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775 Newest Publications about the topic anxiety

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Whole Genome Sequencing and Integrative Genomic Analysis Approach on Two 22q11.2 Deletion Syndrome Family Trios for Genotype to Phenotype Correlations

15-May-2015 | Jonathan H. Chung, Jinlu Cai, Barrie G. Suskin, Zhengdong Zhang, Karlene Coleman, Bernice E. Morrow, Human Mutation, 2015

ABSTRACT The 22q11.2 deletion syndrome (22q11DS) affects 1:4000 live births and presents with highly variable phenotype expressivity. In this study, we developed an analytical approach utilizing whole genome sequencing and integrative analysis to discover genetic modifiers. Our pipeline ...

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Pain interference in youth with neurofibromatosis type 1 and plexiform neurofibromas and relation to disease severity, social‐emotional functioning, and quality of life

14-May-2015 | Pamela L. Wolters, Katherine M. Burns, Staci Martin, Andrea Baldwin, Eva Dombi, Mary Anne Toledo‐Tamula, William N. ..., American Journal of Medical Genetics Part A, 2015

The physical manifestations of neurofibromatosis type 1 (NF1) can cause chronic pain. This study investigated the impact of pain in youth with NF1 and plexiform neurofibromas (PNs) and its relationship to disease factors, social‐emotional functioning, and quality of life (QOL) within a ...

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Bullying Victimization, Parenting Stress, and Anxiety among Adolescents and Young Adults with Autism Spectrum Disorder

12-May-2015 | Jonathan A. Weiss, M. Catherine Cappadocia, Ami Tint, Debra Pepler, Autism Research, 2015

Bullying victimization is commonly associated with anxiety among individuals with and without Autism Spectrum Disorder (ASD), and both bullying victimization and anxiety are more prevalent among youth with ASD than in the general population. We explored individual and contextual factors that ...

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Functional Connectivity under Anticipation of Shock: Correlates of Trait Anxious Affect versus Induced Anxiety

11-May-2015 | Janine Bijsterbosch; Stephen Smith; Sonia J. Bishop, Journal of Cognitive Neuroscience, 2015

Sustained anxiety about potential future negative events is an important feature of anxiety disorders. In this study, we used a novel anticipation of shock paradigm to investigate individual differences in functional connectivity during prolonged threat of shock. We examined the correlates of ...

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Treatment-resistant depression: experience of the first repetitive transcranial magnetic stimulation clinic in the UK

08-May-2015 | Rafael Euba; Irina Panihhidina; Andy Zamar, Future Neurology, 2015

ABSTRACT  Aim: To report the clinical outcomes of 62 treatment-resistant depressed patients treated with repetitive transcranial magnetic stimulation (rTMS) in the first rTMS clinic in the UK during 2013. Materials & methods: Sixty-two treatment-resistant depressed patients (12 of them bipolar) ...

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Insight into Antagonist Binding and Induced Conformational Dynamics of Class B GPCR Corticotropin-Releasing Factor Receptor 1

07-May-2015 | Junli Xu; Zhonghua Wang; Pi Liu; Dongmei Li; Jianping Lin, Molecular BioSystems, 2015

The human corticotropin-releasing factor receptor type 1 (CRF1R) is a class B G-protein-coupled receptor (GPCR) which mediates the response to stress and has been considered as a drug target for depression and anxiety. Based on the CRF1R-antagonist crystal structure, we study the binding ...

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The predictive power of family history measures of alcohol and drug problems and internalizing disorders in a college population

06-May-2015 | Kenneth S Kendler, Alexis Edwards, John Myers, Seung Bin Cho, Amy Adkins, Danielle Dick, American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, 2015

A family history (FH) of psychiatric and substance use problems is a potent risk factor for common internalizing and externalizing disorders. In a large web‐based assessment of mental health in college students, we developed a brief set of screening questions for a FH of alcohol problems (AP), ...

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The amplification of risk in experimental diffusion chains [Psychological and Cognitive Sciences]

05-May-2015 | Mehdi Moussaïd; Henry Brighton; Wolfgang Gaissmaier, Proceedings of the National Academy of Sciences current issue, 2015

Understanding how people form and revise their perception of risk is central to designing efficient risk communication methods, eliciting risk awareness, and avoiding unnecessary anxiety among the public. However, public responses to hazardous events such as climate change, contagious outbreaks, ...

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[Report] Selective information routing by ventral hippocampal CA1 projection neurons

01-May-2015 | S. Ciocchi; J. Passecker; H. Malagon-Vina; N. Mikus; T. Klausberger, Science , 2015

The hippocampus computes diverse information involving spatial memory, anxiety, or reward and directly projects to several brain areas. Are different computations transmitted to all downstream targets uniformly, or does the hippocampus selectively route information according to content and target ...

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Evidence‐to‐practice gaps in the management of community‐dwelling Australian patients with ischaemic heart disease

29-Apr-2015 | O. Schmid, L. Chalmers, L. Bereznicki, Journal of Clinical Pharmacy and Therapeutics, 2015

Summary What is known and objective Ischaemic heart disease (IHD) is a major cause of death in developed countries. Patients with IHD are at greater risk of subsequent myocardial infarction (MI). International studies suggest that guideline recommended therapies proven to reduce this risk ...

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