SmartExtraction – nucleic acid extraction with superb yields in terms of both quality and quantity Extraction of high-molecular-weight DNA
- Nucleic acid extraction is quicker, more efficient, and more easily to be automated
- Purifying is easier than ever before – the usual tools are no longer needed
- Simple procedure, extremely easy to automate
Nucleic acid isolation and purification are among the most widespread laboratory methods worldwide. Along with the process for isolating nucleic acids using phenol/chloroform or ion exchangers, the method for the extraction of nucleic acids and binding them to the mineral solid phase has established itself everywhere.
Analytik Jena offers a global innovation in nucleic acid extraction: The innovative SmartExtraction technology does not require the use of phenol/chloroform, ion exchangers, filter columns, or filter plates, nor does it need suspensions from magnetic or paramagnetic particles for the binding of nucleic acids. The use of innovatively modified surfaces for the binding of nucleic acids (“Smart Modified Surfaces”) forms the basis of the technology developed by scientists at Analytik Jena.
SmartExtraction can be used manually, automated, or used under field conditions. All the necessary extraction steps have been significantly simplified and sped up.
Along with its simple extraction process, the SmartExtraction technology also impresses in terms of the yield and quality of the isolated nucleic acids. Because of the extremely high binding capacities of the modified surfaces used, the achieved yield of nucleic acids is practically unlimited, as opposed to magnetic particle based extraction, for example. In addition, the new technology also allows the isolation of nucleic acids that are only present in very low concentrations in a biological sample.
Because of its universality, SmartExtraction can be implemented with all commonly used automated pipetting systems. Thus, the user will be granted the utmost freedom in choosing automated extraction systems. Apart from this, Analytik Jena also offers a number of hardware solutions for the isolation of nucleic acids using SmartExtraction technology with its InnuPure® C16, InnuPure® C96, CyBio® SELMA, CyBio® FeliX, and GeneTheatre automation platforms. These range from partially automated extraction protocols (CyBio SELMA) to fully automated extraction, which can then be combined with further process steps, such as a PCR setup (CyBio FeliX, GeneTheatre).
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