01-06-2013 | Yann Lesecque; Dominique Mouchiroud; Laurent Duret, Molecular Biology and Evolution, 2013

GC-biased gene conversion (gBGC) is a process associated with recombination that favors the transmission of GC alleles over AT alleles during meiosis. gBGC plays a major role in genome evolution in many eukaryotes. However, the molecular mechanisms of gBGC are still unknown. Different steps ...

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01-06-2013 | Alison C MacKinnon; Xiaojun Liu; Patrick WF Hadoke; Mark R Miller; David E Newby; Tariq Sethi, Glycobiology , 2013

Atherosclerosis is a major risk factor for cardiovascular disease (CVD) and stroke. Galectin-3 is a carbohydrate-binding lectin implicated in the pathophysiology of CVD and is highly expressed within atherosclerotic lesions in mice and humans. The object of this present study was to use ...

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15-05-2013 | Haiyang Wang; Yue Zheng; Genlin Wang; Huixia Li, Molecular BioSystems, 2013

microRNA (miRNA) are endogenous non-coding RNA that has been proposed play important roles in the formation of body fat. However, the differential expression of miRNA and the role of these miRNA in bovine intramuscular and subcutaneous fat tissue are still unknown. In this study, profile of ...

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15-05-2013 | Michael Bressan, Gary Liu, Takashi Mikawa, Science , 2013

A region of the lateral plate mesoderm gives rise to the cardiac pacemaker cell lineage prior to the onset of heart formation.

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15-05-2013 | Ricardo Rodríguez-Calvo; Anna Guadall; Olivier Calvayrac; María A. Navarro; Judith Alonso; Beatriz Ferrán; Alicia de ..., Human Molecular Genetics, 2013

We have previously shown that NOR-1 (NR4A3) modulates the proliferation and survival of vascular cells in culture. However, in genetically modified animal models, somewhat conflicting results have been reported concerning the involvement of NOR-1 in neointimal formation after vascular ...

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15-05-2013 | Rachel J. Watkins; Rajashree Patil; Benjamin T. Goult; Mervyn G. Thomas; Irene Gottlob; Sue Shackleton, Human Molecular Genetics, 2013

Idiopathic infantile nystagmus (IIN) is a genetically heterogeneous disorder of eye movement that can be caused by mutations in the FRMD7 gene that encodes a FERM domain protein. FRMD7 is expressed in the brain and knock-down studies suggest it plays a role in neurite extension through ...

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15-05-2013 | David R. Crosslin; Andrew McDavid; Noah Weston; Xiuwen Zheng; Eugene Hart; Mariza de Andrade; Iftikhar J. Kullo; Cat ..., Human Molecular Genetics, 2013

With white blood cell count emerging as an important risk factor for chronic inflammatory diseases, genetic associations of differential leukocyte types, specifically monocyte count, are providing novel candidate genes and pathways to further investigate. Circulating monocytes play a ...

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15-05-2013 | Science , 2013

Simulating Foam Formation | Defense and Counter-Defense | Building Better Vaccines | A Phase for Fano | Making Metamaterials | Dust in the Clouds | Setting the Pace | Identical and Still Different | Infections Against Infection | Of Mice and Markets | Creating Unstable Atomic Orbitals | ...

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12-05-2013 | Author(s): Tsung-Wei Huang , Yen-Hui Chan , Huang-Wei Su , Ya-Shuan Chou , Tai-Horng Young, Acta Biomaterialia, 2013

Publication date: June 2013 Source:Acta Biomaterialia, Volume 9, Issue 6 Author(s): Tsung-Wei Huang , Yen-Hui Chan , Huang-Wei Su , Ya-Shuan Chou , Tai-Horng Young While playing a major role in maintaining the mucociliary phenotype of respiratory epithelial cells (RECs), retinoids ...

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12-05-2013 | Author(s): Xi Liu , Xiumei Wang , Xiujuan Wang , Hui Ren , Jin He , Lin Qiao , Fu-Zhai Cui, Acta Biomaterialia, 2013

Publication date: June 2013 Source:Acta Biomaterialia, Volume 9, Issue 6 Author(s): Xi Liu , Xiumei Wang , Xiujuan Wang , Hui Ren , Jin He , Lin Qiao , Fu-Zhai Cui A class of designer functionalized self-assembling peptide nanofiber scaffolds developed from self-assembling ...

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