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784 Newest Publications about the topic anxiety

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Associations of pain and depression with marital status in patients diagnosed with Parkinson's disease

03-Jul-2015 | A. Q. Rana, A. R. M. Qureshi, A. Mumtaz, I. Abdullah, A. Jesudasan, K. K. Hafez, M. A. Rana, Acta Neurologica Scandinavica, 2015

Background Depression and pain are significant clinical problems that are comorbid with Parkinson's disease (PD). However, the relationship of these variables with the marital status of patients with PD has not been explored in previous studies. Therefore, the goal of this study was to assess ...

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Inferences of Others' Competence Reduces Anticipation of Pain When under Threat

23-Jun-2015 | Ellen Tedeschi; Jochen Weber; Charlotte Prévost; Walter Mischel; Dean Mobbs, Journal of Cognitive Neuroscience, 2015

On a daily basis, we place our lives into the hands of strangers. From dentists to pilots, we make inferences about their competence to perform their jobs and consequently to keep us from harm. Here we explore whether the perceived competence of others can alter one's anticipation of pain. In two ...

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Neurodevelopmental variability in three young girls with a rare chromosomal disorder, 48, XXXX

18-Jun-2015 | Carole Samango‐Sprouse, Colleen Keen, Francie Mitchell, Teresa Sadeghin, Andrea Gropman, American Journal of Medical Genetics Part A, 2015

Fourty eight, XXXX is a rare chromosomal aneuploidy associated with neurocognitive deficits, speech and language disorders and executive dysfunction but the scarcity and variability of reported cases limit our understanding of the 48, XXXX phenotype. To our knowledge, this is the first study to ...

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On the role of NOS1 ex1f‐VNTR in ADHD—allelic, subgroup, and meta‐analysis

18-Jun-2015 | Heike Weber, Sarah Kittel‐Schneider, Julia Heupel, Lena Weißflog, Lindsey Kent, Florian Freudenberg, Aet Alttoa, Ant ..., American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, 2015

Attention deficit/ hyperactivity disorder (ADHD) is a heritable neurodevelopmental disorder featuring complex genetics with common and rare variants contributing to disease risk. In a high proportion of cases, ADHD does not remit during adolescence but persists into adulthood. Several studies ...

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[Report] C9ORF72 repeat expansions in mice cause TDP-43 pathology, neuronal loss, and behavioral deficits

05-Jun-2015 | Jeannie Chew; Tania F. Gendron; Mercedes Prudencio; Hiroki Sasaguri; Yong-Jie Zhang; Monica Castanedes-Casey; Chris ..., Science , 2015

The major genetic cause of frontotemporal dementia and amyotrophic lateral sclerosis is a G4C2 repeat expansion in C9ORF72. Efforts to combat neurodegeneration associated with “c9FTD/ALS” are hindered by a lack of animal models recapitulating disease features. We developed a mouse model to mimic ...

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Comparison of striatal dopamine transporter levels in chronic heroin‐dependent and methamphetamine‐dependent subjects

04-Jun-2015 | Jie Yuan, Xing Dang Liu, Mei Han, Rong Bin Lv, Yuan Kai Wang, Guang Ming Zhang, Yu Li, Addiction Biology, 2015

Abstract To compare the effects of heroin and methamphetamine (METH) addiction on dopamine transporters (DATs) in the same dose and duration, we assessed DAT levels in the striatum by 99mTc‐TRODAT‐1 single‐photon emission computed tomography (SPECT) brain images in people with heroin and METH ...

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Risk of Parkinson's disease following anxiety disorders: a nationwide population‐based cohort study

29-May-2015 | C.‐H. Lin, J.‐W. Lin, Y.‐C. Liu, C.‐H. Chang, R.‐M. Wu, European Journal of Neurology, 2015

Background and purpose Anxiety is potentially a pre‐motor symptom of Parkinson's disease (PD). Our aim was to investigate the association between anxiety and subsequent PD risk in a population‐based sample. Methods A total of 174776 participants, who were free of prior PD, dementia and ...

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Comparing genetic counselor's and patient's perceptions of needs in prenatal chromosomal microarray testing

20-May-2015 | Sarah A. Walser, Katherine S. Kellom, Steven C. Palmer, Barbara A. Bernhardt, Prenatal Diagnosis, 2015

Abstract Objective Chromosome microarray analysis (CMA) is poised to take a significant place in the prenatal setting given its increased yield over standard karyotyping, but concerns regarding ethical and counseling challenges remain, especially associated with the risk of uncertain and ...

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Developmental trajectories in 22q11.2 deletion syndrome

18-May-2015 | Ann Swillen, Donna McDonald‐McGinn, American Journal of Medical Genetics Part C: Seminars in Medical Genetics, 2015

Chromosome 22q11.2 deletion syndrome (22q11.2DS), a neurogenetic condition, is the most common microdeletion syndrome affecting 1 in 2,000–4,000 live births and involving haploinsufficiency of ∼50 genes resulting in a multisystem disorder. Phenotypic expression is highly variable and ranges ...

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Whole Genome Sequencing and Integrative Genomic Analysis Approach on Two 22q11.2 Deletion Syndrome Family Trios for Genotype to Phenotype Correlations

15-May-2015 | Jonathan H. Chung, Jinlu Cai, Barrie G. Suskin, Zhengdong Zhang, Karlene Coleman, Bernice E. Morrow, Human Mutation, 2015

ABSTRACT The 22q11.2 deletion syndrome (22q11DS) affects 1:4000 live births and presents with highly variable phenotype expressivity. In this study, we developed an analytical approach utilizing whole genome sequencing and integrative analysis to discover genetic modifiers. Our pipeline ...

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