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579 Newest Publications in annals of biomedical engineering
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Irreversible Electroporation: An In Vivo Study with Dorsal Skin Fold Chamber
25-11-2012 | Zhenpeng Qin, Jing Jiang, Gary Long, Bruce Lindgren, John C. Bischof, Annals of Biomedical Engineering, 2012
Irreversible electroporation (IRE) has been proposed to destroy large amounts of tumorous tissue and shows advantages over thermal therapies. Unfortunately, carefully constructed studies assessing impact in in vivo tumor systems and a direct comparison of IRE with thermal therapy are lacking. ...
Transtibial Amputee Joint Motion has Increased Attractor Divergence During Walking Compared to Non-Amputee Gait
25-11-2012 | Shane R. Wurdeman, Sara A. Myers, Nicholas Stergiou, Annals of Biomedical Engineering, 2012
The amputation and subsequent prosthetic rehabilitation of a lower leg affects gait. Dynamical systems theory would predict the use of a prosthetic device should alter the functional attractor dynamics to which the system self-organizes. Therefore, the purpose of this study was to compare the ...
Endothelial Dysfunction, Arterial Stiffening, and Intima-Media Thickening in Large Arteries from HIV-1 Transgenic Mice
25-11-2012 | Laura Hansen, Ivana Parker, Roy L. Sutliff, Manu O. Platt, Rudolph L. Gleason Jr., Annals of Biomedical Engineering, 2012
HIV patients on highly active antiretroviral therapy (HAART) exhibit elevated incidence of cardiovascular disease (CVD), including a higher risk of myocardial infarction and prevalence of atherosclerotic lesions, as well as increases in markers of subclinical atherosclerosis including ...
A Finite Element Model of the Lower Limb for Simulating Automotive Impacts
25-11-2012 | Costin D. Untaroiu, Neng Yue, Jaeho Shin, Annals of Biomedical Engineering, 2012
A finite element (FE) model of a vehicle occupant’s lower limb was developed in this study to improve understanding of injury mechanisms during traffic crashes. The reconstructed geometry of a male volunteer close to the anthropometry of a 50th percentile male was meshed using mostly ...
Error Mechanisms of the Oscillometric Fixed-Ratio Blood Pressure Measurement Method
25-11-2012 | Jiankun Liu, Jin-Oh Hahn, Ramakrishna Mukkamala, Annals of Biomedical Engineering, 2012
The oscillometric fixed-ratio method is widely employed for non-invasive measurement of systolic and diastolic pressures (SP and DP) but is heuristic and prone to error. We investigated the accuracy of this method using an established mathematical model of oscillometry. First, to determine ...
Surface Curvature as a Classifier of Abdominal Aortic Aneurysms: A Comparative Analysis
25-11-2012 | Kibaek Lee, Junjun Zhu, Judy Shum, Yongjie Zhang, Satish C. Muluk, Ankur Chandra, Mark K. Eskandari, Ender A. Finol, Annals of Biomedical Engineering, 2012
An abdominal aortic aneurysm (AAA) carries one of the highest mortality rates among vascular diseases when it ruptures. To predict the role of surface curvature in rupture risk assessment, a discriminatory analysis of aneurysm geometry characterization was conducted. Data was obtained from ...
A Computational Approach to Understand Phenotypic Structure and Constitutive Mechanics Relationships of Single Cells
25-11-2012 | Scott T. Wood, Brian C. Dean, Delphine Dean, Annals of Biomedical Engineering, 2012
The goal of this study is to construct a representative 3D finite element model (FEM) of individual cells based on their sub-cellular structures that predicts cell mechanical behavior. The FEM simulations replicate atomic force microscopy (AFM) nanoindentation experiments on live vascular ...
Characterizing the Collagen Fiber Orientation in Pericardial Leaflets Under Mechanical Loading Conditions
25-11-2012 | S. Hamed Alavi, Victor Ruiz, Tatiana Krasieva, Elliot L. Botvinick, Arash Kheradvar, Annals of Biomedical Engineering, 2012
When implanted inside the body, bioprosthetic heart valve leaflets experience a variety of cyclic mechanical stresses such as shear stress due to blood flow when the valve is open, flexural stress due to cyclic opening and closure of the valve, and tensile stress when the valve is closed. ...
Accelerometry Reveals Differences in Gait Variability Between Patients with Multiple Sclerosis and Healthy Controls
19-11-2012 | Jessie M. Huisinga, Martina Mancini, Rebecca J. St. George, Fay B. Horak, Annals of Biomedical Engineering, 2012
Variability of movement reflects important information for the maintenance of the health of the system. For pathological populations, changes in variability during gait signal the presence of abnormal motor control strategies. For persons with multiple sclerosis (PwMS), extensive gait ...
Linking the Development of Ventilator-Induced Injury to Mechanical Function in the Lung
19-11-2012 | Bradford J. Smith, Kara A. Grant, Jason H. T. Bates, Annals of Biomedical Engineering, 2012
Management of ALI/ARDS involves supportive ventilation at low tidal volumes (V t) to minimize the rate at which ventilator induced lung injury (VILI) develops while the lungs heal. However, we currently have few details to guide the minimization of VILI in the ALI/ARDS patient. The goal of ...
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