravel a possible role of heat-shock proteins in conferring abiotic stress tolerance to plants. We isolated a cDNA ...


The role of the pupal determinant broad during embryonic development of a direct-developing insect

01-Feb-2010 | Deniz F. Erezyilmaz, Melody R. Rynerson, James W. Truman, Lynn M. Riddiford, Development Genes and Evolution, 2010

Metamorphosis is one of the most common, yet dramatic of life history strategies. In insects, complete metamorphosis with morphologically distinct larval stages arose from hemimetabolous ancestors that were more direct developing. Over the past century, several ideas have emerged that suggest the ...


Modulation of gene expression in endothelial cells by hyperlipaemic postprandial serum from healthy volunteers

01-Feb-2010 | Nicolas Dejeans, Jeanette A. M. Maier, Igor Tauveron, Dragan Milenkovic, Andrzej Mazur, Genes & Nutrition, 2010

A single high-fat challenge induces plasmatic pro-inflammatory and pro-oxidative responses in the postprandial state, even in healthy men. This period is also associated with vascular endothelial dysfunction, which is an early event in the development of cardiovascular diseases. However, ...


Regulation of pro-inflammatory and pro-fibrotic factors by CCN2/CTGF in H9c2 cardiomyocytes

01-Feb-2010 | Xiaoyu Wang, Susan V. McLennan, Terri J. Allen, Stephen M. Twigg, Journal of Cell Communication and Signaling, 2010

Connective tissue growth factor (CTGF), also known as CCN2, is implicated in fibrosis through both extracellular matrix (ECM) induction and inhibition of ECM degradation. The role of CTGF in inflammation in cardiomyocytes is unknown. In some mesenchymal cell systems, CTGF mediates effects through ...


A microarray gene analysis of peripheral whole blood in normal adult male rats after long-term GH gene therapy

01-Feb-2010 | Ying Qin, Ya-Ping Tian, Cellular & Molecular Biology Letters, 2010

The main aims of this study were to determine the effects of GH gene abuse/misuse in normal animals and to discover genes that could be used as candidate biomarkers for the detection of GH gene therapy abuse/misuse in humans. We determined the global gene expression profile of peripheral whole ...


Bilberry juice modulates plasma concentration of NF-κB related inflammatory markers in subjects at increased risk of CVD

01-Feb-2010 | Anette Karlsen, Ingvild Paur, Siv K. Bøhn, Amrit K. Sakhi, Grethe I. Borge, Mauro Serafini, Iris Erlund, Petter Laak ..., European Journal of Nutrition, 2010

Purpose Bilberries are abundant in polyphenols. Dietary polyphenols have been associated with strategies for prevention and treatment of chronic inflammatory diseases. We investigated the effect of bilberry juice on serum and plasma biomarkers of inflammation and antioxidant status in subjects ...


Analysis of Nonsense-Mediated mRNA Decay by Monitoring mRNA Half-Lives in Mammalian Cells

01-Feb-2010 | Yamashita, A., Ohno, S., CSH Protocols, 2010

INTRODUCTION This protocol uses a tetracycline-response-element-regulated (Tet-Off) promoter system and Northern blotting to analyze the half-lives of premature termination codon (PTC)-containing mRNAs following the activation or suppression of the nonsense-mediated mRNA decay (NMD) pathway in ...


Description and phylogenetic relationships of a new genus of octopus, Sasakiopus (Cephalopoda: Octopodidae), from the Bering Sea, with a redescription of Sasakiopus salebrosus (Sasaki, 1920)

01-Feb-2010 | Jorgensen, Elaina M.; Strugnell, Jan M.; Allcock, A. Louise, Journal of Molluscan Studies, 2010

A new genus of octopus, Sasakiopus, is erected for the species S. salebrosus (Sasaki, 1920) n. comb. Sasakiopus salebrosus is redescribed from the holotype and from new material recently collected in the eastern Bering Sea. Molecular phylogenetic analysis of one nuclear and three mitochondrial ...


Association between AKT1 but not AKTIP genetic variants and increased risk for suicidal behavior in bipolar patients

30-Jan-2010 | L. A. V. Magno, D. M. Miranda, F. S. Neves, G. J. Pimenta, M. P. Mello, L. A. De Marco, H. Correa, M. A. Romano-Silva, Genes, Brain and Behavior, 2010

We tested the hypothesis that the presence of AKT1 and AKTIP polymorphisms, target genes that encode key proteins in the signaling of dopaminergic and serotonergic systems, is associated with suicidal behavior in bipolar patients. The subjects were 273 patients diagnosed with bipolar disorder I ...


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