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5,013 Newest Publications of Oxford University Press

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Organomagnesium suppresses inflammation-associated colon carcinogenesis in male Crj: CD-1 mice

01-02-2013 | Toshiya Kuno; Yuichiro Hatano; Hiroyuki Tomita; Akira Hara; Yoshinobu Hirose; Akihiro Hirata; Hideki Mori; Masaru Te ..., Carcinogenesis , 2013

Magnesium (Mg) deficiency increases genomic instability and Mg intake has been reported to be inversely associated with a risk of colorectal cancer (CRC). This study was designed to determine whether organo-Mg in drinking water suppresses inflammation-associated colon carcinogenesis in mice. ...

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Light Detection and Signal Transduction in the BLUF Photoreceptors

01-02-2013 | Shinji Masuda, Plant and Cell Physiology, 2013

BLUF (sensor of blue light using FAD) domain-containing proteins are one of three types of flavin-binding, blue-light-sensing proteins found in many bacteria and some algae. The other types of blue-light-sensing proteins are the cryptochromes and the light, oxygen, voltage (LOV) ...

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Effects of limiting energy availability via diet and physical activity on mammalian target of rapamycin-related signaling in rat mammary carcinomas

01-02-2013 | Weiqin Jiang; Zongjian Zhu; Henry J. Thompson, Carcinogenesis , 2013

This study evaluated how different approaches to limiting energy availability (LEA) by 15% affected mammalian target of rapamycin (mTOR)-related signaling in mammary carcinomas. Female Sprague Dawley rats, injected with 50mg 1-methyl-1-nitrosourea per kilogram body weight, were randomized to ...

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Enhancing Sucrose Synthase Activity Results in Increased Levels of Starch and ADP-Glucose in Maize (Zea mays L.) Seed Endosperms

01-02-2013 | Jun Li; Edurne Baroja-Fernández; Abdellatif Bahaji; Francisco José Muñoz; Miroslav Ovecka; Manuel Montero; María Ter ..., Plant and Cell Physiology, 2013

Sucrose synthase (SuSy) is a highly regulated cytosolic enzyme that catalyzes the conversion of sucrose and a nucleoside diphosphate into the corresponding nucleoside diphosphate glucose and fructose. In cereal endosperms, it is widely assumed that the stepwise reactions of SuSy, UDPglucose ...

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Histone deacetylase inhibitor suberoylanilide hydroxamic acid suppresses the pro-oncogenic effects induced by hepatitis B virus pre-S2 mutant oncoprotein and represents a potential chemopreventive agent in high-risk chronic HBV patients

01-02-2013 | Yi-Hsuan Hsieh; Ih-Jen Su; Chia-Jui Yen; Ting-Fen Tsai; Hung-Wen Tsai; Han-Ni Tsai; Yu-Jun Huang; Yen-Yu Chen; Yu-Li ..., Carcinogenesis , 2013

Chronic hepatitis B virus (HBV) infection is the major cause of hepatocellular carcinoma (HCC). The pre-S2 mutant large HBV surface antigen (LHBS) in type II ground glass hepatocytes (GGHs) has been recognized as an emerging viral oncoprotein; it directly interacts with the c-Jun activation ...

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Orchidstra: An Integrated Orchid Functional Genomics Database

01-02-2013 | Chun-lin Su; Ya-Ting Chao; Shao-Hua Yen; Chun-Yi Chen; Wan-Chieh Chen; Yao-Chien Alex Chang; Ming-Che Shih, Plant and Cell Physiology, 2013

A specialized orchid database, named Orchidstra (URL: http://orchidstra.abrc.sinica.edu.tw), has been constructed to collect, annotate and share genomic information for orchid functional genomics studies. The Orchidaceae is a large family of Angiosperms that exhibits extraordinary ...

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Fine-mapping of the 6q25 locus identifies a novel SNP associated with breast cancer risk in African–American women

01-02-2013 | Edward A. Ruiz-Narváez; Lynn Rosenberg; Song Yao; Charles N. Rotimi; Adrienne L. Cupples; Elisa V. Bandera; Christin ..., Carcinogenesis , 2013

The rs2046210 single nucleotide polymorphism (SNP) in the 6q25.1 region was identified in a breast cancer genome-wide association study of Chinese women. The SNP has been replicated in European ancestry populations, but replication efforts have failed in African ancestry populations. We ...

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UniVIO: A Multiple Omics Database with Hormonome and Transcriptome Data from Rice

01-02-2013 | Toru Kudo; Kenji Akiyama; Mikiko Kojima; Nobue Makita; Tetsuya Sakurai; Hitoshi Sakakibara, Plant and Cell Physiology, 2013

Plant hormones play important roles as signaling molecules in the regulation of growth and development by controlling the expression of downstream genes. Since the hormone signaling system represents a complex network involving functional cross-talk through the mutual regulation of signaling ...

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Recruitment of NCOR1 to VDR target genes is enhanced in prostate cancer cells and associates with altered DNA methylation patterns

01-02-2013 | Craig L. Doig; Prashant K. Singh; Vineet K. Dhiman; James L. Thorne; Sebastiano Battaglia; Michelle Sobolewski; Orla ..., Carcinogenesis , 2013

The current study investigated transcriptional distortion in prostate cancer cells using the vitamin D receptor (VDR) as a tool to examine how epigenetic events driven by corepressor binding and CpG methylation lead to aberrant gene expression. These relationships were investigated in the ...

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OrchidBase 2.0: Comprehensive Collection of Orchidaceae Floral Transcriptomes

01-02-2013 | Wen-Chieh Tsai; Chih-Hsiung Fu; Yu-Yun Hsiao; Yueh-Min Huang; Li-Jun Chen; Meina Wang; Zhong-Jian Liu; Hong-Hwa Chen, Plant and Cell Physiology, 2013

Both floral development and evolutionary trends of orchid flowers have long attracted the interest of biologists. However, expressed sequences derived from the flowers of other orchid subfamilies are still scarce except for a few species in Epidendroideae. In order to broadly increase our ...

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