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1,003 Newest Publications about the topic anxiety


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Behavioral mechanisms of context fear generalization in mice [RESEARCH]

01-Dec-2016 | Kylie A. Huckleberry; Laura B. Ferguson; Michael R. Drew, Learning & Memory, 2016

There is growing interest in generalization of learned contextual fear, driven in part by the hypothesis that mood and anxiety disorders stem from impaired hippocampal mechanisms of fear generalization and discrimination. However, there has been relatively little investigation of the behavioral ...


SSRI and SNRI use during pregnancy and the risk of persistent pulmonary hypertension of the newborn

22-Nov-2016 | Anick Bérard, Odile Sheehy, Jin‐Ping Zhao, Évelyne Vinet, Sasha Bernatsky, Michal Abrahamowicz, British Journal of Clinical Pharmacology, 2016

Aim Use of selective serotonin reuptake inhibitors (SSRIs) in late pregnancy may be associated with an increased risk of persistent pulmonary hypertension of the newborn (PPHN). Limited data are available on the risk of PPHN associated with serotonin norepinephrine reuptake inhibitors (SNRIs). ...


Attentional biases in patients with alcohol dependence: influence of coexisting psychopathology

17-Nov-2016 | Julia M.A. Sinclair, Matthew Garner, Sonja C. Pasche, Thomas B. Wood, David S. Baldwin, Human Psychopharmacology: Clinical and Experimental, 2016

Abstract Objective The effects of coexisting psychopathology on disorder‐specific attentional biases in patients with alcohol dependence are uncertain. We undertook a cross‐sectional study assessing attentional biases to alcohol‐, depression‐, and anxiety‐ related stimuli using the visual ...


Effectiveness of agomelatine on anhedonia in depressed patients: an outpatient, open‐label, real‐world study

17-Nov-2016 | Pedro Damian Gargoloff, Ricardo Corral, Luis Herbst, Miguel Marquez, Giovanni Martinotti, Pedro Rafael Gargoloff, Human Psychopharmacology: Clinical and Experimental, 2016

Abstract Objective The aim of this real‐world study was to evaluate the effect of agomelatine on anhedonia as primary endpoint in outpatients under treatment of major depressive episodes. Methods The study was an open‐label, multicenter, 8‐week phase IV trial. Two hundred fifty‐seven ...


Neuroligin 2 nonsense variant associated with anxiety, autism, intellectual disability, hyperphagia, and obesity

16-Nov-2016 | Daniel J. Parente, Caryn Garriga, Berivan Baskin, Ganka Douglas, Megan T. Cho, Gabriel C. Araujo, Marwan Shinawi, American Journal of Medical Genetics Part A, 2016

Neuroligins are post‐synaptic, cellular adhesion molecules implicated in synaptic formation and function. NLGN2 is strongly linked to inhibitory, GABAergic signaling and is crucial for maintaining the excitation‐inhibition balance in the brain. Disruption of the excitation‐inhibition balance is ...


Short‐term exposure to enriched environment rescues chronic stress‐induced impaired hippocampal synaptic plasticity, anxiety, and memory deficits

16-Nov-2016 | VenkannaRao Bhagya, Bettadapura N. Srikumar, Jayagopalan Veena, Byrathnahalli S. Shankaranarayana Rao, Journal of Neuroscience Research, 2016

Exposure to prolonged stress results in structural and functional alterations in the hippocampus including reduced long‐term potentiation (LTP), neurogenesis, spatial learning and working memory impairments, and enhanced anxiety‐like behavior. On the other hand, enriched environment (EE) has ...


Views of American OB/GYNs on the ethics of prenatal whole‐genome sequencing

16-Nov-2016 | Michelle J. Bayefsky, Amina White, Paul Wakim, Sara Chandros Hull, David Wasserman, Stephanie Chen, Benjamin E. Berkman, Prenatal Diagnosis, 2016

Abstract Objective Given public demand for genetic information, the potential to perform prenatal whole‐genome sequencing (PWGS) non‐invasively in the future, and decreasing costs of whole‐genome sequencing, it is likely that OB/GYN practice will include PWGS. The goal of this project was to ...


JNK1 controls adult hippocampal neurogenesis and imposes cell-autonomous control of anxiety behaviour from the neurogenic niche

15-Nov-2016 | H Mohammad; F Marchisella; S Ortega-Martinez; P Hollos; K Eerola; E Komulainen; N Kulesskaya; E Freemantle; V Fagerh ..., Molecular Psychiatry, 2016

JNK1 controls adult hippocampal neurogenesis and imposes cell-autonomous control of anxiety behaviour from the neurogenic niche Molecular Psychiatry advance online publication, November 15 2016. doi:10.1038/mp.2016.203 Authors: H Mohammad, F Marchisella, S Ortega-Martinez, P ...


Preliminary Identification of Coping Profiles Relevant to Surrogate Decision Making in the ICU

11-Nov-2016 | Jorie M. Butler; Eliotte L. Hirshberg; Ramona O. Hopkins; Emily L. Wilson; James F. Orme; Sarah J. Beesley; Kathryn ..., PLoS ONE, 2016

by Jorie M. Butler, Eliotte L. Hirshberg, Ramona O. Hopkins, Emily L. Wilson, James F. Orme, Sarah J. Beesley, Kathryn Kuttler, Samuel M. Brown Objective The Intensive Care Unit (ICU) is a stressful environment for families of critically ill patients and these individuals are at risk to develop ...


“They Can't Find Anything Wrong with Him, Yet”: Mothers’ experiences of parenting an infant with a prenatally diagnosed copy number variant (CNV)

07-Nov-2016 | Allison Werner‐Lin, Sarah Walser, Frances K. Barg, Barbara A. Bernhardt, American Journal of Medical Genetics Part A, 2016

Chromosome microarray (CMA) testing is used widely in prenatal settings. Some copy number variants (CNVs) detected using CMA are associated with variable or uncertain phenotype and/or possible neurocognitive involvement. Little is known about parenting an infant following such findings. ...


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