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1,585 Newest Publications in plos pathogens
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Host Defense and Recruitment of Foxp3+ T Regulatory Cells to the Lungs in Chronic Mycobacterium tuberculosis Infection Requires Toll-like Receptor 2
13-06-2013 | Amanda McBride et al., PLoS Pathogens, 2013
by Amanda McBride, Jill Konowich, Padmini Salgame Acute resistance to low dose M. tuberculosis (Mtb) infection is not dependent on Toll-like receptor (TLR) 2. However, whether TLR2 contributes to resistance in chronic Mtb infection has remained uncertain. Here we report that, following low ...
Bacterial Cytolysin during Meningitis Disrupts the Regulation of Glutamate in the Brain, Leading to Synaptic Damage
13-06-2013 | Carolin Wippel et al., PLoS Pathogens, 2013
by Carolin Wippel, Jana Maurer, Christina Förtsch, Sabrina Hupp, Alexandra Bohl, Jiangtao Ma, Timothy J. Mitchell, Stephanie Bunkowski, Wolfgang Brück, Roland Nau, Asparouh I. Iliev Streptococcus pneumoniae (pneumococcal) meningitis is a common bacterial infection of the brain. The ...
Sub-Inhibitory Concentrations of Human α-defensin Potentiate Neutralizing Antibodies against HIV-1 gp41 Pre-Hairpin Intermediates in the Presence of Serum
13-06-2013 | Lusine Demirkhanyan et al., PLoS Pathogens, 2013
by Lusine Demirkhanyan, Mariana Marin, Wuyuan Lu, Gregory B. Melikyan Human defensins are at the forefront of the host responses to HIV and other pathogens in mucosal tissues. However, their ability to inactivate HIV in the bloodstream has been questioned due to the antagonistic effect of ...
Combination of DNA Prime – Adenovirus Boost Immunization with Entecavir Elicits Sustained Control of Chronic Hepatitis B in the Woodchuck Model
13-06-2013 | Anna D. Kosinska et al., PLoS Pathogens, 2013
by Anna D. Kosinska, Ejuan Zhang, Lena Johrden, Jia Liu, Pia L. Seiz, Xiaoyong Zhang, Zhiyong Ma, Thekla Kemper, Melanie Fiedler, Dieter Glebe, Oliver Wildner, Ulf Dittmer, Mengji Lu, Michael Roggendorf A potent therapeutic T-cell vaccine may be an alternative treatment of chronic ...
Efficient Sensing of Infected Cells in Absence of Virus Particles by Blasmacytoid Dendritic Cells Is Blocked by the Viral Ribonuclease Erns
13-06-2013 | Sylvie Python et al., PLoS Pathogens, 2013
by Sylvie Python, Markus Gerber, Rolf Suter, Nicolas Ruggli, Artur Summerfield Plasmacytoid dendritic cells (pDC) have been shown to efficiently sense HCV- or HIV-infected cells, using a virion-free pathway. Here, we demonstrate for classical swine fever virus, a member of the ...
Developing Models of Disease Transmission: Insights from Ecological Studies of Insects and Their Baculoviruses
13-06-2013 | Bret D. Elderd, PLoS Pathogens, 2013
by Bret D. Elderd
Influenza Virus Reassortment Occurs with High Frequency in the Absence of Segment Mismatch
13-06-2013 | Nicolle Marshall et al., PLoS Pathogens, 2013
by Nicolle Marshall, Lalita Priyamvada, Zachary Ende, John Steel, Anice C. Lowen Reassortment is fundamental to the evolution of influenza viruses and plays a key role in the generation of epidemiologically significant strains. Previous studies indicate that reassortment is restricted by ...
Glycan Masking of Plasmodium vivax Duffy Binding Protein for Probing Protein Binding Function and Vaccine Development
13-06-2013 | Sowmya Sampath et al., PLoS Pathogens, 2013
by Sowmya Sampath, Chris Carrico, Joel Janes, Sairam Gurumoorthy, Claire Gibson, Martin Melcher, Chetan E. Chitnis, Ruobing Wang, William R. Schief, Joseph D. Smith Glycan masking is an emerging vaccine design strategy to focus antibody responses to specific epitopes, but it has mostly ...
An Apicoplast Localized Ubiquitylation System Is Required for the Import of Nuclear-encoded Plastid Proteins
13-06-2013 | Swati Agrawal et al., PLoS Pathogens, 2013
by Swati Agrawal, Duk-Won D. Chung, Nadia Ponts, Giel G. van Dooren, Jacques Prudhomme, Carrie F. Brooks, Elisadra M. Rodrigues, John C. Tan, Michael T. Ferdig, Boris Striepen, Karine G. Le Roch Apicomplexan parasites are responsible for numerous important human diseases including ...
The Escherichia coli Phosphotyrosine Proteome Relates to Core Pathways and Virulence
13-06-2013 | Anne-Marie Hansen et al., PLoS Pathogens, 2013
by Anne-Marie Hansen, Raghothama Chaerkady, Jyoti Sharma, J. Javier Díaz-Mejía, Nidhi Tyagi, Santosh Renuse, Harrys K. C. Jacob, Sneha M. Pinto, Nandini A. Sahasrabuddhe, Min-Sik Kim, Bernard Delanghe, Narayanaswamy Srinivasan, Andrew Emili, James B. Kaper, Akhilesh Pandey While ...
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