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806 Newest Publications from the industry diagnostics
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Global gene expression analysis of amniotic fluid cell‐free RNA from recipient twins with twin‐twin transfusion syndrome
02-05-2013 | Lisa Hui, Heather C. Wick, Kenneth J. Moise, Anthony Johnson, Francois Luks, Sina Haeri, Kirby L. Johnson, Diana W. ..., Prenatal Diagnosis, 2013
ABSTRACT Objective To understand the biological pathways involved in twin‐twin transfusion syndrome (TTTS) by performing global gene expression analysis of amniotic fluid (AF) cell‐free RNA. Methods Prospective whole transcriptome microarray study analyzing cell‐free RNA in AF ...
Prenatal control of nondeletional α‐thalassemia: first experience in mainland China
02-05-2013 | Jian Li, Ru Li, Jian‐Ying Zhou, Xing‐Mei Xie, Can Liao, Dong‐Zhi Li, Prenatal Diagnosis, 2013
ABSTRACT Objective To demonstrate the performance of nondeletional α‐thalassemia prevention at a mainland Chinese hospital. Methods A prenatal control program for nondeletional hemoglobin H (Hb H) disease was conducted from January 2010 to June 2012. All couples were screened for ...
The fetal frontomaxillary facial angle in normal and trisomy 21 ultrasounds at 11–13+6 weeks of gestation: findings among the ethnic Chinese compared with Caucasian
02-05-2013 | Ching Hua Hsiao, Wen Liang Liu, Ran Chou Chen, Bo Jen Cheng, Yin Jiun Tseng, Woei Chyn Chu, Prenatal Diagnosis, 2013
ABSTRACT Objective The aim of this research was to compare the fetal frontomaxillary facial (FMF) angle between normal and trisomy 21 fetuses at 11+0–13+6 weeks gestation in a Chinese population. Methods A prospective observational study was performed that included 640 euploid ...
Diagnostics for tuberculosis: what test developers want to know
02-05-2013 | Madhukar Pai, Expert Review of Molecular Diagnostics, 2013
Expert Review of Molecular Diagnostics , May 2013, Vol. 13, No. 4, Pages 311-314.
Quantum dot-based nanosensors for diagnosis via enzyme activity measurement
02-05-2013 | Birgitta R Knudsen; Morten Leth Jepsen; Yi-Ping Ho, Expert Review of Molecular Diagnostics, 2013
Enzymes are essential in the human body, and the disorder of enzymatic activities has been associated with many different diseases and stages of disease. Luminescent semiconductor nanocrystals, also known as quantum dots (QDs), have garnered great attention in molecular diagnostics. Owing to ...
Single molecular weight discrete PEG compounds: emerging roles in molecular diagnostics, imaging and therapeutics
02-05-2013 | Stephen P Povoski; Paul D Davis; David Colcher; Edward W Martin Jr, Expert Review of Molecular Diagnostics, 2013
Expert Review of Molecular Diagnostics , May 2013, Vol. 13, No. 4, Pages 315-319.
Genetic background of idiopathic pulmonary fibrosis
02-05-2013 | Simona Santangelo; Simone Scarlata; Anna Zito; Domenica Chiurco; Claudio Pedone; Raffaele Antonelli Incalzi, Expert Review of Molecular Diagnostics, 2013
Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive lung disease characterized by progressive fibrosing interstitial pneumonia. The histological pattern, which displays dense fibrosis with active areas of fibroblastic proliferation, suggests a pathogenetic role of aberrant response ...
Metabolomics for tumor marker discovery and identification based on chromatography–mass spectrometry
02-05-2013 | Peiyuan Yin; Guowang Xu, Expert Review of Molecular Diagnostics, 2013
Early detection is the most effective way to improve the clinical outcome of malignancies. Although some tumor markers are now widely used in the clinic, their sensitivity and specificity are still not satisfactory. Thus, there is an urgent requirement for the discovery of new tumor markers. ...
Impact of metabolizing enzymes on drug response of endocrine therapy in breast cancer
02-05-2013 | Pilar H Saladores; Jana C Precht; Werner Schroth; Hiltrud Brauch; Matthias Schwab, Expert Review of Molecular Diagnostics, 2013
Estrogen-receptor positive breast cancer accounts for 75% of diagnosed breast cancers worldwide. There are currently two major options for adjuvant treatment: tamoxifen and aromatase inhibitors. Variability in metabolizing enzymes determines their pharmacokinetic profile, possibly affecting ...
Application of mass spectrometry to molecular diagnostics of viral infections
02-05-2013 | Lilia M Ganova-Raeva; Yury E Khudyakov, Expert Review of Molecular Diagnostics, 2013
Mass spectrometry (MS) has found numerous applications in life sciences. It has high accuracy, sensitivity and wide dynamic range in addition to medium- to high-throughput capabilities. These features make MS a superior platform for analysis of various biomolecules including proteins, lipids, ...
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