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Publications

Search for science publications by its title or author and refine your search on the basis of publishing houses, year etc.

Current publications

A novel BCMA|[sol]|CD3 bispecific T-cell engager for the treatment of multiple myeloma induces selective lysis in vitro and in vivo

A novel BCMA/CD3 bispecific T-cell engager for the treatment of multiple myeloma induces selective lysis in vitro and in vivo Leukemia advance online publication, January 13 2017. doi:10.1038/leu.2016.388 Authors: S Hipp, Y-T Tai, D Blanset, P Deegen, J Wahl, O Thomas, B Ratte ... more

A TLR7 agonist enhances the antitumor efficacy of obinutuzumab in murine lymphoma models via NK cells and CD4 T cells

A TLR7 agonist enhances the antitumor efficacy of obinutuzumab in murine lymphoma models via NK cells and CD4 T cells Leukemia advance online publication, January 3 2017. doi:10.1038/leu.2016.352 Authors: E J Cheadle, G Lipowska-Bhalla, S J Dovedi, E Fagnano, C Klein, J Honeyc ... more

Corrigendum: Quantifying the shifting landscape of B cell immunodominance

Nature Immunology 18, 705 (2017). doi:10.1038/ni0617-705a Author: Gordon A Dale, Jessica R Shartouny & Joshy Jacob more

Super-resolution microscopy with DNA-PAINT

Nature Protocols 12, 1198 (2017). doi:10.1038/nprot.2017.024 Authors: Joerg Schnitzbauer, Maximilian T Strauss, Thomas Schlichthaerle, Florian Schueder & Ralf Jungmann Super-resolution techniques have begun to transform biological and biomedical research by allowing resea ... more

Erratum: Epigenetic landscapes reveal transcription factors that regulate CD8+ T cell differentiation

Nature Immunology 18, 705 (2017). doi:10.1038/ni0617-705b Author: Bingfei Yu, Kai Zhang, J Justin Milner, Clara Toma, Runqiang Chen, James P Scott-Browne, Renata M Pereira, Shane Crotty, John T Chang, Matthew E Pipkin, Wei Wang & Ananda W Goldrath more

All publications

The sole LSm complex in Cyanidioschyzon merolae associates with pre-mRNA splicing and mRNA degradation factors [ARTICLE]

Proteins of the Sm and Sm-like (LSm) families, referred to collectively as (L)Sm proteins, are found in all three domains of life and are known to promote a variety of RNA processes such as base-pair formation, unwinding, RNA degradation, and RNA stabilization. In eukaryotes, (L)Sm proteins ... more

Crystal structure of U2 snRNP SF3b components: Hsh49p in complex with Cus1p-binding domain [ARTICLE]

Spliceosomal proteins Hsh49p and Cus1p are components of SF3b, which together with SF3a, Msl1p/Lea1p, Sm proteins, and U2 snRNA, form U2 snRNP, which plays a crucial role in pre-mRNA splicing. Hsh49p, comprising two RRMs, forms a heterodimer with Cus1p. We determined the crystal structures ... more

Comprehensive processing of high-throughput small RNA sequencing data including quality checking, normalization, and differential expression analysis using the UEA sRNA Workben ...

Recently, high-throughput sequencing (HTS) has revealed compelling details about the small RNA (sRNA) population in eukaryotes. These 20 to 25 nt noncoding RNAs can influence gene expression by acting as guides for the sequence-specific regulatory mechanism known as RNA silencing. The incre ... more

A new cis-acting motif is required for the axonal SMN-dependent Anxa2 mRNA localization [ARTICLE]

Spinal muscular atrophy (SMA) is caused by mutations and/or deletions of the survival motor neuron gene (SMN1). Besides its function in the biogenesis of spliceosomal snRNPs, SMN might possess a motor neuron specific role and could function in the transport of axonal mRNAs and in the modula ... more

