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885 Newest Publications about the topic anxiety

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Deletion of the miR-379/miR-410 gene cluster at the imprinted Dlk1-Dio3 locus enhances anxiety-related behaviour

15-Feb-2016 | Virginie Marty; Stéphane Labialle; Marie-Line Bortolin-Cavaillé; Gabriela Ferreira De Medeiros; Marie-Pierre Moisan; ..., Human Molecular Genetics, 2016

The brain-specific miR-379/miR-410 gene cluster at the imprinted Dlk1-Dio3 domain is implicated in several aspects of brain development and function, particularly in fine-tuning the dendritic outgrowth and spine remodelling of hippocampal neurons. Whether it might influence behaviour and ...

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Treatment of anxiety and depression: Medicinal plants in retrospect

06-Feb-2016 | James Oluwagbamigbe Fajemiroye, Dayane Moreira da Silva, Danillo Ramos Oliveira, Elson Alves Costa, Fundamental & Clinical Pharmacology, 2016

Abstract Anxiety and depression are complex heterogeneous psychiatric disorders and leading causes of disability worldwide. This review summarizes reports on the fundamentals, prevalence, diagnosis, neurobiology, advancement in treatment of these disease and preclinical assessment of ...

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Possible Involvement of Nitric Oxide Modulatory Mechanisms in the Neuroprotective Effect of Centella asiatica Against Sleep Deprivation Induced Anxiety Like Behaviour, Oxidative Damage and Neuroinflammation

05-Feb-2016 | Priyanka Chanana, Anil Kumar, Phytotherapy Research, 2016

Sleep deprivation (SD) is an experience of inadequate or poor quality of sleep that may produce significant alterations in multiple neural systems. Centella asiatica (CA) is a psychoactive medicinal herb with immense therapeutic potential. The present study was designed to explore the possible ...

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Prevalence of Comorbidities, Overweight and Obesity in an International Sample of People with Multiple Sclerosis and Associations with Modifiable Lifestyle Factors

05-Feb-2016 | Claudia Helena Marck et al., PLoS ONE, 2016

by Claudia Helena Marck, Sandra Leanne Neate, Keryn Louise Taylor, Tracey Joy Weiland, George Alexander Jelinek Multiple sclerosis (MS) is a chronic neurological disorder, often affecting young people. Comorbid disorders such as depression, anxiety and hypertension are common and can affect ...

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Searching for cognitive enhancement in the Morris watermaze: Better and worse performance in D‐amino acid oxidase knockout (Dao‐/‐) mice

01-Feb-2016 | David Pritchett, Amy M. Taylor, Christopher Barkus, Sandra J. Engle, Nicholas J. Brandon, Trevor Sharp, Russell G. F ..., European Journal of Neuroscience, 2016

Abstract A common strategy when searching for cognitive enhancing drugs has been to target the NMDA receptor, given its putative role in synaptic plasticity and learning. Evidence in favour of this approach has come primarily from studies with rodents using behavioural assays like the Morris ...

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Neurochemical and behavioral indices of exercise reward are independent of exercise controllability

01-Feb-2016 | Jonathan J Herrera, Sofiya Fedynska, Parsa R Ghasem, Tyler Wieman, Peter J Clark, Nathan Gray, Esteban Loetz, Serge ..., European Journal of Neuroscience, 2016

Abstract Brain reward circuits are implicated in stress‐related psychiatric disorders. Exercise reduces the incidence of stress‐related disorders, but the contribution of exercise reward to stress resistance is unknown. Exercise‐induced stress resistance is independent of exercise ...

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Anxiety in Multiple Sclerosis: psychometric properties of the State‐Trait Anxiety Inventory

01-Feb-2016 | G. Santangelo, R. Sacco, M. Siciliano, A. Bisecco, G. Muzzo, R. Docimo, M. De Stefano, S. Bonavita, L. Lavorgna, G. ..., Acta Neurologica Scandinavica, 2016

Objective The aims of the present study were to examine psychometric properties of the Spielberger State‐Trait Anxiety Inventory (STAI‐Y‐1 and STAI‐Y‐2, respectively) in a Multiple Sclerosis (MS) population and to identify a cut‐off score to detect those MS patients with high level of state ...

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Neuropsychological phenotype and psychopathology in seven adult patients with Phelan‐McDermid syndrome: Implications for treatment strategy

29-Jan-2016 | Jos I.M. Egger, Renée J. Zwanenburg, Conny M.A. van Ravenswaaij‐Arts, Tjitske Kleefstra, Willem M.A. Verhoeven, Genes, Brain and Behavior, 2016

Abstract Phelan‐McDermid syndrome or 22q13.3 deletion syndrome is characterized by a variable degree of intellectual disability, impaired speech and language as well as social communicative skills, and mild dysmorphic features. The SHANK3 gene is thought to be a major contributor to the ...

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Passiflora incarnata L. Improves Spatial Memory, Reduces Stress, and Affects Neurotransmission in Rats

27-Jan-2016 | Katarzyna Jawna‐Zboińska, Kamilla Blecharz‐Klin, Ilona Joniec‐Maciejak, Adriana Wawer, Justyna Pyrzanowska, Agnieszk ..., Phytotherapy Research, 2016

Passiflora incarnata L. has been used as a medicinal plant in South America and Europe since the 16th century. Previous pharmacological studies focused mainly on the plant's sedative, anxiolytic, and anticonvulsant effects on the central nervous system and its supporting role in the treatment of ...

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[Report] Oxytocin-dependent consolation behavior in rodents

22-Jan-2016 | J. P. Burkett; E. Andari; Z. V. Johnson; D. C. Curry; F. B. M. de Waal; L. J. Young, Science , 2016

Consolation behavior toward distressed others is common in humans and great apes, yet our ability to explore the biological mechanisms underlying this behavior is limited by its apparent absence in laboratory animals. Here, we provide empirical evidence that a rodent species, the highly social ...

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