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32,922 Newest Publications about the topic genes


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Investigation of a common gene expression signature in gastrointestinal cancers using systems biology approaches

13-Sep-2017 | Kaveh Baghaei; Nazanin Hosseinkhan; Hamid Asadzadeh Aghdaei; M. R. Zali, Molecular BioSystems, 2017

According to GLOBOCAN 2012, the incidence and the mortality rate of colorectal, stomach and liver cancers are the highest among the total gastrointestinal (GI) cancers. Here we aimed to find the common genes and pathways that are simultaneously deregulated in these three malignancies using ...


Viruses, Vol. 9, Pages 252: Analysis of Class I Major Histocompatibility Complex Gene Transcription in Human Tumors Caused by Human Papillomavirus Infection

10-Sep-2017 | Gameiro, Steven F.; Zhang, Ali ; Ghasemi, Farhad ; Barrett, John W.; Nichols, Anthony C.; Mymryk, Joe S., Viruses, 2017

Viruses, Vol. 9, Pages 252: Analysis of Class I Major Histocompatibility Complex Gene Transcription in Human Tumors Caused by Human Papillomavirus Infection Viruses doi: 10.3390/v9090252 Authors: Steven Gameiro Ali Zhang Farhad Ghasemi John Barrett Anthony Nichols Joe ...


Mutations in KARS cause early‐onset hearing loss and leukoencepha lopathy: Potential pathogenic mechanism

09-Sep-2017 | Xiao‐Long Zhou, Long‐Xia He, Li‐Jia Yu, Yong Wang, Xi‐Jin Wang, En‐Duo Wang, Tao Yang, Human Mutation, 2017

Abstract Leukoencephalopathies are a broad class of common neurologic deterioration for which the etiology remain unsolved in many cases. In a Chinese Han family segregated with sensorineural hearing loss and leukoencephalopathy, candidate pathogenic variants were identified by targeted ...


Wide‐spread Transcriptional Alternations in Oligodendrocytes in the Adult Mouse Brain following Chronic Stress

08-Sep-2017 | Jia Liu, Karen Dietz, Georgia E. Hodes, Scott J. Russo, Patrizia Casaccia, Developmental Neurobiology, 2017

Abstract Emerging evidence shows that oligodendrogenesis and myelination are highly responsive to behavioral experience, including physical activity and social experience. This form of myelin plasticity is being increasingly appreciated and examined in the prefrontal cortex (PFC), a critical ...


Peeling skin syndrome associated with novel variant in FLG2 gene

08-Sep-2017 | Ahmed Alfares, Sultan Al‐Khenaizan, Fuad Al Mutairi, American Journal of Medical Genetics Part A, 2017

Peeling skin syndrome is a rare genodermatosis characterized by variably pruritic superficial generalized peeling of the skin with several genes involved until now little is known about the association between FLG2 and peeling skin syndrome. We describe multiple family members from a ...


Chimerism for 20q11.2 microdeletion of GDF5 explains discordant phenotypes in monochorionic‐diamniotic twins

08-Sep-2017 | Matthew M. Meredith, Beau Crabb, Marcelo Vargas, Betsy A. Hirsch, American Journal of Medical Genetics Part A, 2017

Microdeletions of 20q11.2 are rare but have been associated with characteristic clinical findings. A 1.6 Mb minimal critical region has been identified that includes three OMIM genes: GDF5, EPB41L1, and SAMHD. Here we describe a male monozygotic, monochorionic‐diamniotic twin pair with ...


LncRNA‐ATB: An indispensable cancer‐related long noncoding RNA

08-Sep-2017 | Jinglin Li, Zhenglong Li, Wangyang Zheng, Xinheng Li, Zhidong Wang, Yunfu Cui, Xingming Jiang, Cell Proliferation, 2017

Abstract Objectives Long non‐coding RNAs (lncRNAs) are a group of non‐protein‐coding RNAs that are greater than 200 nucleotides in length. Increasing evidence indicates that lncRNAs, which may serve as either oncogenes or tumour suppressor genes, play a vital role in the pathophysiology of ...


Aldo‐keto reductase and alcohol dehydrogenase contribute to benznidazole natural resistance in Trypanosoma cruzi

08-Sep-2017 | Laura González, Paola García‐Huertas, Omar Triana‐Chávez, Gabriela Andrea García, Silvane Maria Fonseca Murta, Ana M ..., Molecular Microbiology, 2017

Summary The improvement of Chagas disease treatment is focused not only on the development of new drugs but also in understanding mechanisms of action and resistance to drugs conventionally used. Thus, some strategies aim to detect specific changes in proteins between sensitive and resistant ...


Efficient Secretion of Three Fungal Laccases from Saccharomyces cerevisiae and Their Potential for Decolorization of Textile Industry Effluent – a Comparative Study

08-Sep-2017 | Zuzana Antošová, Klára Herkommerová, Iva Pichová, Hana Sychrová, Biotechnology Progress, 2017

Abstract Laccases are enzymes with a broad range of biotechnological applications and have, for example, the ability to oxidize many xenobiotics including synthetic dyes. In order to obtain an efficient laccase for the decolorization of dyes which spoil wastewater from the textile industry, ...


Microbial Expansins

08-Sep-2017 | Daniel J. Cosgrove, Annual Review of Microbiology, 2017

Expansins are small proteins that loosen plant cell walls and cellulosic materials without lytic activity. First discovered in plants, expansin genes are found in the genomes of numerous bacteria and fungi that interact with plants in pathogenic and mutualistic patterns, as well as in microbes ...


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