U7 snRNP is recruited to histone pre-mRNA in a FLASH-dependent manner by two separate regions of the stem-loop binding protein [ARTICLE]

Cleavage of histone pre-mRNAs at the 3' end requires stem–loop binding protein (SLBP) and U7 snRNP that consists of U7 snRNA and a unique Sm ring containing two U7-specific proteins: Lsm10 and Lsm11. Lsm11 interacts with FLASH and together they bring a subset of polyadenylation factors to U ... more

All publications on biotechnology

Issue Information

No abstract is available for this article. more

Association of maternal serum PAPP‐A levels, nuchal translucency and crown rump length in first trimester with adverse pregnancy outcomes: Retrospective cohort study

Abstract Objective Are first trimester serum pregnancy‐associated plasma protein‐A (PAPP‐A), nuchal translucency (NT) and crown rump length (CRL) prognostic factors for adverse pregnancy outcomes? Method Retrospective cohort women, singleton pregnancies (UK 2011‐2015). Unadjuste ... more

The three‐vessels and trachea view (3VTV) in the first trimester of pregnancy: an additional tool in screening for congenital heart defects (CHD) in an unselected population.

Abstract Objective The aim of the study was to evaluate the feasibility of obtaining the 3VTV in an unselected population undergoing first trimester screening for aneuploidy, and to investigate its role in the early detection of CHD. Methods Cardiac examination was performed by ... more

Crossed ectopic kidney: prenatal diagnosis and postnatal follow‐up.

Objective To investigate prenatal diagnosis and postnatal outcome of fetuses with crossed ectopic kidney Methods Cases referred for an empty renal fossa and diagnosed with crossed ectopic kidney confirmed postnatally were analyzed retrospectively over a period of 10 years. Prenatal ... more

Recommended practice for laboratory reporting of non‐invasive prenatal testing (NIPT) of trisomies 13, 18 and 21: a consensus opinion

ABSTRACT Objective NIPT for trisomies 13, 18, and 21 is used worldwide. Laboratory reports should provide clear, concise results with test limitations indicated, yet no national or local guidelines are currently available. Here we aim to present minimum best practice guidelines. M ... more

All publications on diagnostics

Inside the USCAP Journals

Inside the USCAP Journals Laboratory Investigation 97, 492 (May 2017). doi:10.1038/labinvest.2017.38 more

The evolving concept of cancer stem-like cells in thyroid cancer and other solid tumors

The evolving concept of cancer stem-like cells in thyroid cancer and other solid tumors Laboratory Investigation advance online publication, April 10 2017. doi:10.1038/labinvest.2017.41 Authors: Heather Hardin, Ranran Zhang, Holly Helein, Darya Buehler, Zhenying Guo & Ricardo ... more

Inside the USCAP Journals

Inside the USCAP Journals Laboratory Investigation 97, 354 (April 2017). doi:10.1038/labinvest.2017.27 more

T-lymphocyte homing: an underappreciated yet critical hurdle for successful cancer immunotherapy

T-lymphocyte homing: an underappreciated yet critical hurdle for successful cancer immunotherapy Laboratory Investigation advance online publication, March 27 2017. doi:10.1038/labinvest.2017.25 Authors: Robert Sackstein, Tobias Schatton & Steven R Barthel more

The master role of microphthalmia-associated transcription factor in melanocyte and melanoma biology

The master role of microphthalmia-associated transcription factor in melanocyte and melanoma biology Laboratory Investigation advance online publication, March 6 2017. doi:10.1038/labinvest.2017.9 Authors: Akinori Kawakami & David E Fisher more

All publications on lab technology

Acute D3 Antagonist GSK598809 Selectively Enhances Neural Response During Monetary Reward Anticipation in Drug and Alcohol Dependence

Acute D3 Antagonist GSK598809 Selectively Enhances Neural Response During Monetary Reward Anticipation in Drug and Alcohol Dependence Neuropsychopharmacology 42, 1559 (June 2017). doi:10.1038/npp.2017.47 Authors: Anna Murphy, Liam J Nestor, John McGonigle, Louise Pater ... more

