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706 Newest Publications about the topic anxiety


Functional characterization of FABP3, 5 and 7 gene variants identified in schizophrenia and autism spectrum disorder and mouse behavioral studies

15-12-2014 | Chie Shimamoto; Tetsuo Ohnishi; Motoko Maekawa; Akiko Watanabe; Hisako Ohba; Ryoichi Arai; Yoshimi Iwayama; Yasuko H ..., Human Molecular Genetics, 2014

Disturbances of lipid metabolism have been implicated in psychiatric illnesses. We previously reported an association between the gene for fatty acid binding protein 7 (FABP7) and schizophrenia. Furthermore, we identified and reported several rare non-synonymous polymorphisms of the ...


Pharmacological enhancement of mGluR5 facilitates contextual fear memory extinction [BRIEF COMMUNICATIONS]

01-12-2014 | Ferzin Sethna; Hongbing Wang, Learning & Memory, 2014

Behavioral exposure therapy, which involves extinction of the previously acquired fear, has been used to treat anxiety-related symptoms such as post-traumatic stress disorder. It has been hypothesized that proextinction pharmacotherapeutics may enhance the efficacy of exposure therapy. Systemic ...


Immune mediated disorders in women with a fragile X expansion and FXTAS

14-11-2014 | Isha Jalnapurkar, Nuva Rafika, Flora Tassone, Randi Hagerman, American Journal of Medical Genetics Part A, 2014

Premutation alleles in fragile X mental retardation 1 (FMR1) can cause the late‐onset neurodegenerative disorder, fragile X‐associated tremor ataxia syndrome (FXTAS) and/or the fragile X‐associated primary ovarian insufficiency in approximately 20% of heterozygotes. Heterozygotes of the FMR1 ...


Of ‘Disgrace’ and ‘Pain’ – Corticolimbic Interaction Patterns for Disorder-Relevant and Emotional Words in Social Phobia

14-11-2014 | Inga Laeger et al., PLoS ONE, 2014

by Inga Laeger, Christian Dobel, Britta Radenz, Harald Kugel, Kati Keuper, Annuschka Eden, Volker Arolt, Pienie Zwitserlood, Udo Dannlowski, Peter Zwanzger Limbic hyperactivation and an impaired functional interplay between the amygdala and the prefrontal cortex are discussed to go along with, ...


Depression and anxiety in COPD

13-11-2014 | International Journal of COPD, 2014

More than one third of individuals with chronic obstructive pulmonary disease (COPD) experience comorbid symptoms of depression and anxiety. This review aims to provide an overview of the burden of depression and anxiety in those with COPD and to outline the contemporary advances and challenges ...


Wfs1‐deficient animals have brain‐region‐specific changes of Na+, K+‐ATPase activity and mRNA expression of α1 and β1 subunits

11-11-2014 | S. Sütt, A. Altpere, R. Reimets, T. Visnapuu, M. Loomets, S. Raud, T. Salum, R. Mahlapuu, C. Kairane, M. Zilmer, E. ..., Journal of Neuroscience Research, 2014

Mutations in the WFS1 gene, which encodes the endoplasmic reticulum (ER) glycoprotein, cause Wolfram syndrome, a disease characterized by juvenile‐onset diabetes mellitus, optic atrophy, deafness, and different psychiatric abnormalities. Loss of neuronal cells and pancreatic β‐cells in Wolfram ...


A Transdiagnostic Community-Based Mental Health Treatment for Comorbid Disorders: Development and Outcomes of a Randomized Controlled Trial among Burmese Refugees in Thailand

11-11-2014 | Paul Bolton et al., PLoS Medicine, 2014

by Paul Bolton, Catherine Lee, Emily E. Haroz, Laura Murray, Shannon Dorsey, Courtland Robinson, Ana M. Ugueto, Judith Bass Background Existing studies of mental health interventions in low-resource settings have employed highly structured interventions delivered by non-professionals that ...


Individual differences in the peripheral immune system promote resilience versus susceptibility to social stress [Neuroscience]

11-11-2014 | Georgia E. Hodes; Madeline L. Pfau; Marylene Leboeuf; Sam A. Golden; Daniel J. Christoffel; Dana Bregman; Nicole Reb ..., Proceedings of the National Academy of Sciences current issue, 2014

Depression and anxiety disorders are associated with increased release of peripheral cytokines; however, their functional relevance remains unknown. Using a social stress model in mice, we find preexisting individual differences in the sensitivity of the peripheral immune system that predict and ...


More than seizures: improving the lives of people with refractory epilepsy

04-11-2014 | M. Mula, H. R. Cock, European Journal of Neurology, 2014

As captured by the proposed new definition, epilepsy is increasingly recognized as a disorder characterized not only by an enduring predisposition to recurrent seizures but explicitly also by the neurobiological, cognitive, psychological and social consequences of this condition. Further, both ...


Integrated Circuits and Molecular Components for Stress and Feeding: Implications for Eating Disorders

04-11-2014 | J. Andrew Hardaway, Nicole A. Crowley, Cynthia M. Bulik, Thomas L. Kash, Genes, Brain and Behavior, 2014

Abstract Eating disorders are complex brain disorders that afflict millions of individuals worldwide. The etiology of these diseases is not fully understood, but a growing body of literature suggests that stress and anxiety may play a critical role in their development. As our understanding of ...


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