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26 Newest Publications
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Effects of unconjugated bilirubin on chromosomal damage in individuals with Gilbert`s syndrome measured with the micronucleus cytome assay
01-11-2012 | M. Wallner; S. M. Blassnigg; K. Marisch; M. T. Pappenheim; E. Müllner; C. Mölzer; A. Nersesyan; R. Marculescu; D. Do ..., Mutagenesis, 2012
Circulating unconjugated bilirubin (UCB) has been reported to protect against lung and colorectal cancer. The present study aimed to explore, for the first time, whether mildly elevated...
Mesenchymal stem cells promote a primitive phenotype CD34+c-kit+ in human cord blood-derived hematopoietic stem cells during ex vivo expansion
28-10-2012 | Viviana M. Rodríguez-Pardo, Jean Paul Vernot, Cellular & Molecular Biology Letters, 2012
(including the c-kit+ marker) and clonogenic capacity of hematopoietic stem cells (HSC). BM-MSC were collected from volunteer donors, isolated and characterized. Umbilical cord blood (UCB) samples were...
Unconjugated Bilirubin Restricts Oligodendrocyte Differentiation and Axonal Myelination
20-10-2012 | Andreia Barateiro, Veronique E. Miron, Sofia D. Santos, João B. Relvas, Adelaide Fernandes, Charles ffrench-Constant ..., Molecular Neurobiology, 2012
High levels of serum unconjugated bilirubin (UCB) in newborns are associated with axonal damage and glial reactivity that may contribute to subsequent neurologic injury and encephalopathy...
Evaluation of FMH QuikQuant for the detection and quantification of fetomaternal hemorrhage
01-10-2012 | Cedric Pastoret, Jerome Le Priol, Thierry Fest, Mikael Roussel, Cytometry Part B: Clinical Cytometry, 2012
to evaluate the performance of a flow cytometry (FCM) kit (FMH QuikQuant) using an anti‐HbF antibody. Methods: 83 pregnant women, 58 umbilical cord blood (UCB) dilutions in adult blood and 6 control...
Adipose Stem Cell-derived Osteoblasts sustain the functionality of Endothelial progenitors from the mononuclear fraction of Umbilical Cord Blood
24-09-2012 | R.P. Pirraco, B. Ferreira, T.C. Santos, A.M. Frias, A.P. Marques, R.L. Reis, Acta Biomaterialia, 2012
’s survival. The combination of endothelial cells with current TE strategies seems the most promising approach but doubts persist on which type of endothelial cells to use. Umbilical cord blood (UCB) cells have...
The autoimmunity-associated BLK haplotype exhibits cis-regulatory effects on mRNA and protein expression that are prominently observed in B cells early in development
01-09-2012 | Kim R. Simpfendorfer; Lina M. Olsson; Nataly Manjarrez Orduño; Houman Khalili; Alyssa M. Simeone; Matthew S. Katz; A ..., Human Molecular Genetics, 2012
in later stages of differentiation. Allelic expression bias was also identified in primary human T cells from adult peripheral and umbilical cord blood (UCB), thymus and tonsil, although mRNA levels were...
Pilot Social Feasibility Study for the Establishment of a Public Human Umbilical Cord Blood Stem Cell Bank in South Africa
22-06-2012 | Madelein Meissner-Roloff, Wendy Young, Isabella Rangaka, Hennie Lombaard, Ames Dhai, Norma Tsotsi, Michael S. Pepper, Stem Cell Reviews, 2012
There is a large unmet need in South Africa for bone marrow transplantation. Umbilical cord blood (UCB) is an important source of stem cells for the treatment of haematological and non...
The use of sodium oxybate to treat narcolepsy
02-05-2012 | Geert Mayer, Expert Review of Neurotherapeutics, 2012
, was restricted to stimulants, whereas the second core symptom, cataplexy, was treated with antidepressants, and the resultant fragmented night-time sleep with hypnotics. Sodium oxybate (Xyrem®, UCB Pharma...
Urothelial tumor initiation requires deregulation of multiple signaling pathways: implications in target-based therapies
01-04-2012 | Zhou, Haiping; Huang, Hong-ying; Shapiro, Ellen; Lepor, Herbert; Huang, William C.; Mohammadi, Moosa; Mohr, Ian; Tan ..., Carcinogenesis , 2012
Although formation of urothelial carcinoma of the bladder (UCB) requires multiple steps and proceeds along divergent pathways, the underlying genetic and molecular determinants for each step...
Mesenchymal stem cells from umbilical cord blood: parameters for isolation, characterization and adipogenic differentiation
11-02-2012 | Tatiana Taís Sibov, P. Severino, L. C. Marti, L. F. Pavon, D. M. Oliveira, P. R. Tobo, A. H. Campos, A. T. Paes, E. ..., Cytotechnology, 2012
Isolation of mesenchymal stem cells (MSCs) from umbilical cord blood (UCB) from full-term deliveries is a laborious, time-consuming process that results in a low yield of cells. In this study we...
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