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1,634 Newest Publications about the topic biochemistry

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Interactive Hangman teaches amino acid structures and abbreviations

25-10-2014 | Britney O. Pennington, Duane Sears, Dennis O. Clegg, Biochemistry and Molecular Biology Education, 2014

Abstract We developed an interactive exercise to teach students how to draw the structures of the 20 standard amino acids and to identify the one‐letter abbreviations by modifying the familiar game of “Hangman.” Amino acid structures were used to represent single letters throughout the game. ...

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Biochemical analysis of ascites fluid as an aid to etiological diagnosis: a series of 100 cases of non‐immune fetal ascites

25-10-2014 | Sophie Dreux, Laurent J. Salomon, Jonathan Rosenblatt, Romain Favre, Véronique Houfflin‐Debarge, Bernard Broussin, F ..., Prenatal Diagnosis, 2014

ABSTRACT Objective To analyze the contribution of biochemistry and cytology of fetal ascites fluid to the etiological diagnosis of ascites after ultrasonographic scan, maternal blood sampling and fetal karyotyping. Method Retrospective study of 100 consecutive cases of non‐immune ...

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A guide to using case‐based learning in biochemistry education

23-10-2014 | Verena Kulak, Genevieve Newton, Biochemistry and Molecular Biology Education, 2014

Abstract Studies indicate that the majority of students in undergraduate biochemistry take a surface approach to learning, associated with rote memorization of material, rather than a deep approach, which implies higher cognitive processing. This behavior relates to poorer outcomes, including ...

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Diverse assessment and active student engagement sustain deep learning: A comparative study of outcomes in two parallel introductory biochemistry courses

23-10-2014 | Samantha J. Bevan, Cecilia W. L. Chan, Julian A. Tanner, Biochemistry and Molecular Biology Education, 2014

Abstract Although there is increasing evidence for a relationship between courses that emphasize student engagement and achievement of student deep learning, there is a paucity of quantitative comparative studies in a biochemistry and molecular biology context. Here, we present a pedagogical ...

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An adaptable investigative graduate laboratory course for teaching protein purification

21-10-2014 | Christopher W. Carroll, Lani C. Keller, Biochemistry and Molecular Biology Education, 2014

Abstract This adaptable graduate laboratory course on protein purification offers students the opportunity to explore a wide range of techniques while allowing the instructor the freedom to incorporate their own personal research interests. The course design involves two sequential ...

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Isolation and genetic analysis of an environmental bacteriophage: A 10‐session laboratory series in molecular virology

21-10-2014 | Ryan P. Williamson, Brent T. Barker, Hamidou Drammeh, Jefferson Scott, Joseph Lin, Biochemistry and Molecular Biology Education, 2014

Abstract Bacterial viruses, otherwise known as bacteriophage (or phage), are some of the most abundant viruses found in the environment. They can be easily isolated from water or soil and are ideal for use in laboratory classrooms due to their ease of culture and inherent safety. Here, we ...

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PhD trainees should be empowered to leverage dueling priorities

21-10-2014 | Viviane Callier, Nathan L. Vanderford, Biochemistry and Molecular Biology Education, 2014

Abstract For young scientists, awareness of how academic institutions function is key for making the most of their trainee years. © 2014 by The International Union of Biochemistry and Molecular Biology, 2014.

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Label-free electrochemical detection of human methyltransferase from tumors [Biochemistry]

21-10-2014 | Ariel L. Furst; Natalie B. Muren; Michael G. Hill; Jacqueline K. Barton, Proceedings of the National Academy of Sciences current issue, 2014

The role of abnormal DNA methyltransferase activity in the development and progression of cancer is an essential and rapidly growing area of research, both for improved diagnosis and treatment. However, current technologies for the assessment of methyltransferase activity, particularly from crude ...

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The signaling phospholipid PIP3 creates a new interaction surface on the nuclear receptor SF-1 [Biochemistry]

21-10-2014 | Raymond D. Blind; Elena P. Sablin; Kristopher M. Kuchenbecker; Hsiu-Ju Chiu; Ashley M. Deacon; Debanu Das; Robert J. ..., Proceedings of the National Academy of Sciences current issue, 2014

The signaling phosphatidylinositol lipids PI(4,5)P2 (PIP2) and PI(3,4,5)P3 (PIP3) bind nuclear receptor 5A family (NR5As), but their regulatory mechanisms remain unknown. Here, the crystal structures of human NR5A1 (steroidogenic factor-1, SF-1) ligand binding domain (LBD) bound to PIP2 and PIP3 ...

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Activation of the pseudokinase MLKL unleashes the four-helix bundle domain to induce membrane localization and necroptotic cell death [Biochemistry]

21-10-2014 | Joanne M. Hildebrand; Maria C. Tanzer; Isabelle S. Lucet; Samuel N. Young; Sukhdeep K. Spall; Pooja Sharma; Catia Pi ..., Proceedings of the National Academy of Sciences current issue, 2014

Necroptosis is considered to be complementary to the classical caspase-dependent programmed cell death pathway, apoptosis. The pseudokinase Mixed Lineage Kinase Domain-Like (MLKL) is an essential effector protein in the necroptotic cell death pathway downstream of the protein kinase Receptor ...

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