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34,056 Newest Publications of WILEY

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Influence of abiotic variables on culturable yeast diversity in two distinct Alpine glaciers

16-06-2013 | Benedetta Turchetti, Marta Goretti, Eva Branda, Guglielmina Diolaiuti, Carlo D'Agata, Claudio Smiraglia, Andrea Onof ..., FEMS Microbiology Ecology, 2013

Summary The influence of some abiotic variables (pH, dry weight, organic carbon, nitrogen and phosphorous) on culturable yeast diversity in two distinct, but adjacent Alpine glaciers (glacier du Géant, France, and Miage glacier, Italy) was investigated. In all, 682 yeast strains were ...

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pH dominates variation in tropical soil archaeal diversity and community structure

16-06-2013 | Binu M. Tripathi, Mincheol Kim, Ang Lai‐Hoe, Nor Aini Ab Shukor, Raha Abdul Rahim, Rusea Go, Jonathan M. Adams, FEMS Microbiology Ecology, 2013

Abstract Little is known of the factors influencing soil archaeal community diversity and composition in the tropics. We sampled soils across a range of forest and non‐forest environments in the equatorial tropics of Malaysia, covering a wide range of pH values. DNA was PCR‐amplified for ...

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Genetic variation in the PNPLA3 gene and hepatocellular carcinoma in USA: Risk and prognosis prediction

15-06-2013 | Manal M. Hassan, Ahmed Kaseb, Carol J. Etzel, Hashem El‐Serag, Margaret R. Spitz, Ping Chang, Katherine S. Hale, Mei ..., Molecular Carcinogenesis, 2013

Abstract Nonalcoholic fatty liver disease (NAFLD) is an emerging epidemic with high prevalence in Western countries. Genome‐wide association studies had reported that a variation in the patatin‐like phospholipase domain containing 3 (PNPLA3) gene is associated with high susceptibility to ...

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Health related quality of life in patients recently diagnosed with multiple sclerosis

15-06-2013 | G. Klevan, C. O. Jacobsen, J. H. Aarseth, K.‐M. Myhr, H. Nyland, S. Glad, K. Lode, N. Figved, J. P. Larsen, E. Farbu, Acta Neurologica Scandinavica, 2013

Objective To describe a representative population of patients recently diagnosed with MS in terms of both motor and non‐motor disability. In particular we wanted to examine the HRQoL in this population to get a better understanding of what impact various clinical features have on the ...

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US nationwide trends in carotid revascularization: is there a clinical opportunity cost associated with the introduction of novel medical devices?

15-06-2013 | J. H. Choi, J. Pile‐Spellman, J. L. Brisman, Acta Neurologica Scandinavica, 2013

Objectives Nationwide practice patterns during the implementation of novel technology, such as carotid angioplasty and stenting (CAS) and embolic protection devices (EPD), and the clinical impact thereof have received less attention. Methods The Nationwide Inpatient Sample, ...

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Safety and tolerability of zonisamide in elderly patients with epilepsy

15-06-2013 | E. Trinka, L. Giorgi, A. Patten, J. Segieth, Acta Neurologica Scandinavica, 2013

Objectives To assess the safety/tolerability of zonisamide in elderly patients. Materials & methods A pooled analysis of clinical study data from elderly (≥65years) patients receiving add‐on/monotherapy zonisamide for partial seizures was compared with pooled adult (18–65years) ...

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The progress of cognitive decline in newly diagnosed MS patients

15-06-2013 | E. Hankomäki, J. Multanen, E. Kinnunen, P. Hämäläinen, Acta Neurologica Scandinavica, 2013

Objectives Cognitive impairment occurs in multiple sclerosis already in the early stages of the disease. Less is known about the evolution of cognitive decline, especially in newly diagnosed MS patients. The results of existing studies are contradictory in that both cognitive preservation ...

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Native cysteine residues are dispensable for the structure and function of all five yeast mitotic septins

15-06-2013 | Natalia de Val, Michael A. McMurray, Lisa H. Lam, Chris C.‐S. Hsiung, Aurélie Bertin, Eva Nogales, Jeremy Thorner, Proteins: Structure, Function, and Bioinformatics, 2013

ABSTRACT Budding yeast septins assemble into hetero‐octamers and filaments required for cytokinesis. Solvent‐exposed cysteine (Cys) residues provide sites for attaching substituents useful in assessing assembly kinetics and protein interactions. To introduce Cys at defined locations, ...

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DockTrina: Docking triangular protein trimers

15-06-2013 | Petr Popov, David W. Ritchie, Sergei Grudinin, Proteins: Structure, Function, and Bioinformatics, 2013

ABSTRACT In spite of the abundance of oligomeric proteins within a cell, the structural char‐acterization of protein‐protein interactions is still a challenging task. In particular, many of these interactions involve heteromeric complexes, which are relatively difficult to determine ...

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Two weeks of pretreatment with escitalopram facilitates extinction learning in healthy individuals

15-06-2013 | Eric Bui, Scott P. Orr, Ryan J. Jacoby, Aparna Keshaviah, Nicole J. LeBlanc, Mohammed R. Milad, Mark H. Pollack, Nao ..., Human Psychopharmacology: Clinical and Experimental, 2013

Objective We aimed to examine whether pretreatment with escitalopram would be associated with reduced fear acquisition and enhanced extinction learning in a fear conditioning paradigm, compared with placebo. Methods Healthy volunteers were randomized in double‐blind fashion, to ...

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