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609 Newest Publications in photochemistry and photobiology
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Roles of Porphyrin and Iron Metabolisms in the δ‐Aminolevulinic Acid (ALA)‐induced Accumulation of Protoporphyrin and Photodamage of Tumor Cells
01-09-2011 | Ohgari, Yoshiko; Miyata, Yoshinobu; Miyagi, Taeko; Gotoh, Saki; Ohta, Takano; Kataoka, Takao; Furuyama, Kazumichi; T ..., Photochemistry and Photobiology, 2011
Abstract δ‐Aminolevulinic acid (ALA)‐induced porphyrin accumulation is widely used in the treatment of cancer, as photodynamic therapy. To clarify the mechanisms of the tumor‐preferential accumulation of protoporphyrin, we examined the effect of the expression of heme‐biosynthetic and ...
Single Cell Responses to Spatially‐Controlled Photosensitized Production of Extracellular Singlet Oxygen
01-09-2011 | Pedersen, Brian W.; Sinks, Louise E.; Breitenbach, Thomas; Schack, Nickolass B.; Vinogradov, Sergei A.; Ogilby, Peter R., Photochemistry and Photobiology, 2011
Abstract The response of individual HeLa cells to extracellularly produced singlet oxygen was examined. The spatial domain of singlet oxygen production was controlled using the combination of a membrane‐impermeable Pd porphyrin‐dendrimer, which served as a photosensitizer, and a focused ...
Association of 25‐Hydroxyvitamin D3 Levels in Adult New Zealanders with Ethnicity, Skin Color and Self‐Reported Skin Sensitivity to Sun Exposure
01-09-2011 | Nessvi, Sofia; Johansson, Lisa; Jopson, Jan; Stewart, Alistair; Reeder, Anthony; McKenzie, Richard; Scragg, Robert K., Photochemistry and Photobiology, 2011
ABSTRACT The study aim was to determine the contribution of ethnicity, objectively measured skin color and skin reaction‐to‐sun exposure to variations in 25‐hydroxyvitamin D3 [25(OH)D3]. A multiethnic sample (European, Maori, Pacific and Asian) of 503 adult volunteers aged 18–85 years, ...
Calculation of Singlet Oxygen Dose Using Explicit and Implicit Dose Metrics During Benzoporphyrin Derivative Monoacid Ring A (BPD‐MA)‐PDT In Vitro and Correlation with MLL Cell Survival
01-09-2011 | Weston, Mark A.; Patterson, Michael S., Photochemistry and Photobiology, 2011
ABSTRACT Photodynamic therapy (PDT) oxygen consumption, clonogenic cell survival, fluorescence photobleaching and photoproduct formation were investigated during benzoporphyrin derivative monoacid (BPD‐MA)‐PDT of MAT‐LyLu cells in vitro. Cells were incubated with BPD‐MA concentrations of ...
γH2Ax: biomarker of damage or functional participant in DNA repair “All that glitters is not gold!”
29-08-2011 | James E Cleaver, Photochemistry and Photobiology, 2011
Abstract The phosphorylation of H2Ax on its S139 site, γH2Ax, is important for the assembly of repair complexes at DNA double strand breaks. The formation and functional role of γH2Ax after other kinds of DNA damage, especially UV light, where double strand breaks are rare, is less clear. ...
Photooxidation of Alkaloids: Considerable Quantum Yield Enhancement by Rose‐Bengal‐Sensitized Singlet Molecular Oxygen Generation
29-08-2011 | Görner, Helmut; Miskolczy, Zsombor; Megyesi, Mónika; Biczók, László, Photochemistry and Photobiology, 2011
ABSTRACT The photooxidation of sanguinarine, coralyne and berberine was studied in oxygenated alkaline methanol solutions. Rose bengal as photosensitizer significantly accelerates the process, indicating the importance of singlet molecular oxygen in the reaction mechanism. The quantum ...
Photosensitization Reactions In Vitro and In Vivo
29-08-2011 | Kruft, Bonnie I.; Greer, Alexander, Photochemistry and Photobiology, 2011
Abstract This review of Photochemistry and Photobiology summarizes articles published in 2010, and highlights progress in the area of photosensitization. The synthesis of conjugated photosensitizers is an area of interest where increasing water solubility has been a goal. Targeting ...
Cell‐type Selective Phototoxicity Achieved with Chlorophyll‐a Derived Photosensitizers in a Co‐culture System of Primary Human Tumor and Normal Lung Cells
29-08-2011 | Erin C. Tracy; Mary J. Bowman; Ravindra K. Pandey; Barbara W. Henderson; Heinz Baumann, Photochemistry and Photobiology, 2011
Abstract The ATP‐dependent transporter ABCG2 exports certain photosensitizers (PS) from cells, implying that the enhanced expression of ABCG2 by cancer cells may confer resistance to photodynamic therapy (PDT) mediated by those PS. In 35 patient‐derived primary cultures of lung epithelial ...
Effect of Laser Dose and Treatment Schedule on Excision Wound Healing in Diabetic Mice
29-08-2011 | Hegde, Vishal N.; Prabhu, Vijendra; Rao, Satish B.S.; Chandra, Subhash; Kumar, Pramod; Satyamoorthy, Kapaettu; Mahat ..., Photochemistry and Photobiology, 2011
ABSTRACT The present study was undertaken to evaluate a He‐Ne laser (632.8 nm; 7 mW; 4.02 mW/cm2; 15 mm spot size) dose and the treatment schedule on diabetic wound‐healing in a mouse model. Circular wounds of 15 mm diameter were created on streptozotocin induced diabetic Swiss albino ...
Alleviation of adverse effects of drought stress on growth and some potential physiological attributes in maize (Zea mays L.) by seed electromagnetic treatment
29-08-2011 | Namra Javed; Muhammad Ashraf; Nudrat Aisha Akram; Fahad Al‐Qurainy, Photochemistry and Photobiology, 2011
ABSTRACT Effects of varying pre‐seed magnetic treatments on growth, chlorophyll pigments, photosynthesis, water relation attributes, fluorescence and levels of osmoprotectants in maize plants were tested under normal and drought stress conditions. Seeds of two maize cultivars were treated ...
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