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137 Newest Publications about the topic adult stem cells

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Bone morphogenetic protein‐2, ‐6, and ‐7 differently regulate osteogenic differentiation of human periodontal ligament stem cells

13-07-2013 | Sema S. Hakki, Buket Bozkurt, Erdogan E. Hakki, Seyit Ali Kayis, Gizem Turac, Irem Yilmaz, Erdal Karaoz, Journal of Biomedical Materials Research Part B: Applied Biomaterials, 2013

Abstract The utility of adult stem cells for bone regeneration may be an attractive alternative in the treatment of extensive injury, congenital malformations, or diseases causing large bone defects. To create an environment that is supportive of bone formation, signals from molecules such as ...

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Character comparison of abdomen‐derived and eyelid‐derived mesenchymal stem cells

22-05-2013 | S.‐H. Kim, S. H. Bang, S. A. Park, S. Y. Kang, K. D. Park, I. U. Oh, S. H. Yoo, H. Kim, C.‐H. Kim, S. Y. Baek, Cell Proliferation, 2013

Abstract Objectives While most human adipose tissues, such as those located in the abdomen, hip and thigh, are of mesodermal origin, adipose tissues located in the face are of ectodermal origin. The present study has compared stem cell‐related features of abdomen‐derived adult stem cells ...

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How stem cells speak with host immune cells in inflammatory brain diseases

30-04-2013 | Stefano Pluchino, Chiara Cossetti, Glia, 2013

Advances in stem cell biology have raised great expectations that diseases and injuries of the central nervous system (CNS) may be ameliorated by the development of non‐hematopoietic stem cell medicines. Yet, the application of adult stem cells as CNS therapeutics is challenging and the ...

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Dental follicle progenitor cells responses to Porphyromonas gingivalis LPS

08-04-2013 | Kyriaki Chatzivasileiou, Cornelia A. Lux, Gustav Steinhoff, Hermann Lang, Journal of Cellular and Molecular Medicine, 2013

Abstract Periodontitis is a bacterially induced chronic inflammatory disease. Dental follicle progenitor cells (DFPCs) have been proposed as biological graft for periodontal regenerative therapies. The potential impact of bacterial toxins on DFPCs properties is still poorly understood. The aim ...

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Expression of Oct4 in human embryonic stem cells is dependent on nanotopographical configuration

07-04-2013 | Acta Biomaterialia, 2013

May 2013 Publication year: 2013Source:Acta Biomaterialia, Volume 9, Issue 5 The fate of adult stem cells can be influenced by physical cues, including nanotopography. However, the response of human embryonic stem cells (hESCs) to dimensionally well-defined nanotopography is unknown. ...

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Priming mesenchymal stem cells boosts stem cell therapy to treat myocardial infarction

14-03-2013 | Juliana L. Carvalho, Vinicius B. A. Braga, Marcos B. Melo, Ana Carolina D. A. Campos, Maira S. Oliveira, Dawidson A. ..., Journal of Cellular and Molecular Medicine, 2013

Abstract Cardiovascular diseases are the number one cause of death globally and are projected to remain the single leading cause of death. Treatment options abounds, although efficacy is limited. Recent studies attribute discrete and ephemeral benefits to adult stem cell therapies, indicating ...

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DNA damage in stem cells activates p21, inhibits p53, and induces symmetric self-renewing divisions [Cell Biology]

05-03-2013 | Alessandra Insinga; Angelo Cicalese; Mario Faretta; Barbara Gallo; Luisa Albano; Simona Ronzoni; Laura Furia; Andrea ..., Proceedings of the National Academy of Sciences current issue, 2013

DNA damage leads to a halt in proliferation owing to apoptosis or senescence, which prevents transmission of DNA alterations. This cellular response depends on the tumor suppressor p53 and functions as a powerful barrier to tumor development. Adult stem cells are resistant to DNA damage-induced ...

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[Cell Signaling] Wnt Signaling in Skin Development, Homeostasis, and Disease

01-02-2013 | Xinhong Lim; Roel Nusse, CSH Perspectives, 2013

The skin and its appendages constitute the largest organ of the body. Its stratified epithelia offer protection from environmental stresses such as dehydration, irradiation, mechanical trauma, and pathogenic infection, whereas its appendages, like hair and sebaceous glands, help regulate body ...

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MicroRNAs Regulate Tumor Angiogenesis Modulated by Endothelial Progenitor Cells

01-01-2013 | Prue N. Plummer; Ruth Freeman; Ryan J. Taft; Jelena Vider; Michael Sax; Brittany A. Umer; Dingcheng Gao; Christopher ..., Cancer Research, 2013

Bone marrow–derived endothelial progenitor cells (EPC) contribute to the angiogenesis-dependent growth of tumors in mice and humans. EPCs regulate the angiogenic switch via paracrine secretion of proangiogenic growth factors and by direct luminal incorporation into sprouting nascent vessels. ...

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Identity of tendon stem cells – How much do we know?

28-12-2012 | Pauline Po Yee Lui, Journal of Cellular and Molecular Medicine, 2012

Abstract Tendon stem cells are multi‐potent adult stem cells with broad differentiation plasticity that render them of great importance in cell‐based therapies for the repair of tendons. We called them tendon‐derived stem cells (TDSCs) to indicate the tissue origin from which the stem cells ...

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