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969 Newest Publications about the topic anxiety


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The neural circuits of innate fear: detection, integration, action, and memorization [REVIEWS]

01-Oct-2016 | Bianca A. Silva; Cornelius T. Gross; Johannes Gräff, Learning & Memory, 2016

How fear is represented in the brain has generated a lot of research attention, not only because fear increases the chances for survival when appropriately expressed but also because it can lead to anxiety and stress-related disorders when inadequately processed. In this review, we summarize ...


Post-retrieval extinction in adolescence prevents return of juvenile fear [RESEARCH]

01-Oct-2016 | Carolyn E. Jones; Marie-H. Monfils, Learning & Memory, 2016

Traumatic experiences early in life can contribute to the development of mood and anxiety disorders that manifest during adolescence and young adulthood. In young rats exposed to acute fear or stress, alterations in neural development can lead to enduring behavioral abnormalities. Here, we used a ...


Graded fear generalization enhances the level of cfos‐positive neurons specifically in the basolateral amygdala

23-Sep-2016 | Abha K. Rajbhandari, Ruoyan Zhu, Cora Adling, Michael S. Fanselow, James A. Waschek, Journal of Neuroscience Research, 2016

Fear is an important emotional reaction in response to threatening stimuli and is important for survival. However, when fear occurs in inappropriate circumstances, it can lead to pathological conditions including an increased vulnerability for developing anxiety disorders such as posttraumatic ...


Neuroscience: Neurons' roles vary by sex

22-Sep-2016 | Nature, 2016

Neuroscience: Neurons' roles vary by sex Nature 537, 7621 (2016). doi:10.1038/537452d A class of nerve cell has different effects on social and anxiety-related behaviours in male and female mice in response to a hormone involved in social ...


Importance of a specialty clinic for individuals with fragile X syndrome

20-Sep-2016 | Jeannie Visootsak, Sharon A. Kidd, Tovi Anderson, Julia L. Bassell, Stephanie L. Sherman, Elizabeth M. Berry‐Kravis, American Journal of Medical Genetics Part A, 2016

Advances in human genetics have identified a significant number of genetic disorders associated with intellectual disability. As a result, appropriate clinical management of these affected individuals and their family members have become critical in addressing medical needs to improve quality ...


Oxytocin Modulates Semantic Integration in Speech Comprehension

20-Sep-2016 | Zheng Ye; Arjen Stolk; Ivan Toni; Peter Hagoort, Journal of Cognitive Neuroscience, 2016

Listeners interpret utterances by integrating information from multiple sources including word level semantics and world knowledge. When the semantics of an expression is inconsistent with his or her knowledge about the world, the listener may have to search through the conceptual space for ...


Neonatal maternal separation stress elicits lasting DNA methylation changes in the hippocampus of stress‐reactive Wistar Kyoto rats

19-Sep-2016 | Chelsea R. McCoy, Samir Rana, Sara Anne Stringfellow, Jeremy J. Day, J. Michael Wyss, Sarah M. Clinton, Ilan A. Kerman, European Journal of Neuroscience, 2016

Abstract Early‐life stress (ELS) can alter neurodevelopment in variable ways, ranging from producing deleterious outcomes to stress resilience. While most ELS studies focus on its harmful effects, recent work by our lab and others shows that ELS elicits positive effects in certain individuals. ...


M-Track: A New Software for Automated Detection of Grooming Trajectories in Mice

16-Sep-2016 | Sheldon L. Reeves; Kelsey E. Fleming; Lin Zhang; Annalisa Scimemi, PLoS Computational Biology, 2016

by Sheldon L. Reeves, Kelsey E. Fleming, Lin Zhang, Annalisa Scimemi Grooming is a complex and robust innate behavior, commonly performed by most vertebrate species. In mice, grooming consists of a series of stereotyped patterned strokes, performed along the rostro-caudal axis of the body. The ...


Factors Associated with Higher Reported Pain Levels in Patients with Chronic Musculoskeletal Pain: A Cross-Sectional, Correlational Analysis

16-Sep-2016 | Sang Jun Park; Duck Mi Yoon; Kyung Bong Yoon; Ji Ae Moon; Shin Hyung Kim, PLoS ONE, 2016

by Sang Jun Park, Duck Mi Yoon, Kyung Bong Yoon, Ji Ae Moon, Shin Hyung Kim Background Chronic musculoskeletal pain is highly prevalent, disabling, and costly, and has many negative effects on quality of life. The aim of this study was to investigate factors associated with higher reported pain ...


Long‐term effects of chronic nicotine on emotional and cognitive behaviors and hippocampus cell morphology in mice: comparisons of adult and adolescent nicotine exposure

13-Sep-2016 | Erica D. Holliday, Paul Nucero, Munir G. Kutlu, Chicora Oliver, Krista L. Connelly, Thomas J. Gould, Ellen M. Unterwald, European Journal of Neuroscience, 2016

Abstract Nicotine dependence is associated with increased risk for emotional, cognitive, and neurological impairments later in life. This study investigated the long‐term effects of nicotine exposure during adolescence and adulthood on measures of depression, anxiety, learning, and hippocampal ...


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