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938 Newest Publications about the topic anxiety


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Conditioning- and time-dependent increases in context fear and generalization [RESEARCH]

01-Jul-2016 | Andrew M. Poulos; Nehali Mehta; Bryan Lu; Dorsa Amir; Briana Livingston; Anthony Santarelli; Irina Zhuravka; Michael ..., Learning & Memory, 2016

A prominent feature of fear memories and anxiety disorders is that they endure across extended periods of time. Here, we examine how the severity of the initial fear experience influences incubation, generalization, and sensitization of contextual fear memories across time. Adult rats were ...


Cannabinoids reverse the effects of early stress on neurocognitive performance in adulthood [RESEARCH]

01-Jul-2016 | Shirley Alteba; Nachshon Korem; Irit Akirav, Learning & Memory, 2016

Early life stress (ES) significantly increases predisposition to psychopathologies. Cannabinoids may cause cognitive deficits and exacerbate the effects of ES. Nevertheless, the endocannabinoid system has been suggested as a therapeutic target for the treatment of stress- and anxiety-related ...


When Neutral Turns Significant: Brain dynamics of rapidly formed associations between neutral stimuli and emotional contexts

23-Jun-2016 | Carlos Ventura‐Bort, Andreas Löw, Julia Wendt, Florin Dolcos, Alfons O. Hamm, Mathias Weymar, European Journal of Neuroscience, 2016

Abstract The ability to associate neutral stimuli with motivationally relevant outcomes is an important survival strategy. In the present study, we used event‐related potentials (ERPs) to investigate brain dynamics of associative emotional learning when participants were confronted with ...


Psychophysiological Associations with Gastrointestinal Symptomatology in Autism Spectrum Disorder

20-Jun-2016 | Bradley J. Ferguson, Sarah Marler, Lily L. Altstein, Evon Batey Lee, Jill Akers, Kristin Sohl, Aaron McLaughlin, Kai ..., Autism Research, 2016

Autism spectrum disorder (ASD) is often accompanied by gastrointestinal disturbances, which also may impact behavior. Alterations in autonomic nervous system functioning are also frequently observed in ASD. The relationship between these findings in ASD is not known. We examined the relationship ...


Neuroendocrine Regulation of Anxiety: Beyond the HPA Axis

18-Jun-2016 | Amanda P. Borrow, Alexis M. Stranahan, Deborah Suchecki, Roberto Yunes, Journal of Neuroendocrinology, 2016

Abstract The central nervous system regulates and responds to endocrine signals, and this reciprocal relationship determines emotional processing and behavioural anxiety. While the hypothalamic‐pituitary‐adrenal axis (HPA) remains the best‐characterised system for this relationship, other ...


Crystal Genetics, Inc.

14-Jun-2016 | Bahram G Kermani, Personalized Medicine, 2016

Crystal Genetics, Inc. is an early-stage genetic test company, focused on achieving the highest possible clinical-grade accuracy and comprehensiveness for detecting germline (e.g., in hereditary cancer) and somatic (e.g., in early cancer detection) mutations. Crystal's mission is to significantly ...


A de novo microtriplication at 4q21.21‐q21.22 in a patient with a vascular malignant hemangioma, elongated sigmoid colon, developmental delay, and absence of speech

11-Jun-2016 | Igor N. Lebedev, Lyudmila P. Nazarenko, Nikolay A. Skryabin, Nadezhda P. Babushkina, Anna A. Kashevarova, American Journal of Medical Genetics Part A, 2016

The widespread application of array comparative genomic hybridization (aCGH) has provided new insights into the clinical significance of copy number variations (CNVs) in the human genome. Many microdeletion syndromes have recently been linked to corresponding reciprocal microduplication ...


Quality of life in adolescents and adults with CHARGE syndrome

08-Jun-2016 | Nancy Hartshorne, Alexandra Hudson, Jillian MacCuspie, Benjamin Kennert, Tasha Nacarato, Timothy Hartshorne, Kim Blake, American Journal of Medical Genetics Part A, 2016

Health‐related Quality of Life and the Impact of Childhood Neurologic Disability Scale were collected for 53 patients with CHARGE syndrome aged 13–39 years with a mean academic level of 4th grade. The most prevalent new and ongoing issues included bone health issues, sleep apnea, retinal ...


Sex Differences in Serum Markers of Major Depressive Disorder in the Netherlands Study of Depression and Anxiety (NESDA)

27-May-2016 | Jordan M. Ramsey; Jason D. Cooper; Mariska Bot; Paul C. Guest; Femke Lamers; Cynthia S. Weickert; Brenda W. J. H. Pe ..., PLoS ONE, 2016

by Jordan M. Ramsey, Jason D. Cooper, Mariska Bot, Paul C. Guest, Femke Lamers, Cynthia S. Weickert, Brenda W. J. H. Penninx, Sabine Bahn Women have a consistently higher prevalence of major depressive disorder (MDD) than men. Hypotheses implicating hypothalamic-pituitary -adrenal, -gonadal, ...


Cognitive flexibility deficits in a mouse model for the absence of full‐length dystrophin

24-May-2016 | Esther Remmelink, Annemieke Aartsma‐Rus, August B. Smit, Matthijs Verhage, Maarten Loos, Maaike van Putten, Genes, Brain and Behavior, 2016

Abstract Duchenne muscular dystrophy (DMD) is a progressive muscle‐wasting disorder, caused by mutations in the DMD gene and the resulting lack of dystrophin. The DMD gene has seven promoters, giving rise to multiple full‐length and shorter isoforms. Besides the expression of dystrophin in ...


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