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2,360 Newest Publications of Elsevier
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Rapid isothermal substrate microfabrication of biocompatible thermoplastic elastomer for cellular contact guidance
16-02-2011 | Maxime D., Guillemette , Emmanuel, Roy , François A., Auger , Teodor, Veres, Acta Biomaterialia, 2011
The use of microstructured substrates to study and influence cell orientation, which play an important role in tissue functionality, has been of great interest lately. Silicon and poly (dimethylsiloxane) substrates have been typically used, but long processing time and exogenous protein ...
Flexural Characterization of Cell Encapsulated PEGDA Hydrogels with Applications for Tissue Engineered Heart Valves
16-02-2011 | Christopher A., Durst , Michael P., Cuchiara , Elizabeth G., Mansfield , Jennifer L., West , K. Jane, Grande-Allen, Acta Biomaterialia, 2011
The limitations of the current clinical options for valve replacements inspire development of enabling technologies to create a tissue engineered heart valve (TEHV). Poly(ethylene glycol) diacrylate (PEGDA) hydrogel scaffolds permit greater biological and biomechanical customization than do ...
Analysis of the In Vitro Swelling Behavior of PVA Hydrogels in Osmotic Pressure Solution For Soft Tissue Replacement
16-02-2011 | Julianne L., Holloway , Kara L., Spiller , Anthony M., Lowman , Giuseppe R., Palmese, Acta Biomaterialia, 2011
An osmotic solution was used to evaluate poly(vinyl alcohol) (PVA) hydrogels as potential nondegradable soft tissue replacements in vitro. Osmotic solutions were necessary in order to mimic the swelling pressure observed in vivo for soft tissues present in load bearing joints. In vitro ...
A novel approach for analyzing glass-transition temperature vs. composition patterns: application to pharmaceutical compound+polymer systems
15-02-2011 | Ioannis M., Kalogeras, European Journal of Pharmaceutical Science, 2011
In medicine, polymer-based materials are commonly used as excipients of poorly water-soluble drugs. The success of the encapsulation, as well as the physicochemical stability of the products, is often reflected on their glass transition temperature (Tg) vs. composition (w) dependencies. The ...
Thermoresponsive polymeric radionuclide delivery system - an injectable brachytherapy
15-02-2011 | Martin, Hruby , Pavla, Pouckova , Marie, Zadinova , Jan, Kucka , Ondrej, Lebeda, European Journal of Pharmaceutical Science, 2011
Brachytherapy is of increasing popularity in clinical oncology for the local therapy of solid tumors due to high radiation doses delivered to malignant tissue while keeping the whole-body radiation burden low. Pronounced dose-dependent tumor growth reduction was achieved by single dose of ...
Biocompatibility of magnesium phosphate minerals and their stability under physiological conditions
15-02-2011 | Faleh, Tamimi , Damien, Le Nihouannen , David C., Bassett , Suzette, Ibasco , Uwe, Gbureck , ..., Acta Biomaterialia, 2011
Magnesium phosphates such as newberyite (MgHPO4.3H2O) are formed in vivo and are known to be biodegradable and non toxic after implantation. Indeed magnesium apatites have been shown to support osteoblast differentiation and function, and bone formation can occur around metallic magnesium ...
Effect of pore structures of bioactive glass balls on biocompatibility in vitro and in vivo
13-02-2011 | Hui-Suk, Yun , Jin-Woo, Park , Sang-Hyun, Kim , Youn-Jeong, Kim , Je-Hee, Jang, Acta Biomaterialia, 2011
We prepared porous bioactive glass (BG) balls with various pore architectures using a modified version of a polymer templating technique which is generally used for the synthesis of mesoporous BG. Sol-gel derived porous BG is an excellent candidate as a graft material for bone tissue ...
A new insight in the dissociating effect of strontium on bone resorption and formation
12-02-2011 | Julien, Braux , Frédéric, Velard , Christine, Guillaume , Sylvie, Bouthors , Edouard, Jallot , ..., Acta Biomaterialia, 2011
Calcium phosphates are widely used as biomaterials and strontium (Sr) is known to have abilities to modify the bone balance toward osteosynthesis. In the present study, we investigated the capacities of our Sr-substituted sol-gel calcium phosphate to modify genes expression and proteins ...
Mesoporous bioactive glasses: mechanical reinforcement by means of a biomimetic process
12-02-2011 | D., Arcos , M., Vila , A., López-Noriega , F., Rossignol , E., Champion , ..., Acta Biomaterialia, 2011
Mesoporous bioactive glasses (MBGs) constitute a new family of bioceramics with the fastest in vitro bioactivity studied so far. In this work, pieces with the composition 85 SiO2-10 CaO-5 P2O5 (% mol) were prepared as MBG and also by the conventional sol-gel method. After in vitro tests in ...
In Vitro and In Vivo Degradation Profile of Aliphatic Polyesters Subjected to Electron Beam Sterilization
12-02-2011 | S., Dånmark , A., Finne-Wistrand , K., Schander , M., Hakkarainen , K., Arvidson , ..., Acta Biomaterialia, 2011
Degradation characteristics in response to electron beam sterilization of designed and biodegradable aliphatic polyesters scaffolds are relevant for clinical successful synthetic graft tissue regeneration. Scaffold degradation in vitro and in vivo weredocumented and correlated to the ...
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