To use all functions of this page, please activate cookies in your browser.
My watch list
my.bionity.com
my.bionity.com
With an accout for my.bionity.com you can always see everything at a glance – and you can configure your own website and individual newsletter.
- My watch list
- My saved searches
- My saved topics
- My newsletter
568 Newest Publications about the topic birth defects
rss
Sirenomelia after phenobarbital and carbamazepine therapy in pregnancy
15-06-2013 | Oana Sorina Tica, Andrei Adrian Tica, Cristina Gabriela Brailoiu, Nicolae Cernea, Vlad Iustin Tica, Birth Defects Research Part A: Clinical and Molecular Teratology, 2013
BACKGROUND Epilepsy still remains a serious challenge for any obstetrician due to the potential teratogenicity of all antiepileptics. However, without appropriate therapy the seizures can reappear, with direct negative impact on fetus. Currently, sirenomelia is the most severe caudal pole ...
Association between PTCH1 polymorphisms and risk of neural tube defects in a Chinese population
13-06-2013 | Zhen Wang, Li Wang, Shaofang Shangguan, Xiaolin Lu, Shaoyan Chang, Jianhua Wang, Jizhen Zou, Lihua Wu, Ting Zhang, Y ..., Birth Defects Research Part A: Clinical and Molecular Teratology, 2013
BACKGROUND SHH signaling pathway plays an important role in the formation of the neural plate and is involved in the regulation of the dorsoventral (DV) axis of the neural tube. Some neural tube defects (NTDs) may be caused through overactivation of the SHH signaling pathway. The PTCH1 ...
Case of cephalothoracopagus conjoined twinning in an embryonic mouse
13-06-2013 | Thomas E. Hynd, Cadie L. Buckley, Scott Lozanoff, Birth Defects Research Part A: Clinical and Molecular Teratology, 2013
BACKGROUND Cephalothoracopagus twinning is extremely rare, and it is characterized by fusion of the head and thorax, two separate spines, pelves, and fore‐ and hindlimbs. CASE: In this case study, we describe cephalothoracopagus twinning in an embryonic mouse displaying a large but ...
Red blood cell folate levels in pregnant women with a history of mood disorders: A case series
13-06-2013 | Elyse Yaremco, Angela Inglis, Sheila M. Innis, Catriona Hippman, Prescilla Carrion, Yvonne Lamers, William G. Honer, ..., Birth Defects Research Part A: Clinical and Molecular Teratology, 2013
BACKGROUND Maternal folate supplementation reduces offspring risk for neural tube defects (NTDs) and other congenital abnormalities. Maternal red blood cell (RBC) folate concentrations of >906 nmol/L have been associated with the lowest risk of having an neural tube defect affected ...
Hispanic ethnicity and acculturation, maternal age and the risk of gastroschisis in the national birth defects prevention study
03-06-2013 | Zeina G. Khodr, Philip J. Lupo, Mark A. Canfield, Wenyaw Chan, Yi Cai, Laura E. Mitchell, Birth Defects Research Part A: Clinical and Molecular Teratology, 2013
Introduction Studies indicate that gastroschisis is associated with maternal age, ethnicity, and acculturation. This analysis was conducted to further define the associations between gastroschisis and parental Hispanic ethnicity and acculturation, and to determine whether such ...
Is LMNB1 a susceptibility gene for neural tube defects in humans?
03-06-2013 | Alexis Robinson, Darren Partridge, Ashraf Malhas, Sandra C.P. Castro, Peter Gustavsson, Dominic N. Thompson, David J ..., Birth Defects Research Part A: Clinical and Molecular Teratology, 2013
BACKGROUND Lamins are intermediate filament proteins that form a major component of the nuclear lamina, a protein complex at the surface of the inner nuclear membrane. Numerous clinically diverse conditions, termed laminopathies, have been found to result from mutation of LMNA. In ...
Valproate prescriptions for nonepilepsy disorders in reproductive‐age women
03-06-2013 | Demilade A. Adedinsewo, David J. Thurman, Yao‐Hua Luo, Rebecca S. Williamson, Oluwaseun A. Odewole, Godfrey P. Oakley, Birth Defects Research Part A: Clinical and Molecular Teratology, 2013
BACKGROUND Scientific evidence has consistently shown taking valproate during pregnancy increases risks of congenital malformations and cognitive impairment. As such, elimination of its use would be an important step in birth defects prevention. There are guidelines discouraging its use ...
Arrhenius thermodynamics and birth defects: Chemical teratogen synergy. Untested, testable, and projected relevance
31-05-2013 | Morton W. Miller, Charles C. Church, Birth Defects Research Part C: Embryo Today: Reviews, 2013
This article addresses the issue of hyperthermia‐induced birth defects with an accompanying additional teratogen, be it a chemical or a physical agent (i.e., a simultaneous “combinational” exposure to two teratogens, one of which is hyperthermia). Hyperthermia per se is a recognized human ...
Zebrafish model systems for developmental neurobehavioral toxicology
31-05-2013 | Jordan Bailey, Anthony Oliveri, Edward D. Levin, Birth Defects Research Part C: Embryo Today: Reviews, 2013
Zebrafish offer many advantages that complement classic mammalian models for the study of normal development as well as for the teratogenic effects of exposure to hazardous compounds. The clear chorion and embryo of the zebrafish allow for continuous visualization of the anatomical changes ...
Follistatin‐like 1 in vertebrate development
31-05-2013 | M. Sylva, A.F.M. Moorman, M.J.B. Hoff, Birth Defects Research Part C: Embryo Today: Reviews, 2013
Follistatin‐like 1 (Fstl1) is a member of the secreted protein acidic rich in cysteins (SPARC) family and has been implicated in many different signaling pathways, including bone morphogenetic protein (BMP) signaling. In many different developmental processes like, dorso‐ventral axis ...
Netmeeting
