07-06-2013 | C. M. Eddy, A. E. Cavanna, European Journal of Neurology, 2013

Background and purpose Coprolalia is a complex socially inappropriate vocal tic most frequently reported in the context of Tourette syndrome (TS) and widely portrayed as a cardinal characteristic of this condition throughout popular culture. This study investigated which clinical factors ...

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07-06-2013 | Stefanie M. Klampfl, Inga D. Neumann, Oliver J. Bosch, European Journal of Neuroscience, 2013

Abstract The brain corticotropin‐releasing factor (CRF) system triggers a variety of neuroendocrine and behavioural responses to stress. Whether maternal behaviour and emotionality in lactation are modulated by CRF has rarely been investigated. In the present study, we measured CRF mRNA ...

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07-06-2013 | Yebing Yang et al., PLoS ONE, 2013

by Yebing Yang, Yunfeng Sun, Ying Zhang, Yuan Jiang, Jingjing Tang, Xia Zhu, Danmin Miao Background Better understanding of acute stress responses is important for revision of DSM-5. However, the latent structure and relationship between different aspects of acute stress responses haven’t ...

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01-06-2013 | Roser Ufartes; Tomasz Schneider; Lena Sünke Mortensen; Camino de Juan Romero; Klaus Hentrich; Hendrik Knoetgen; Vadi ..., Human Molecular Genetics, 2013

Kv10.1 (Eag1), member of the Kv10 family of voltage-gated potassium channels, is preferentially expressed in adult brain. The aim of the present study was to unravel the functional role of Kv10.1 in the brain by generating knockout mice, where the voltage sensor and pore region of Kv10.1 ...

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23-05-2013 | Lukasz Piszczek, Kevin Schlax, Anna Wyrzykowska, Agnieszka Piszczek, Enrica Audero, Cornelius Thilo Gross, European Journal of Neuroscience, 2013

Abstract The neurotransmitter serotonin plays an important role in modulating diverse behavioral traits. Mice lacking the serotonin 1A receptor (Htr1a) show elevated avoidance of novel open spaces, suggesting that it has a role in modulating anxiety behavior. Htr1a is a Gαi‐coupled ...

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21-05-2013 | William Jarrold, Peter Mundy, Mary Gwaltney, Jeremy Bailenson, Naomi Hatt, Nancy McIntyre, Kwanguk Kim, Marjorie Sol ..., Autism Research, 2013

Impairments in social attention play a major role in autism, but little is known about their role in development after preschool. In this study, a public speaking task was used to study social attention, its moderators, and its association with classroom learning in elementary and secondary ...

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16-05-2013 | Caio Maximino, Bruna Puty, Karen Renata Matos Oliveira, Anderson Manoel Herculano, Genes, Brain and Behavior, 2013

Abstract The zebrafish leopard phenotype (leo) displays abnormal pigmentation and shows increased anxiety‐like behavior. The neurochemical changes associated with this anxious phenotype are not known. Here, we demonstrate that leo show increased anxiety‐like behavior in the light/dark box ...

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15-05-2013 | Letisha R Wyatt; Sean C Godar; Sheraz Khoja; Michael W Jakowec; Ronald L Alkana; Marco Bortolato; Daryl L Davies, Neuropsychopharmacology, 2013

Sociocommunicative and Sensorimotor Impairments in Male P2X4-Deficient Mice Neuropsychopharmacology advance online publication, May 15 2013. doi:10.1038/npp.2013.98 Authors: Letisha R Wyatt, Sean C Godar, Sheraz Khoja, Michael W Jakowec, Ronald L Alkana, Marco ...

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14-05-2013 | B. Esther Sportel et al., PLoS Neglected Tropical Diseases, 2013

by B. Esther Sportel, Eva de Hullu, Peter J. de Jong, Maaike H. Nauta Social anxiety is a common mental disorder among adolescents and is associated with detrimental long term outcomes. Therefore, this study investigated the efficacy of two possible early interventions for adolescent ...

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14-05-2013 | Marc Thill, Expert Review of Medical Devices, 2013

In breast conserving surgery, the tumor should be removed with a clean margin, a rim of healthy tissue surrounding. Failure to achieve clean margins in the initial surgery results in a re-excision procedure. Re-excision rates are reported as being 11–46% for invasive carcinoma and ductal ...

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