NPP: Our Designs for the Future

NPP: Our Designs for the Future Neuropsychopharmacology 42, 1371 (June 2017). doi:10.1038/npp.2017.54 Authors: William A Carlezon & Anissa Abi-Dargham Keywords: more

Memories of Opiate Withdrawal Emotional States Correlate with Specific Gamma Oscillations in the Nucleus Accumbens

Memories of Opiate Withdrawal Emotional States Correlate with Specific Gamma Oscillations in the Nucleus Accumbens Neuropsychopharmacology 42, 1558 (June 2017). doi:10.1038/npp.2017.46 Authors: Cyril Dejean, Mathieu Sitko, Paul Girardeau, Amine Bennabi, Stéphanie Caill ... more

Poly(vinyl alcohol)/hydroxyapatite Monolithic In-Needle Extraction (MINE) device: Preparation and examination of drug affinity

Publication date: 15 July 2017 Source:European Journal of Pharmaceutical Sciences, Volume 105 Author(s): Monika Pietrzyńska, Michał Czerwiński, Adam Voelkel Polymer-ceramic materials based on poly(vinyl alcohol) (PVA) and hydroxyapatite were applied as sorption material in Monol ... more

Effective antimicrobial activity of a peptide mutant Cbf-14-2 against penicillin-resistant bacteria based on its unnatural amino acids

Publication date: 15 July 2017 Source:European Journal of Pharmaceutical Sciences, Volume 105 Author(s): Wei Kang, Hanhan Liu, Lingman Ma, Mengxiao Wang, Shanshan Wei, Pengbo Sun, Meiling Jiang, Min Guo, Changlin Zhou, Jie Dou Broad spectrum activities, a unique mo ... more

All publications on pharma

A novel BCMA|[sol]|CD3 bispecific T-cell engager for the treatment of multiple myeloma induces selective lysis in vitro and in vivo

A novel BCMA/CD3 bispecific T-cell engager for the treatment of multiple myeloma induces selective lysis in vitro and in vivo Leukemia advance online publication, January 13 2017. doi:10.1038/leu.2016.388 Authors: S Hipp, Y-T Tai, D Blanset, P Deegen, J Wahl, O Thomas, B Ratte ... more

A TLR7 agonist enhances the antitumor efficacy of obinutuzumab in murine lymphoma models via NK cells and CD4 T cells

A TLR7 agonist enhances the antitumor efficacy of obinutuzumab in murine lymphoma models via NK cells and CD4 T cells Leukemia advance online publication, January 3 2017. doi:10.1038/leu.2016.352 Authors: E J Cheadle, G Lipowska-Bhalla, S J Dovedi, E Fagnano, C Klein, J Honeyc ... more

Corrigendum: Quantifying the shifting landscape of B cell immunodominance

Nature Immunology 18, 705 (2017). doi:10.1038/ni0617-705a Author: Gordon A Dale, Jessica R Shartouny & Joshy Jacob more

Erratum: Epigenetic landscapes reveal transcription factors that regulate CD8+ T cell differentiation

Nature Immunology 18, 705 (2017). doi:10.1038/ni0617-705b Author: Bingfei Yu, Kai Zhang, J Justin Milner, Clara Toma, Runqiang Chen, James P Scott-Browne, Renata M Pereira, Shane Crotty, John T Chang, Matthew E Pipkin, Wei Wang & Ananda W Goldrath more

Erratum: THEMIS enhances TCR signaling and enables positive selection by selective inhibition of the phosphatase SHP-1

Nature Immunology 18, 705 (2017). doi:10.1038/ni0617-705c Author: Seeyoung Choi, Claude Warzecha, Ekaterina Zvezdova, Jan Lee, Jérémy Argenty, Renaud Lesourne, L Aravind & Paul E Love more

All publications on healthcare
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