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34,029 Newest Publications about the topic genes

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Two critical positions in zinc finger domains are heavily mutated in three human cancer types

28-Jun-2018 | Daniel Munro; Dario Ghersi; Mona Singh, PLoS Computational Biology, 2018

by Daniel Munro, Dario Ghersi, Mona Singh A major goal of cancer genomics is to identify somatic mutations that play a role in tumor initiation or progression. Somatic mutations within transcription factors are of particular interest, as gene expression dysregulation is widespread in cancers. ...

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Marine Drugs, Vol. 16, Pages 221: Seaweed Extract (Stella Maris®) Activates Innate Immune Responses in Arabidopsis thaliana and Protects Host against Bacterial Pathogens

28-Jun-2018 | Cook, Jamie ; Zhang, Janie ; Norrie, Jeff ; Blal, Bachar ; Cheng, Zhenyu, Marine Drugs, 2018

Marine Drugs, Vol. 16, Pages 221: Seaweed Extract (Stella Maris®) Activates Innate Immune Responses in Arabidopsis thaliana and Protects Host against Bacterial Pathogens Marine Drugs doi: 10.3390/md16070221 Authors: Jamie Cook Janie Zhang Jeff Norrie Bachar Blal Zhenyu ...

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Distribution and functional analysis of the phosphopantetheinyl transferase superfamily in Actinomycetales microorganisms [Microbiology]

26-Jun-2018 | Jeong Ho Kim; Mamoru Komatsu; Kazuo Shin-ya; Satoshi Omura; Haruo Ikeda, Proceedings of the National Academy of Sciences current issue, 2018

Actinomycetales microorganisms are a rich source of secondary metabolites, and their genomes contain many biosynthetic gene clusters for metabolites including polyketide and peptide compounds synthesized by type I polyketide synthases (PKSs) and nonribosomal peptide synthetases (NRPSs). Genes ...

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Genomic and environmental determinants and their interplay underlying phenotypic plasticity [Agricultural Sciences]

26-Jun-2018 | Xin Li; Tingting Guo; Qi Mu; Xianran Li; Jianming Yu, Proceedings of the National Academy of Sciences current issue, 2018

Integrated analysis of genotype by environment can reveal the pattern and mechanistic interplay underlying the observed phenotype dynamics. A critical question needs to be answered to enhance our ability to conduct genomic and environmental analysis of varied phenotypic plasticity observed in ...

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Viruses, Vol. 10, Pages 343: The Bacteriophage T4 MotB Protein, a DNA-Binding Protein, Improves Phage Fitness

26-Jun-2018 | Patterson-West, Jennifer ; Arroyo-Mendoza, Melissa ; Hsieh, Meng-Lun ; Harrison, Danielle ; Walker, Morgan M.; Knip ..., Viruses, 2018

Viruses, Vol. 10, Pages 343: The Bacteriophage T4 MotB Protein, a DNA-Binding Protein, Improves Phage Fitness Viruses doi: 10.3390/v10070343 Authors: Jennifer Patterson-West Melissa Arroyo-Mendoza Meng-Lun Hsieh Danielle Harrison Morgan M. Walker Leslie Knipling Deborah M. ...

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Inositol polyphosphates regulate and predict yeast pseudohyphal growth phenotypes

25-Jun-2018 | Kaitlyn L. Norman; Christian A. Shively; Amberlene J. De La Rocha; Nebibe Mutlu; Sukanya Basu; Paul J. Cullen; Anuj ..., PLoS Genetics, 2018

by Kaitlyn L. Norman, Christian A. Shively, Amberlene J. De La Rocha, Nebibe Mutlu, Sukanya Basu, Paul J. Cullen, Anuj Kumar Pseudohyphal growth is a nutrient-regulated program in which budding yeast form multicellular filaments of elongated and connected cells. Filamentous growth is required ...

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Non-linear hierarchy of the quorum sensing signalling pathway in bloodstream form African trypanosomes

25-Jun-2018 | Lindsay McDonald; Mathieu Cayla; Alasdair Ivens; Binny Mony; Paula MacGregor; Eleanor Silvester; Kirsty McWilliam; K ..., PLoS Pathogens, 2018

by Lindsay McDonald, Mathieu Cayla, Alasdair Ivens, Binny Mony, Paula MacGregor, Eleanor Silvester, Kirsty McWilliam, Keith R. Matthews Trypanosoma brucei, the agents of African trypanosomiasis, undergo density-dependent differentiation in the mammalian bloodstream to prepare for transmission ...

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OFF-responses of interneurons optimize avoidance behaviors depending on stimulus strength via electrical synapses

25-Jun-2018 | Sayaka Hori; Shigekazu Oda; Yuji Suehiro; Yuichi Iino; Shohei Mitani, PLoS Genetics, 2018

by Sayaka Hori, Shigekazu Oda, Yuji Suehiro, Yuichi Iino, Shohei Mitani Optimization of the types and timing of avoidance behaviors depending on the intensity of a noxious stimulus is essential for survival; however, processing in the central nervous system and its developmental basis are ...

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B cell clonal lineage alterations upon recombinant HIV-1 envelope immunization of rhesus macaques

22-Jun-2018 | Christina Yacoob; Miles Darnell Lange; Kristen Cohen; Kanan Lathia; Junli Feng; Jolene Glenn; Sara Carbonetti; Brian ..., PLoS Pathogens, 2018

by Christina Yacoob, Miles Darnell Lange, Kristen Cohen, Kanan Lathia, Junli Feng, Jolene Glenn, Sara Carbonetti, Brian Oliver, Vladimir Vigdorovich, David Noah Sather, Leonidas Stamatatos Broadly neutralizing HIV-1 antibodies (bNAbs) isolated from infected subjects display protective potential ...

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Pharmaceuticals, Vol. 11, Pages 61: Proximal Pathway Enrichment Analysis for Targeting Comorbid Diseases via Network Endopharmacology

22-Jun-2018 | Aguirre-Plans, Joaquim ; Piñero, Janet ; Menche, Jörg ; Sanz, Ferran ; Furlong, Laura I.; Schmidt, Harald H. H. W. ..., Pharmaceuticals, 2018

Pharmaceuticals, Vol. 11, Pages 61: Proximal Pathway Enrichment Analysis for Targeting Comorbid Diseases via Network Endopharmacology Pharmaceuticals doi: 10.3390/ph11030061 Authors: Joaquim Aguirre-Plans Janet Piñero Jörg Menche Ferran Sanz Laura I. Furlong Harald H. H. W. ...

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