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510 Newest Publications in cell and tissue research

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Bone-marrow-derived cells cultured in serum-free medium reduce liver fibrosis and improve liver function in carbon-tetrachloride-treated cirrhotic mice

27-11-2012 | Takuya Iwamoto, Shuji Terai, Takuro Hisanaga, Taro Takami, Naoki Yamamoto, Shoko Watanabe, Isao Sakaida, Cell and Tissue Research, 2012

We have previously developed autologous bone marrow cell infusion (ABMi) therapy for liver cirrhosis patients. One problem associated with ABMi therapy is that general anesthesia is required to obtain 400 ml bone marrow fluid from liver cirrhosis patients. However, many patients with ...

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Double-stranded RNA-dependent protein kinase regulates insulin-stimulated chondrogenesis in mouse clonal chondrogenic cells, ATDC-5

26-11-2012 | Hiroyuki Morimoto, Ryoko Baba, Tatsuji Haneji, Yoshiaki Doi, Cell and Tissue Research, 2012

Double-stranded RNA-dependent protein kinase (PKR) is an interferon-induced protein that has been identified and characterized as a translational inhibitor in an interferon-regulated antiviral pathway. PKR is also reported to play important roles in the regulation of cell growth and ...

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Subcellular localization of the epitheliopeptide, Hym-301, in hydra

26-11-2012 | Yasuharu Takaku, Hiroshi Shimizu, Toshio Takahashi, Toshitaka Fujisawa, Cell and Tissue Research, 2012

Peptides, as signaling molecules, play a number of roles in cell activities. An epitheliopeptide, Hym-301, has been described as a peptide involved in morphogenesis in hydra. However, little is known about the intracellular location of the peptide or its specific functions. To investigate the ...

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Effects of dietary fish oil and corn oil on rat mammary tissue

26-11-2012 | Serge Delpal, Alain Pauloin, Catherine Hue-Beauvais, Valérie Berthelot, Philippe Schmidely, Michèle Ollivier-Bousquet, Cell and Tissue Research, 2012

The effects, on the maternal mammary gland, of diets containing similar lipid percentages but differing in composition of polyunsaturated fatty acids (PUFA) have been assessed in rats during pregnancy and lactation. For this purpose, tuna fish oil (an n-3-PUFA-enriched oil) and corn oil (an ...

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Activation of autophagic programmed cell death and innate immune gene expression reveals immuno-competence of integumental epithelium in Bombyx mori infected by a dipteran parasitoid

19-11-2012 | Appukuttan Nair R. Pradeep, Jayaram Anitha, Arvind K. Awasthi, Mohd. A. Babu, Murthy N. Geetha, Hariharan K. Arun, S ..., Cell and Tissue Research, 2012

In insects, the integument forms the primary barrier between the environment and internal milieu, but cellular and immune responses of the integumental epithelium to infection by micro- and macro-parasites are mostly unknown. We elucidated cellular and immune responses of the epithelium ...

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Orexin-B-like immunoreactivity localizes in both luteinizing-hormone-containing cells and melanin-concentrating hormone-containing fibers in the red-bellied piranha (Pygocentrus nattereri) pituitary

19-11-2012 | Hirohumi Suzuki, Toshiharu Yamamoto, Cell and Tissue Research, 2012

We examined orexin-like immunoreactivity in the pituitary of the red-bellied piranha (Pygocentrus nattereri). Orexin-B-immunoreactive (IR) cells corresponded to luteinizing hormone (LH)-containing cells in the pars distalis, and orexin-B-IR fibers corresponded to melanin-concentrating hormone ...

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The molecular basis of induction and formation of tunneling nanotubes

15-11-2012 | Shunsuke Kimura, Koji Hase, Hiroshi Ohno, Cell and Tissue Research, 2012

Tunneling nanotubes (TNTs) and associated structures are recently recognized structures for intercellular communication. They are F-actin-containing thin protrusions of the plasma membrane of a cell and allow a direct physical connection to the plasma membranes of remote cells. TNTs and ...

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Antimicrobial properties of Anopheles albimanus pericardial cells

15-11-2012 | Salvador Hernández-Martínez, Humberto Lanz-Mendoza, Jesús Martínez-Barnetche, Mario H. Rodríguez, Cell and Tissue Research, 2012

Insect pericardial cells (PCs) are strategically located along the dorsal vessel where they encounter a high hemolymph flow enabling them to undertake their osmoregulatory, detoxifying, and scavenging functions. In this location, PCs also encounter foreign molecules and microorganisms. The ...

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Lentiviral-mediated over-expression of hyaluronan synthase-1 (HAS-1) decreases the cellular inflammatory response and results in regenerative wound repair

13-11-2012 | Robert C. Caskey, Myron Allukian, Robert C. Lind, Benjamin J. Herdrich, Junwang Xu, Antoneta Radu, Marc E. Mitchell, ..., Cell and Tissue Research, 2012

Fetal wounds have been found to have increased levels of high-molecular-weight hyaluronan (HMW-HA) compared with those of adults. The primary enzyme responsible for producing HMW-HA is hyaluronic acid synthase-1 (HAS-1). We hypothesized that over-expression of HAS-1 in adult dermal wounds ...

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Gene expression changes in the secondary palate and mandible of Prdm16−/− mice

13-11-2012 | Dennis R. Warner, Justin P. Wells, Robert M. Greene, M. Michele Pisano, Cell and Tissue Research, 2012

Loss of Prdm16 expression in the mouse leads to a complete cleft of the secondary palate. We have now determined changes in gene expression in the secondary palates of Prdm16 −/− fetuses in an attempt to reveal the mechanism(s) leading to the failure of palate closure in these mice. Defined ...

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