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347 Newest Publications about the topic bacterial infection
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CD3−NK1.1+ cells aid in the early induction of a Th1 response to an attaching and effacing enteric pathogen
14-06-2013 | Sarah A. Reid‐Yu, Cherrie‐Lee N. Small, Brian K. Coombes, European Journal of Immunology, 2013
Extracellular attaching and effacing (A/E) pathogens including pathogenic E. coli colonize the host gut causing diarrhea and inflammation. Although much is known regarding the pathogenesis of A/E bacteria, there remains an incomplete understanding of host immune responses to these microbes. ...
[Report] Role of Tissue Protection in Lethal Respiratory Viral-Bacterial Coinfection
12-06-2013 | Amanda M. Jamieson, Lesley Pasman, Shuang Yu, Pia Gamradt, Robert J. Homer, Thomas Decker, Ruslan Medzhitov, Science , 2013
Reduced immune tolerance, rather than resistance, increases the susceptibility of mice to a secondary bacterial infection.
Shigella IpaH0722 E3 Ubiquitin Ligase Effector Targets TRAF2 to Inhibit PKC–NF-κB Activity in Invaded Epithelial Cells
06-06-2013 | Hiroshi Ashida et al., PLoS Pathogens, 2013
by Hiroshi Ashida, Hiroyasu Nakano, Chihiro Sasakawa NF-κB plays a central role in modulating innate immune responses to bacterial infections. Therefore, many bacterial pathogens deploy multiple mechanisms to counteract NF-κB activation. The invasion of and subsequent replication of ...
Sputum Inflammatory Cell-Based Classification of Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease
31-05-2013 | Peng Gao et al., PLoS ONE, 2013
by Peng Gao, Jie Zhang, Xiaoyan He, Yuqiu Hao, Ke Wang, Peter G. Gibson Background Patients with chronic obstructive pulmonary disease (COPD) commonly suffer from acute exacerbations (AECOPD) and display varying disease severity. However, there is no available biomarker for the ...
Phage cocktails and the future of phage therapy
23-05-2013 | Benjamin K Chan; Stephen T Abedon; Catherine Loc-Carrillo, Future Microbiology, 2013
Viruses of bacteria, known as bacteriophages or phages, were discovered nearly 100 years ago. Their potential as antibacterial agents was appreciated almost immediately, with the first ‘phage therapy’ trials predating Fleming’s discovery of penicillin by approximately a decade. In this ...
Application of quantitative proteomic analysis using tandem mass tags for discovery and identification of novel biomarkers in periodontal disease
21-05-2013 | Sachio Tsuchida, Mamoru Satoh, Yusuke Kawashima, Kazuyuki Sogawa, Sayaka Kado, Setsu Sawai, Motoi Nishimura, Mayumi ..., PROTEOMICS, 2013
Periodontal disease is a bacterial infection that destroys the gingiva and surrounding tissues of the oral cavity. Gingival crevicular fluid (GCF) is extracted from the gingival sulcus and pocket. Analysis of biochemical markers in GCF, which predict the progression of periodontal disease, ...
Characterization of a virulent bacteriophage LK1 specific for Citrobacter freundii isolated from sewage water
20-05-2013 | Waqas Nasir Chaudhry, Irshad Ul Haq, Saadia Andleeb, Ishtiaq Qadri, Journal of Basic Microbiology, 2013
Abstract Citrobacter freundii is a worldwide emerging nosocomial pathogen with escalating incidence of multidrug resistance. Citrobacter freundii exists in natural environment, especially in health care settings and is difficult to eradicate. Phage therapy is considered as an alternative ...
NOD2-mediated Suppression of CD55 on Neutrophils Enhances C5a Generation During Polymicrobial Sepsis
09-05-2013 | Sae Jin Oh et al., PLoS Pathogens, 2013
by Sae Jin Oh, Ji Hyung Kim, Doo Hyun Chung Nucleotide-binding oligomerization domain (NOD) 2 is a cytosolic protein that plays a defensive role in bacterial infection by sensing peptidoglycans. C5a, which has harmful effects in sepsis, interacts with innate proteins. However, whether NOD2 ...
[Report] Heterogeneous Differentiation Patterns of Individual CD8+ T Cells
08-05-2013 | Carmen Gerlach, Jan C. Rohr, Leïla Perié, Nienke van Rooij, Jeroen W. J. van Heijst, Arno Velds, Jos Urbanus, Shali ..., Science , 2013
The single-cell dynamics as cytotoxic T cells respond to a bacterial infection are analyzed in mice.
[Report] Disparate Individual Fates Compose Robust CD8+ T Cell Immunity
08-05-2013 | Veit R. Buchholz, Michael Flossdorf, Inge Hensel, Lorenz Kretschmer, Bianca Weissbrich, Patricia Gräf, Admar Versch ..., Science , 2013
The single-cell dynamics as cytotoxic T cells respond to a bacterial infection are analyzed in mice.
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