My watch list  

Direct PCR-based identification of bacteraemia and fungaemia in antibiotic-treated patients

Highly sensitive 16S/18S-based direct test for routine identification of bacteria and fungi

SepsiTest/UMD-Universal to identify your target

SepsiTest/UMD-Universal for tissue and body fluids

SepsiTest/UMD-Universal for orthopedic sample and lung infection

SepsiTest/UMD-Universal for neurological infections

SepsiTest/UMD-Universal to identify your target

CE IVD-marked SepsiTest™ is currently the only direct molecular diagnostic test which identifies far more than the most common blood pathogens.

SepsiTest™ relies on universal 16S/18S rRNA gene PCR and sequencing which identifies more than 345 bacteria and fungi.

As a supplement to SepsiTest™, Universal Microbe Detection, including UMD-Tissue, UMD-Liquid, UMD-Swab, UMD-Universal kits enable next to blood also the diagnosis of other body fluids, tissues, swabs and biofilms:

  • Body fluids
    • Blood
    • Synovial fluid
    • Cerebrospinal fluid
    • Ascites fluid
    • Bronchoalveolar lavage
    • Pleural fluid
    • Blood culture
    • Smear
    • Abscesses
    • Tissues
      • Heart valve
      • Liver biopsies
      • Brain biopsies and others


SepsiTest™ is an “all-in-one” kit concept, including buffers, reagents and tubes necessary for DNA extraction and PCR/Real-Time PCR analysis. The consumables are guaranteed free of contaminating microbial DNA. No more than standard molecular laboratory equipment is needed to perform the test. Optionally, automated versions, SepsiTest™ SelectNA and UMD-SelectNA, are available for the extraction of microbial DNA from various specimens. SepsiTest™ SelectNA and UMD-SelectNA substantially reduce hands-on-time and the risk of contamination by handling.


  1. Removal of human DNA and free floating DNA from dead microorganisms
  2. Isolation of enriched bacterial and fungal DNA
  3. Detection: In two separate reactions, bacterial and fungal DNAs are detected by 16S and 18S rRNA gene PCR or Real-Time PCR
  4. Sequence analysis of amplicons from positive PCR testing is aided by a free online BLAST tool.

The tool ( is based on more than 7,000 quality-controlled sequence entries of the 16S/18S rRNA genes making identification of bacterial, Candida spp., Cryptococcus spp., and Aspergillus spp. very precise.


Spiking experiments show high analytical sensitivities of pathogens. For instance, sensitivities of Staphylococcus aureus and Candida albicans are <20 cfu/ml and <10 cfu/ml blood, respectively.

A number of studies, including the diagnosis of sepsis, endocarditis, meningitis and other diseases have proven that, compared with blood culture, SepsiTest™/UMD show good diagnostic values ​​and identify non-growing pathogens in patients who are treated with antibiotics and are blood culture-negative.

If you need more detailed information, a publication record, a first user trial offer or a presentation in your laboratory, please contact the Molzym support team.

Request information now or download our brochure.

We are happy to answer your questions by phone at +49 (0) 421 / 594 977-30

More about Molzym
Your browser is not current. Microsoft Internet Explorer 6.0 does not support some functions on Chemie.DE