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7,935 Newest Publications in nucleic acids research

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fusionDB: assessing microbial diversity and environmental preferences via functional similarity networks

29-Nov-2017 | Zhu C, Mahlich Y, Miller M, et al., Nucleic Acids Research, 2017

Nucleic Acids Research (2017), https://doi.org/10.1093/nar/gkx1060

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The international nucleotide sequence database collaboration

28-Nov-2017 | Karsch-Mizrachi I, Takagi T, Cochrane G, et al., Nucleic Acids Research, 2017

Abstract For more than 30 years, the International Nucleotide Sequence Database Collaboration (INSDC; http://www.insdc.org/) has been committed to capturing, preserving and providing access to comprehensive public domain nucleotide sequence and associated metadata which enables discovery in ...

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The European Bioinformatics Institute in 2017: data coordination and integration

25-Nov-2017 | Cook C, Bergman M, Cochrane G, et al., Nucleic Acids Research, 2017

Abstract The European Bioinformatics Institute (EMBL-EBI) supports life-science research throughout the world by providing open data, open-source software and analytical tools, and technical infrastructure (https://www.ebi.ac.uk). We accommodate an increasingly diverse range of data types and ...

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FunCoup 4: new species, data, and visualization

20-Nov-2017 | Ogris C, Guala D, M, et al., Nucleic Acids Research, 2017

Abstract This release of the FunCoup database (http://funcoup.sbc.su.se) is the fourth generation of one of the most comprehensive databases for genome-wide functional association networks. These functional associations are inferred via integrating various data types using a naive Bayesian ...

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MethBank 3.0: a database of DNA methylomes across a variety of species

17-Nov-2017 | Li R, Liang F, Li M, et al., Nucleic Acids Research, 2017

Abstract MethBank (http://bigd.big.ac.cn/methbank) is a database that integrates high-quality DNA methylomes across a variety of species and provides an interactive browser for visualization of methylation data. Here, we present an updated implementation of MethBank (version 3.0) by incorporating ...

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JASPAR 2018: update of the open-access database of transcription factor binding profiles and its web framework

17-Nov-2017 | Khan A, Fornes O, Stigliani A, et al., Nucleic Acids Research, 2017

Nucleic Acids Research (2017), https://doi.org/10.1093/nar/gkx1126

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Ensembl 2018

16-Nov-2017 | Zerbino D, Achuthan P, Akanni W, et al., Nucleic Acids Research, 2017

Abstract The Ensembl project has been aggregating, processing, integrating and redistributing genomic datasets since the initial releases of the draft human genome, with the aim of accelerating genomics research through rapid open distribution of public data. Large amounts of raw data are thus ...

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aBiofilm: a resource of anti-biofilm agents and their potential implications in targeting antibiotic drug resistance

16-Nov-2017 | Rajput A, Thakur A, Sharma S, et al., Nucleic Acids Research, 2017

Abstract Biofilms play an important role in the antibiotic drug resistance, which is threatening public health globally. Almost, all microbes mimic multicellular lifestyle to form biofilm by undergoing phenotypic changes to adapt adverse environmental conditions. Many anti-biofilm agents have ...

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GPCRdb in 2018: adding GPCR structure models and ligands

16-Nov-2017 | Pándy-Szekeres G, Munk C, Tsonkov T, et al., Nucleic Acids Research, 2017

Abstract G protein-coupled receptors are the most abundant mediators of both human signalling processes and therapeutic effects. Herein, we report GPCRome-wide homology models of unprecedented quality, and roughly 150 000 GPCR ligands with data on biological activities and commercial ...

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PRGdb 3.0: a comprehensive platform for prediction and analysis of plant disease resistance genes

16-Nov-2017 | Osuna-Cruz C, Paytuvi-Gallart A, Di Donato A, et al., Nucleic Acids Research, 2017

Abstract The Plant Resistance Genes database (PRGdb; http://prgdb.org) has been redesigned with a new user interface, new sections, new tools and new data for genetic improvement, allowing easy access not only to the plant science research community but also to breeders who want to improve plant ...

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