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839 Newest Publications about the topic anxiety


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The Alzheimer's disease risk factor CD2AP maintains blood–brain barrier integrity

01-Dec-2015 | J. Nicholas Cochran; Travis Rush; Susan C. Buckingham; Erik D. Roberson, Human Molecular Genetics, 2015

CD2-associated protein (CD2AP) is a leading genetic risk factor for Alzheimer's disease, but little is known about the function of CD2AP in the brain. We studied CD2AP–/– mice to address this question. Because CD2AP–/– mice normally die by 6 weeks from nephrotic syndrome, we used mice that also ...


Safety profile of etifoxine A French pharmacovigilance survey

20-Nov-2015 | Judith Cottin, Aurore Gouraud, Marie‐Josèphe Jean‐Pastor, Anne Disson Dautriche, Charlène Boulay, Hélène Geniaux, Ma ..., Fundamental & Clinical Pharmacology, 2015

Abstract Etifoxine chlorhydrate is a benzoxazine derivative approved for the treatment of psychosomatic manifestations of anxiety since 1979. Previously labelled adverse drug reactions (ADRs) only include drowsiness, benign cutaneous reactions and acute hypersensitivity reactions. The ...


The basolateral amygdala γ‐aminobutyric acidergic system in health and disease

20-Nov-2015 | Eric M. Prager, Hadley C. Bergstrom, Gary H. Wynn, Maria F.M. Braga, Journal of Neuroscience Research, 2015

The brain comprises an excitatory/inhibitory neuronal network that maintains a finely tuned balance of activity critical for normal functioning. Excitatory activity in the basolateral amygdala (BLA), a brain region that plays a central role in emotion and motivational processing, is tightly ...


Continuous Exposure to Low-Dose-Rate Gamma Irradiation Reduces Airway Inflammation in Ovalbumin-Induced Asthma

20-Nov-2015 | Joong Sun Kim et al., PLoS ONE, 2015

by Joong Sun Kim, Yeonghoon Son, Min Ji Bae, Seung Sook Lee, Sun Hoo Park, Hae June Lee, Soong In Lee, Chang Geun Lee, Sung Dae Kim, Wol Soon Jo, Sung Ho Kim, In Sik Shin Although safe doses of radiation have been determined, concerns about the harmful effects of low-dose radiation persist. In ...


Maternal testosterone exposure increases anxiety-like behavior and impacts the limbic system in the offspring [Physiology]

17-Nov-2015 | Min Hu; Jennifer Elise Richard; Manuel Maliqueo; Milana Kokosar; Romina Fornes; Anna Benrick; Thomas Jansson; Claes ..., Proceedings of the National Academy of Sciences current issue, 2015

During pregnancy, women with polycystic ovary syndrome (PCOS) display high circulating androgen levels that may affect the fetus and increase the risk of mood disorders in offspring. This study investigated whether maternal androgen excess causes anxiety-like behavior in offspring mimicking ...


Olanzapine modulation of hepatic oxidative stress and inflammation in socially isolated rats

15-Nov-2015 | Author(s): Nevena Todorović, Nada Tomanović, Peter Gass, Dragana Filipović, European Journal of Pharmaceutical Science, 2015

Publication date: 1 January 2016 Source:European Journal of Pharmaceutical Sciences, Volume 81 Author(s): Nevena Todorović, Nada Tomanović, Peter Gass, Dragana Filipović Olanzapine, an atypical antipsychotic, is efficient in stress associated psychiatric diseases, but its effect on ...


De novo inbred heterozygous Zeb2/Sip1 mutant mice uniquely generated by germ-line conditional knockout exhibit craniofacial, callosal and behavioral defects associated with Mowat–Wilson syndrome

15-Nov-2015 | Tsuyoshi Takagi; Yuriko Nishizaki; Fumiko Matsui; Nobuaki Wakamatsu; Yujiro Higashi, Human Molecular Genetics, 2015

Mowat–Wilson syndrome (MOWS) is caused by de novo heterozygous mutation at ZEB2 (SIP1, ZFHX1B) gene, and exhibit moderate to severe intellectual disability (ID), a characteristic facial appearance, epilepsy and other congenital anomalies. Establishing a murine MOWS model is important, not only ...


Disability, anxiety and depression in patients with medication‐overuse headache in primary care – the BIMOH study

13-Nov-2015 | E. S. Kristoffersen, J. Straand, M. B. Russell, C. Lundqvist, European Journal of Neurology, 2015

Background and purpose Medication‐overuse headache (MOH) is common in the general population. Detoxification is the general treatment principle for MOH. The present paper is based on a study of a brief intervention (BI) for MOH in primary care. New data on headache disability and the Hospital ...


Vision problems in ischaemic stroke patients: effects on life quality and disability

13-Nov-2015 | K. M. Sand, G. Wilhelmsen, H. Næss, A. Midelfart, L. Thomassen, J. M. Hoff, European Journal of Neurology, 2015

Background and purpose Vision problems after cerebral infarction are an increasingly acknowledged problem. Our aim was to investigate the effect on quality of life and post‐stroke disability. Methods Patients admitted to the Stroke Unit, Department of Neurology, Haukeland University ...


Reduced Contextual Discrimination following Alcohol Consumption or MDMA Administration in Mice

13-Nov-2015 | Emily M. Johansson et al., PLoS ONE, 2015

by Emily M. Johansson, María S. García-Gutiérrez, María Moscoso-Castro, Jorge Manzanares, Olga Valverde The recreational drugs, alcohol and 3,4-Methylenedioxymethamphetamine (MDMA, “Ecstasy”) have both been shown to cause immune activation in vivo, and they are linked to cognitive impairment ...


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