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1,092 Newest Publications about the topic anxiety


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Group genetic counseling: an alternate service delivery model in a high risk prenatal screening population

05-Sep-2017 | Mireille Cloutier, Lauren Gallagher, Claire Goldsmith, Salwa Akiki, Nick Barrowman, Shawna Morrison, Prenatal Diagnosis, 2017

Abstract Objective To address the growing demand for prenatal genetics services, group genetic counseling was explored as an alternative service delivery model for women with a positive prenatal screening result. Method Women were recruited from a prenatal genetics service and ...


Epigenetics at the crossroads between genes, environment and resilience in anxiety disorders

05-Sep-2017 | M. A. Schiele, K. Domschke, Genes, Brain and Behavior, 2017

The pathogenesis of anxiety disorders is multifactorial, involving complex interactions between biological factors, environmental influences, and psychological mechanisms. Recent advances have highlighted the role of epigenetics in bridging the gap between multiple contributing risk factors ...


Life situation 5 years after subarachnoid haemorrhage

04-Sep-2017 | H. C. Persson, L. Carlsson, K. S. Sunnerhagen, Acta Neurologica Scandinavica, 2017

Objectives Subarachnoid haemorrhage (SAH) has high mortality and morbidity among survivors. SAH mainly affects young people and may result in long‐term disabilities such as decreased Health‐related Quality of Life (HRQoL), mental health and cognitive function. The aim of this study was to ...


Persistent effects of acute stress on fear and drug-seeking in a novel model of the comorbidity between post-traumatic stress disorder and addiction [RESEARCH]

01-Sep-2017 | Christie L. Pizzimenti; Tom M. Navis; K. Matthew Lattal, Learning & Memory, 2017

Even following long periods of abstinence, individuals with anxiety disorders have high rates of relapse to drugs of abuse. Although many current models of relapse demonstrate effects of acute stress on drug-seeking, most of these studies examine stressful experiences that occur in close temporal ...


Interaction of induced anxiety and verbal working memory: influence of trait anxiety [RESEARCH]

01-Sep-2017 | Nilam Patel; Catherine Stoodley; Daniel S. Pine; Christian Grillon; Monique Ernst, Learning & Memory, 2017

This study examines the influence of trait anxiety on working memory (WM) in safety and threat. Interactions between experimentally induced anxiety and WM performance (on different cognitive loads) have been reported in healthy, nonanxious subjects. Differences in trait anxiety may moderate these ...


Characterization of the amplificatory effect of norepinephrine in the acquisition of Pavlovian threat associations [RESEARCH]

01-Sep-2017 | Lorenzo Díaz-Mataix; Walter T. Piper; Hillary C. Schiff; Clark H. Roberts; Vincent D. Campese; Robert M. Sears; Jose ..., Learning & Memory, 2017

The creation of auditory threat Pavlovian memory requires an initial learning stage in which a neutral conditioned stimulus (CS), such as a tone, is paired with an aversive one (US), such as a shock. In this phase, the CS acquires the capacity of predicting the occurrence of the US and therefore ...


Novelty and fear conditioning induced gene expression in high and low states of anxiety [RESEARCH]

01-Sep-2017 | Melanie P. Donley; Jeffrey B. Rosen, Learning & Memory, 2017

Emotional states influence how stimuli are interpreted. High anxiety states in humans lead to more negative, threatening interpretations of novel information, typically accompanied by activation of the amygdala. We developed a handling protocol that induces long-lasting high and low anxiety-like ...


Role of the bed nucleus of the stria terminalis in aversive learning and memory [REVIEWS]

01-Sep-2017 | Travis D. Goode; Stephen Maren, Learning & Memory, 2017

Surviving threats in the environment requires brain circuits for detecting (or anticipating) danger and for coordinating appropriate defensive responses (e.g., increased cardiac output, stress hormone release, and freezing behavior). The bed nucleus of the stria terminalis (BNST) is a critical ...


Breaking boundaries: optimizing reconsolidation-based interventions for strong and old memories [REVIEWS]

01-Sep-2017 | James W.B. Elsey; Merel Kindt, Learning & Memory, 2017

Recent research has demonstrated that consolidated memories can enter a temporary labile state after reactivation, requiring restabilization in order to persist. This process, known as reconsolidation, potentially allows for the modification and disruption of memory. Much interest in ...


Increased fear learning, spatial learning as well as neophobia in Rgs2−/− mice

28-Aug-2017 | A. Raab, S. Popp, K‐P. Lesch, M.J. Lohse, M. Fischer, J. Deckert, L. Hommers, Genes, Brain and Behavior, 2017

Abstract Anxiety disorders result from a complex interplay of genetic and environmental factors such as stress. On the level of cellular signaling, regulator of G protein signaling 2 (Rgs2) has been implicated in human and rodent anxiety. However, there is limited knowledge about the role of ...


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