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Le cancer de la prostate est une maladie grandement affectée par le style de vie, particulièrement la diète, et il est plus fréquent aux États-Unis et dans les pays européens comparativement à l'Asie de sud et de l'est. Parmi les nombreuses causes et facteurs de risques connus, la nutrition ... more
BJD Editor's Choice Journal of Investigative Dermatology 133, 1700 (July 2013). doi:10.1038/jid.2013.210 more
Report on the 6th International Conference of HPV, Polyomavirus, and UV Radiation in Skin Cancer Journal of Investigative Dermatology 133, 1702 (July 2013). doi:10.1038/jid.2013.51 Authors: Ingo Nindl, Eggert Stockfleth & Thomas G Hofmann more
Editors' Picks Journal of Investigative Dermatology 133, 1701 (July 2013). doi:10.1038/jid.2013.211 more
As I Said Before... Journal of Investigative Dermatology 133, 1697 (July 2013). doi:10.1038/jid.2012.342 Authors: Barbara A Gilchrest & Elizabeth N Blalock more
Otitis media with effusion (OME) is the most common cause of hearing loss in children and tympanostomy to alleviate the condition remains the commonest surgical intervention in children in the developed world. Chronic and recurrent forms of OM are known to have a very significant genetic c ... more
Small intestinal epithelial cells (sIECs) have a significant share in whole body metabolism as they perform enzymatic digestion and absorption of nutrients. Furthermore, the diet plays a key role in a number of complex diseases including obesity and diabetes. The impact of diet and altered ... more
Visual refractive errors (REs) are complex genetic traits with a largely unknown etiology. To date, genome-wide association studies (GWASs) of moderate size have identified several novel risk markers for RE, measured here as mean spherical equivalent (MSE). We performed a GWAS using a tota ... more
Large intronic expansions of the triplet-repeat sequence (GAA.TTC) cause transcriptional repression of the Frataxin gene (FXN) leading to Friedreich's ataxia (FRDA). We previously found that GAA-triplet expansions stimulate heterochromatinization in vivo in transgenic mice. We report here ... more
Mutations in Parkin or PINK1 are the most common cause of recessively inherited parkinsonism. Parkin and PINK1 function in a conserved mitochondrial quality control pathway, in which PINK1, a putative mitochondrial kinase, directs Parkin, a cytosolic E3 ubiquitin ligase, selectively to dys ... more
The megalencephaly‐capillary malformation (MCAP) syndrome is a rare disorder characterized by prenatal overgrowth, somatic and cerebral asymmetry, cutaneous vascular malformations, and connective tissues abnormalities.1 The central nervous system (CNS) and cutaneous manifestations dominat ... more
ABSTRACT Recently, a new subgroup of Gaucher's disease type 2 with early manifestations during fetal life has been reported. This report illustrates the diversity of fetal malformations observed in this entity, also called perinatal lethal Gaucher's disease, and, because of phenotypic v ... more
ABSTRACT Objectives To evaluate whether a relationship exists between season at conception and occurrence of Isolated Spina Bifida (ISB). Study design All fetuses with prenatal diagnosis of ISB were analyzed according to date of conception. We compared the seasonal rates of con ... more
ABSTRACT Objective This study aims to evaluate the utility of first trimester cervical ultrasonography in predicting preterm delivery by separate analysis of measurements of cervical and isthmus length. Methods This is a cohort study based on data collected prospectively on sin ... more
ABSTRACT Objective To compare the angio‐architecture of monochorionic placentas of spontaneous twin anaemia‐polycythemia sequence (TAPS) with placenta of Twin to Twin Transfusion Syndrome (TTTS) with residual anastomoses after laser coagulation and placentas of uncomplicated monochori ... more
Inside Lab Invest Laboratory Investigation 93, 624 (June 2013). doi:10.1038/labinvest.2013.68 more
Inside Lab Invest Laboratory Investigation 93, 500 (May 2013). doi:10.1038/labinvest.2013.58 more
Inside Lab Invest Laboratory Investigation 93, 376 (April 2013). doi:10.1038/labinvest.2013.49 more
Methods for defining distinct bioenergetic profiles in platelets, lymphocytes, monocytes, and neutrophils, and the oxidative burst from human blood Laboratory Investigation advance online publication, March 25 2013. doi:10.1038/labinvest.2013.53 Authors: Balu K Chacko, Phili ... more
Inside Lab Invest Laboratory Investigation 93, 266 (March 2013). doi:10.1038/labinvest.2013.11 more
Abstract: Endometrial cancer is a highly curable malignancy when it presents as uterine-confined disease, but the prognosis for metastatic or recurrent endometrial cancer is poor. For those patients which are diagnosed at an early stage, surgery alone may be adequate for cure and c ... more
Abstract: Metastasis is the major cause of death in breast cancer patients. In this study, we investigated the effects of baicalin, a natural compound, on cell migration, invasion and metastasis using human breast cancer MDA-MB-231 cell line as model system. Baicalin not only dose- ... more
Abstract: Objective: To investigate the effect of cucurmosin (CUS) on proliferation inhibition in the human pancreatic cancer cell line SW-1990 in vitro and in vivo. Methods: 1. MTT assay was used to analyse the proliferation inhibition of CUS in SW-1990 cells compared with gemc ... more
Abstract: The structural changes in DNA caused by the combined effects of TiO2 nanoparticles (TiO2 NPs) and doxorubicin (DOX) were investigated along with their corresponding inhibitory roles in the growth of T47D and MCF7 cells. The UV-visible titration studies showed that DOX+ Ti ... more
Abstract: Treatment of locally advanced non-small cell lung cancer (NSCLC) remains a significant challenge for oncologists, despite progress made in recent years in early diagnosis and therapy. This review focuses on integrated therapeutic approaches of patients with locally advanc ... more
BJD Editor's Choice Journal of Investigative Dermatology 133, 1700 (July 2013). doi:10.1038/jid.2013.210 more
Report on the 6th International Conference of HPV, Polyomavirus, and UV Radiation in Skin Cancer Journal of Investigative Dermatology 133, 1702 (July 2013). doi:10.1038/jid.2013.51 Authors: Ingo Nindl, Eggert Stockfleth & Thomas G Hofmann more
Editors' Picks Journal of Investigative Dermatology 133, 1701 (July 2013). doi:10.1038/jid.2013.211 more
As I Said Before... Journal of Investigative Dermatology 133, 1697 (July 2013). doi:10.1038/jid.2012.342 Authors: Barbara A Gilchrest & Elizabeth N Blalock more
North, South, or East? Blotting Techniques Journal of Investigative Dermatology 133, e10 (July 2013). doi:10.1038/jid.2013.216 Authors: M W Nicholas & Kelly Nelson more
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