My watch list  

1,751 Newest Publications about the topic biochemistry


Quality Control Test for Sequence-Phenotype Assignments

20-Feb-2015 | Maria Teresa Lara Ortiz et al., PLoS ONE, 2015

by Maria Teresa Lara Ortiz, Pablo Benjamín Leon Rosario, Pablo Luna-Nevarez, Alba Savin Gamez, Ana Martínez-del Campo, Gabriel Del Rio Relating a gene mutation to a phenotype is a common task in different disciplines such as protein biochemistry. In this endeavour, it is common to find false ...


An alternative laboratory designed to address ethical concerns associated with traditional TAS2R38 student genotyping

20-Feb-2015 | Michelle L. LaBonte, Melissa A. Beers, Biochemistry and Molecular Biology Education, 2015

Abstract The TAS2R38 alleles that code for the PAV/AVI T2R38 proteins have long been viewed as benign taste receptor variants. However, recent studies have demonstrated an expanding and medically relevant role for TAS2R38. The AVI variant of T2R38 is associated with an increased risk of both ...


Leading the way: Changing the focus from teaching to learning in large subjects with limited budgets

20-Feb-2015 | Karen Fildes, Tracey Kuit, Glennys O'Brien, Lynne Keevers, Simon Bedford, Biochemistry and Molecular Biology Education, 2015

Abstract To lead positive change in the teaching practice of teams that service large numbers of diverse students from multiple degree programs provides many challenges. The primary aim of this study was to provide a clear framework on which to plan the process of change that can be utilized ...


Proteopedia: Rossmann fold: A beta‐alpha‐beta fold at dinucleotide binding sites

20-Feb-2015 | Israel Hanukoglu, Biochemistry and Molecular Biology Education, 2015

Abstract The Rossmann fold is one of the most common and widely distributed super‐secondary structures. It is composed of a series of alternating beta strand (β) and alpha helical (α) segments wherein the β‐strands are hydrogen bonded forming a β‐sheet. The initial beta‐alpha‐beta (βαβ) fold ...


What is the true nitrogenase reaction? A guided approach

20-Feb-2015 | Piero L. Ipata, Rossana Pesi, Biochemistry and Molecular Biology Education, 2015

Abstract Only diazotrophic bacteria, called Rizhobia, living as symbionts in the root nodules of leguminous plants and certain free‐living prokaryotic cells can fix atmospheric N2. In these microorganisms, nitrogen fixation is carried out by the nitrogenase protein complex. However, the ...


Characterization of the Mycobacterial Acyl-CoA Carboxylase Holo Complexes Reveals Their Functional Expansion into Amino Acid Catabolism

19-Feb-2015 | Matthias T. Ehebauer et al., PLoS Pathogens, 2015

by Matthias T. Ehebauer, Michael Zimmermann, Arjen J. Jakobi, Elke E. Noens, Daniel Laubitz, Bogdan Cichocki, Hedia Marrakchi, Marie-Antoinette Lanéelle, Mamadou Daffé, Carsten Sachse, Andrzej Dziembowski, Uwe Sauer, Matthias Wilmanns Biotin-mediated carboxylation of short-chain fatty acid ...


Mitochondrial peroxiredoxin functions as crucial chaperone reservoir in Leishmania infantum [Biochemistry]

17-Feb-2015 | Filipa Teixeira; Helena Castro; Tânia Cruz; Eric Tse; Philipp Koldewey; Daniel R. Southworth; Ana M. Tomás; Ursula Jakob, Proceedings of the National Academy of Sciences current issue, 2015

Cytosolic eukaryotic 2-Cys-peroxiredoxins have been widely reported to act as dual-function proteins, either detoxifying reactive oxygen species or acting as chaperones to prevent protein aggregation. Several stimuli, including peroxide-mediated sulfinic acid formation at the active site ...


Structural basis for transcription reactivation by RapA [Biochemistry]

17-Feb-2015 | Bin Liu; Yuhong Zuo; Thomas A. Steitz, Proceedings of the National Academy of Sciences current issue, 2015

RNA polymerase (RNAP) loses activity during transcription as it stalls at various inactive states due to erratic translocation. Reactivation of these stalled RNAPs is essential for efficient RNA synthesis. Here we report a 4.7-Å resolution crystal structure of the Escherichia coli RNAP core ...


Distinct activation of an E2 ubiquitin-conjugating enzyme by its cognate E3 ligases [Biochemistry]

17-Feb-2015 | Itamar Cohen; Reuven Wiener; Yuval Reiss; Tommer Ravid, Proceedings of the National Academy of Sciences current issue, 2015

A significant portion of ubiquitin (Ub)-dependent cellular protein quality control takes place at the endoplasmic reticulum (ER) in a process termed “ER-associated degradation” (ERAD). Yeast ERAD employs two integral ER membrane E3 Ub ligases: Hrd1 (also termed “Der3”) and Doa10, which recognize ...


A conserved amphipathic helix is required for membrane tubule formation by Yop1p [Biochemistry]

17-Feb-2015 | Jacob P. Brady; Jolyon K. Claridge; Peter G. Smith; Jason R. Schnell, Proceedings of the National Academy of Sciences current issue, 2015

The integral membrane proteins of the DP1 (deleted in polyposis) and reticulon families are responsible for maintaining the high membrane curvature required for both smooth endoplasmic reticulum (ER) tubules and the edges of ER sheets, and mutations in these proteins lead to motor neuron ...


Page 1 From 176
Subscribe to e-mail updates relating to your search

You will receive via e-mail the latest search results matching your search criteria. This service is free of charge and can be cancelled at any time.

Your browser is not current. Microsoft Internet Explorer 6.0 does not support some functions on Chemie.DE