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147 Newest Publications in nutrition & metabolism

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Periodic 48h feed withdrawal improves glucose tolerance in growing pigs by enhancing adipogenesis and lipogenesis

09-02-2012 | Priya S Mir, Mao L He, Gregory Travis, Toby Entz, Tim Mcallister, Sigrid Marchand, Al Schaefer, Jon Meadus, Pierre L ..., Nutrition & Metabolism, 2012

Background: Adipocyte numbers and peroxisome proliferators activated receptorgamma (PPARgamma) expression of retroperitoneal tissue increased while area under the curve (AUC) during the glucose tolerance test (GTT) was reduced in rats subjected to certain feed withdrawal (FW) regimens. Thus, ...

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The chronic effects of fish oil with exercise on postprandial lipaemia and chylomicron homeostasis in insulin resistant viscerally obese men

07-02-2012 | Karin M Slivkoff-Clark, John CL Mamo, Anthony P James, Nutrition & Metabolism, 2012

Background: Visceral obesity and insulin resistance are associated with a postprandial accumulation of atherogenic chylomicron remnants that is difficult to modulate with lipid-lowering therapies. Dietary fish oil and exercise are cardioprotective interventions that can significantly modify ...

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Flaxseed dietary fibers lower cholesterol and increase fecal fat excretion, but magnitude of effect depend on food type

03-02-2012 | Mette Kristensen, Morten G Jensen, Julie Aarestrup, Kristina EN Petersen, Lise Sondergaard, Mette S Mikkelsen, Arne ..., Nutrition & Metabolism, 2012

Background: Dietary fibers have been proposed to play a role in cardiovascular risk as well as body weight management. Flaxseeds are a good source of dietary fibers, and a large proportion of these are water-soluble viscous fibers.MethodHere, we examine the effect of flaxseed dietary fibers ...

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Phenylketonuria: nutritional advances and challenges

03-02-2012 | Marcello Giovannini, Elvira Verduci, Elisabetta Salvatici, Sabrina Paci, Enrica Riva, Nutrition & Metabolism, 2012

Despite the appearance of new treatment, dietary approach remains the mainstay of PKU therapy. The nutritional management has become complex to optimize PKU patients' growth, development and diet compliance. This paper review critically new advances and challenges that have recently ...

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D-Lactate Altered Mitochondrial Energy Production in Rat Brain and Heart but not Liver

01-02-2012 | Binbing Ling, Fei Peng, Jane Alcorn, Katharina Lohmann, Brian Bandy, Gordon A Zello, Nutrition & Metabolism, 2012

Background: Substantially elevated blood D-lactate (DLA) concentrations are associated with neurocardiac toxicity in humans and animals. The neurological symptoms are similar to inherited or acquired abnormalities of pyruvate metabolism. We hypothesized that DLA interferes with mitochondrial ...

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Quality protein intake is inversely associated with abdominal fat

27-01-2012 | Jeremy P Loenneke, Jacob M Wilson, Anssi H Manninen, Mandy E Wray, Jeremy T Barnes, Thomas J Pujol, Nutrition & Metabolism, 2012

Dietary protein intake and specifically the quality of the protein in the diet has become an area of recent interest. This study determined the relationship between the amount of quality protein, carbohydrate, and dietary fat consumed and the amount of times the ~10g essential amino acid ...

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High prevalence of gastroesophageal reflux symptoms in type 2 diabetics with hypoadiponectinemia and metabolic syndrome

25-01-2012 | Ayumu Hirata, Ken Kishida, Hideaki Nakatsuji, Kana Inoue, Aki Hiuge-Shimizu, Tohru Funahashi, Iichiro Shimomura, Nutrition & Metabolism, 2012

Background: The prevalence of gastroesophageal reflux disease (GERD) has been increasing worldwide. Abdominal obesity or visceral fat accumulation rather than simple obesity is associated with GERD. Previous reports demonstrated the association between GERD and type 2 diabetes mellitus ...

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A high calcium diet containing nonfat dry milk reduces weight gain and associated adipose tissue inflammation in diet-induced obese mice when compared to high calcium alone

23-01-2012 | Anthony P. Thomas, Tamara N. Dunn, Josephine B. Drayton, Pieter J. Oort, Sean H. Adams, Nutrition & Metabolism, 2012

Background: High dietary calcium (Ca) is reported to have anti-obesity and anti-inflammatory properties. Evidence for these properties of dietary Ca in animal models of polygenic obesity have been confounded by the inclusion of dairy food components in experimental diets; thus, effect of Ca ...

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Population prevalence, attributable risk, and attributable risk percentage for high methylmalonic acid concentrations in the post-folic acid fortification period in the US

11-01-2012 | Vijay Ganji, Mohammad R Kafai, Nutrition & Metabolism, 2012

Background: Serum methylmalonic acid (MMA) is regarded as a sensitive marker of vitamin B-12 status. Elevated circulating MMA is linked to neurological abnormalities. Contribution of age, supplement use, kidney dysfunction, and vitamin B-12 deficiency to high serum MMA in post-folic acid ...

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Gamma-tocotrienol does not substantially protect DS neurons from hydrogen peroxide-induced oxidative injury

05-01-2012 | Sue-Mian Then, Coral Sanfeliu, Gapor M Top, Wan Zurinah Wan Ngah, Musalmah Mazlan, Nutrition & Metabolism, 2012

Background: Down syndrome (DS) neurons are more susceptible to oxidative stress and previous studies have shown that vitamin E was able to reduce oxidative stress and improve DS neurons' viability. Therefore, this study was done to investigate the protective role of gamma-tocotrienol (gT3) ...

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