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15,586 Newest Publications from the industry pharma
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Flurbiprofen benzyl nitrate (NBS-242) inhibits the growth of A-431 human epidermoid carcinoma cells and targets ß-catenin
15-05-2013 | Nath N, Liu X, Jacobs L, Kashfi K, Drug Design, Development and Therapy, 2013
Nath N, Liu X, Jacobs L, Kashfi K
Overcoming therapeutic obstacles in inflammatory bowel diseases; A comprehensive review on novel drug delivery strategies
12-05-2013 | Author(s): F. Talaie , F. Atyabi , M. Azjdarzadeh , R. Dinarvand , A. Saadatzadeh, European Journal of Pharmaceutical Science, 2013
Publication date: Available online 9 May 2013 Source:European Journal of Pharmaceutical Sciences Author(s): F. Talaie , F. Atyabi , M. Azjdarzadeh , R. Dinarvand , A. Saadatzadeh Inflammatory bowel diseases (IBD) are a group of debilitating inflammatory complications specially ...
Statins modulate feedback regulation mechanisms between advanced glycation end-products and C-reactive protein: evidence in patients with acute myocardial infarction
12-05-2013 | Author(s): Beatriz Paradela-Dobarro , Sergio Raposeiras-Roubín , Bruno K. Rodiño-Janeiro , Lilian Grigorian-Sham ..., European Journal of Pharmaceutical Science, 2013
Publication date: Available online 9 May 2013 Source:European Journal of Pharmaceutical Sciences Author(s): Beatriz Paradela-Dobarro , Sergio Raposeiras-Roubín , Bruno K. Rodiño-Janeiro , Lilian Grigorian-Shamagian , José M. García-Acuña , Pablo Aguiar-Souto , Michel ...
A Novel Manganese Complex, Mn-(II) N-(2-Hydroxy Acetophenone) Glycinate overcomes Multidrug-Resistance in Cancer
12-05-2013 | Author(s): Ruma Dey Ghosh , Kaushik Banerjee , Satyajit Das , Avishek Ganguly , Paramita Chakraborty , Avijit ..., European Journal of Pharmaceutical Science, 2013
Publication date: Available online 9 May 2013 Source:European Journal of Pharmaceutical Sciences Author(s): Ruma Dey Ghosh , Kaushik Banerjee , Satyajit Das , Avishek Ganguly , Paramita Chakraborty , Avijit Sarkar , Mitali Chatterjee , Soumitra K Choudhuri Multidrug resistance ...
Equilibrium and release properties of hyaluronic acid–drug complexes
12-05-2013 | Author(s): Battistini Franco David , Olivera María Eugenia , Manzo Rubén Hilario, European Journal of Pharmaceutical Science, 2013
Publication date: Available online 6 May 2013 Source:European Journal of Pharmaceutical Sciences Author(s): Battistini Franco David , Olivera María Eugenia , Manzo Rubén Hilario With the aim to provide more rational basis about the potentiality of hyaluronic acid (or hyaluronan) as ...
The Impact of Noncardiovascular Surgery on Reactive Hyperaemia and Arterial Endothelial Function
11-05-2013 | Yan Jun Hu, An Ning Wei, Ping Chook, Yuehui Yin, William Cheng, Meng Jun Wu, David S Celermajer, Kam Sang Woo, Clinical and Experimental Pharmacology and Physiology, 2013
Summary Vascular reactivity is a surrogate marker for atherosclerosis and is predictive of cardiovascular outcome. Noncardiovascular surgery is associated with perioperative cardiovascular complications in high risk patients. To evaluate the impact of noncardiovascular surgery on ...
Temporal development of baroreceptor dysfunction in a rodent model of chronic kidney disease
11-05-2013 | Cara M. Hildreth, Divya Sarma Kandukuri, Ann K. Goodchild, Jacqueline K. Phillips, Clinical and Experimental Pharmacology and Physiology, 2013
Summary autonomic control of the cardiovascular system in chronic kidney disease (CKD) contributes to an increased risk of cardiovascular events. We aimed to determine if and when autonomic dysfunction occurs in a conscious, telemetered, rodent model of CKD. In Lewis Polycystic ...
Endothelin receptors in augmented vasoconstrictor responses to endothelin‐1 in chronic intermittent hypoxia
11-05-2013 | Qiu‐Hong Guo, Yi‐Long Tian, Zhuo Wan, Ai‐Ying Li, Zhi‐Hong Ma, Ya‐Jing Guo, J. Woodrow Weiss, En‐Sheng Ji, Li Chu, Clinical and Experimental Pharmacology and Physiology, 2013
Summary Chronic intermittent hypoxia (CIH) contributes to the development of cardiovascular diseases in patients with obstructive sleep apnoea. Many studies have shown an association between increased circulating endothelin (ET)‐1 levels and CIH. The aim of the present study was to ...
Extra‐renal Roles of the WNKs
11-05-2013 | Keith Siew, Kevin M. O'Shaughnessy, Clinical and Experimental Pharmacology and Physiology, 2013
Summary Identified over a decade ago, the With‐No‐Lysine[K] (WNK)s have been the subsequent focus of intense research into the renal handling of Na+, Cl‐, K+ and several rare monogenetic diseases. However the potential extra‐renal roles for WNKs have been less well explored. Thiazides ...
A toxicity risk index, an index for warning idiosyncratic drug toxicity
10-05-2013 | Miyoshi Morimoto, Kazuo Samizo, Shin Ohta, Takashi Mizuma, Journal of Pharmaceutical Sciences, 2013
Abstract Drug toxicity impedes drug development and its clinical use. In the present study, a toxicity risk index (TRI), which is an index for warning idiosyncratic drug toxicity (IDT), was proposed. The TRI of drugs was defined as a function of dose, pharmacokinetic parameters, and ...
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