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1,660 Newest Publications about the topic biochemistry

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Ultraviolet Index and Location are Important Determinants of Vitamin D Status in People with Human Immunodeficiency Virus (HIV)

14-11-2014 | Karen M Klassen, Christopher K Fairley, Michael G Kimlin, Mark Kelly, Tim RH Read, Jennifer Broom, Darren B Russell, ..., Photochemistry and Photobiology, 2014

Abstract This study aimed to document the vitamin D status of HIV‐infected individuals across a wide latitude range in one country and to examine associated risk factors for low vitamin D. Using data from patients attending four HIV specialist clinics across a wide latitude range in Australia, ...

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Simulating an investigative study of clinical cancer samples: Use of tissue slides and PCR‐based promoter‐hypermethylation analysis

14-11-2014 | Yuan Yuan Chew, Cheen Fei Chin, Foong May Yeong, Biochemistry and Molecular Biology Education, 2014

Abstract Topics on the molecular basis underlying cancer are quite popular among students. Also, excellent textbooks abound that provide interesting materials for discussion during lectures and tutorials about major events leading to cancer formation and progression. However, much less is ...

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Dr. Earl N. Meyer, in the lab, with a scalpel: A murder mystery as a biochemistry recruitment tool

14-11-2014 | Felicia Vulcu, Meagan Heirwegh, Biochemistry and Molecular Biology Education, 2014

Abstract Increasing student participation in science is an ongoing challenge for many universities. In this active learning workshop, centered on inquiry and teamwork, we introduce high‐school students to biochemistry and molecular biology techniques using a murder mystery activity. During ...

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Using an international p53 mutation database as a foundation for an online laboratory in an upper level undergraduate biology class

14-11-2014 | Patricia G. Melloy, Biochemistry and Molecular Biology Education, 2014

Abstract A two‐part laboratory exercise was developed to enhance classroom instruction on the significance of p53 mutations in cancer development. Students were asked to mine key information from an international database of p53 genetic changes related to cancer, the IARC TP53 database. Using ...

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Fluorescence quantum yield measurements of fluorescent proteins: A laboratory experiment for a biochemistry or molecular biophysics laboratory course

14-11-2014 | Kathryn P. Wall, Rebecca Dillon, Michelle K. Knowles, Biochemistry and Molecular Biology Education, 2014

Abstract Fluorescent proteins are commonly used in cell biology to assess where proteins are within a cell as a function of time and provide insight into intracellular protein function. However, the usefulness of a fluorescent protein depends directly on the quantum yield. The quantum yield ...

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Assessing the engagement, learning, and overall experience of students operating an atomic absorption spectrophotometer with remote access technology

14-11-2014 | Daniel J. Erasmus, Sharon E. Brewer, Bruno Cinel, Biochemistry and Molecular Biology Education, 2014

Abstract The use of internet‐based technologies in the teaching of laboratories has emerged as a promising education tool. This study evaluated the effectiveness of using remote access technology to operate an atomic absorption spectrophotometer in analyzing the iron content in a crude ...

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Learning about solubility

14-11-2014 | Dino G. Salinas, Juan G. Reyes, Biochemistry and Molecular Biology Education, 2014

Abstract Qualitative questions are proposed to assess the understanding of solubility and some of its applications. To improve those results, a simple quantitative problem on the precipitation of proteins is proposed. © 2014 by The International Union of Biochemistry and Molecular Biology, ...

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A simple theoretical model goes a long way in explaining complex behavior in protein folding [Biophysics and Computational Biology]

11-11-2014 | Victor Muñoz, Proceedings of the National Academy of Sciences current issue, 2014

Understanding how natural proteins fold spontaneously onto their specific, biologically functional 3D structures is both a fascinating fundamental problem in modern biochemistry and a necessary step toward developing technologies for protein engineering and designing protein-based nanodevices. ...

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The mechanism of Torsin ATPase activation [Biochemistry]

11-11-2014 | Rebecca S. H. Brown; Chenguang Zhao; Anna R. Chase; Jimin Wang; Christian Schlieker, Proceedings of the National Academy of Sciences current issue, 2014

Torsins are membrane-associated ATPases whose activity is dependent on two activating cofactors, lamina-associated polypeptide 1 (LAP1) and luminal domain-like LAP1 (LULL1). The mechanism by which these cofactors regulate Torsin activity has so far remained elusive. In this study, we identify a ...

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Selective allosteric coupling in core chemotaxis signaling complexes [Biochemistry]

11-11-2014 | Mingshan Li; Gerald L. Hazelbauer, Proceedings of the National Academy of Sciences current issue, 2014

Bacterial chemotaxis is mediated by signaling complexes that sense chemical gradients and direct bacteria to favorable environments by controlling a histidine kinase as a function of chemoreceptor ligand occupancy. Core signaling complexes contain two trimers of transmembrane chemoreceptor ...

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