Protein Interactions

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“Inject the sam®X factor into your protein research”

With a sam®X biosensor you can perform a range of protein binding studies, using adjustable fluidics to increase flexibility, throughput and accuracy more

News Protein Interactions

• Plate reader for drug discovery
  

  The trend towards automated high content assays, particularly for systems biology and drug discovery, has stimulated the development of automated fluorescence microscopy systems to image sample arrays. Today’s commercially available high content analysis (HCA) instruments predominantly employ fluore more

• Control of cellular recycling pathways
  

  Together with researchers from the University of Rome/Italy and the Italian National Institute for Infectious Diseases scientists from the Freiburg Institute for Advanced Studies (FRIAS) and the Center for Biological Systems Analysis (ZBSA) shed light onto the highly organized and complicated regula more

• SYGNIS is granted the European and US patent for a very versatile and efficient drug screening platform

  SYGNIS Pharma AG has been granted the European and US patent for a new basic technology for the detection of protein-protein interactions, a screening platform for the development of novel drugs.  Protein-protein interactions falls within the scope of proteomics, a field that is growing in importanc more

White papers Protein Interactions

• RealTime ready qPCR Assay Design and Configuration Portal Content
  

  The gene and transcript annotational content of the RealTime ready Configurator offers a combined view of three of the main gene annotation authorities. The positional information of the lab-tested RealTime ready assays regarding transcript or exon coverage is presented in a graphical overview and tabular format. Additional content provides a convenient and browsable entry point for target gene selection for cataloged as well as new assays that are developed on demand more

Publications Protein Interactions

• Native cysteine residues are dispensable for the structure and function of all five yeast mitotic septins

  ABSTRACT Budding yeast septins assemble into hetero‐octamers and filaments required for cytokinesis. Solvent‐exposed cysteine (Cys) residues provide sites for attaching substituents useful in assessing assembly kinetics and protein interactions. To introduce Cys at defined locations, site‐direct more

• Pathogenic NPHP5 mutations impair protein interaction with Cep290, a prerequisite for ciliogenesis

  Mutations in the human NPHP5 gene cause retinal and renal disease, but the precise mechanism by which NPHP5 functions is not understood. We report that NPHP5 is a centriolar protein whose depletion inhibits an early step of ciliogenesis, a phenotype reminiscent of Cep290 loss and contrary to IFT88 more

• A multi-layer inference approach to reconstruct condition-specific genes and their regulation

  An important topic in systems biology is the reverse engineering of regulatory mechanisms through reconstruction of context-dependent gene networks. A major challenge is to identify the genes and the regulations specific to a condition or phenotype, given that regulatory processes are highly connec more

Market studies Protein Interactions

• Hybrigenics S.A. (ALHYG) - Financial and Strategic SWOT Analysis Review

  Hybrigenics S.A. (ALHYG) - Financial and Strategic SWOT Analysis Review Summary Hybrigenics S.A. (Hybrigenics) is a France-based bio-pharmaceutical company engaged in discovery and development of therapies for the treatment of cancer and commercialization of its technology and bioinformatics platf more

Websites Protein Interactions