Topic process development

Companies process development

IBA GmbH, Germany

IBA GmbH – the "TAGnology” company Being one of the foremost providers of tag-derived products and services the ”TAG-company” IBA GmbH is covering the entire production process of recombinant proteins including cloning, transfection, protein expression and purification to detection, assay and immo more

instrAction GmbH, Germany

instrAction, located at the BASF site in Ludwigshafen, is develops and manufactures stationary phases based on the innovative, patent protected instrAction® technology. instrAction phases allow the efficient and highly selective industrial purification of pharmaceutical ingredients over a broad rang more

Products process development

Simple process architecture, easy operation - Single Column SMB Chromatography

SMB chromatography is widely associated with multiple columns, complex set-up and difficult handling. The Vogelbusch single column unit shows SMB can be different. more

News process development

• Novasep opens new 2,000 m2 expanded Shanghai facilities to meet increasing East Asia demand

  Novasep announced the opening of a new 2,000 m2 facility in Shanghai Pudong district, China. The site will boost Novasep's process development and engineering capabilities to cater for ever-increasing Chinese and East Asian demand. These facilities will also add to Novasep’s existing 12 global synth more

• Dr Barry Buckland Joins the Mucosis Supervisory Board

  Mucosis B.V. announced that Dr. Barry Buckland was elected to its Supervisory Board. Dr Buckland brings extensive experience in vaccine design and development. From 1996 to 2009, Dr. Buckland was Vice President, BioProcess R&D at Merck & Co, Inc. He built the unit and was responsible for process de more

• BioSystem Development and BAC BV collaborate to bring purification ligands to high throughput biotherapeutic process development

  BioSystem Development and BAC BV announced a collaboration to bring state-of-the-art high affinity ligands to the AssayMAP high-throughput micro-chromatography platform. This collaboration marks an essential objective toward growing a family of high-throughput tools for micro-scale purification and more

White papers process development

• Increased productivity for downstream processing of biotherapeutics
  

  Polymer-based chromatographic resins featuring high mechanical and chemical stability and high protein binding capacities can help to increase the throughput and robustness of biopharmaceutical manufacturing processes. Advances in genetic engineering and cell culture technology have raised upstream productivity in the production of recombinant proteins. Increased titres of up to 10 g/l stress the need for highly efficient and robust downstream processes (DSP). Most industrial bioprocess development groups apply generic DSP platforms that are designed to purify various candidates of the same class of proteins applying the same process design. Besides various filtration and virus inactivation steps, they usually involve two or three chromatographic unit operations with orthogonal separation modes. The use of high capacity chromatographic resins can help to overcome the DSP bottleneck by increasing process throughput and robustness more

• New Products for Cell Culture Analysis from Roche Innovatis
  

  The Roche Innovats product line is now available from Roche Applied Sciences. Below is a short introduction to three Roche Innovatis product lines designed for the complete analysis of cell cultures, from the simple determination of cell concentration to complex cellular screening. More information about Roche Innovatis products will appear in future issues of Biochemica more

• Alliances in Drug Discovery - The Chemical Element
  

  Alliances have evolved into a critical cornerstone of R&D strategy in the global pharmaceutical industry. No other industry has been leveraging this business model as successfully as the global pharmaceutical industry in its drive for innovation and success. Over three thousand deals amounting to a cumulative payout of US$ 17bn have been signed by pharmaceutical and biotech players in a span of two decades. In the past five years the industry's mania to develop new generation blockbuster drugs has taken on a new sense of urgency as 64% of the alliance value was inked and paid out during the period. more

Publications process development

• Vaccine process technology

  Abstract The evolution of vaccines (e.g., live attenuated, recombinant) and vaccine production methods (e.g., in ovo, cell culture) are intimately tied to each other. As vaccine technology has advanced, the methods to produce the vaccine have advanced and new vaccine opportunities have been creat more

• A lectin‐based gold nanoparticle assay for probing glycosylation of glycoproteins

  Abstract We report a glycoanalysis method in which lectins are used to probe the glycans of therapeutic glycoproteins that are adsorbed on gold nanoparticles. A model mannose‐presenting glycoprotein, ribonuclease B (RNase B), and the therapeutic monoclonal antibody (mAb) rituximab, were found to more

• Optical sensor enabled rocking T‐flasks as novel upstream bioprocessing tools

  Abstract During the past decade, novel disposable cell culture vessels (generally referred to as Process Scouting Devices or PSDs) have become increasingly popular for laboratory scale studies and seed culture generation. However, the lack of engineering characterization and online monitoring too more

Market studies process development

• NGL Fine-chem Ltd. - Strategic SWOT Analysis Review

  NGL Fine-chem Ltd. (NGL) is a publicly held pharmaceutical company. It is principally engaged in the manufacture of pharmaceutical ingredients and intermediate products that are used in animal and human health. The company's products include finished dosage forms, diminazene aceturate granules and h more

• European Photochromic Lenses Market to 2017 - Enhanced Vision Quality and End-User Convenience Increases Demand

  GBI Research’s report, “European Photochromic Lenses Market to 2017 - Enhanced Vision Quality and End-User Convenience Increases Demand” provides key data, information and analysis on the photochromic lenses market in Europe. The report provides a market landscape, key company profiles and market tr more

• Anu's Laboratories Limited (532981) - Financial and Strategic SWOT Analysis Review

  Anu's Laboratories Limited (Anu's Laboratories) is involved in the production of drug intermediates. The company offers basic and advanced intermediates, as well as fine chemicals. Some of the basic intermediates offered by the company includes 2,4 dichloro 5-fluoro acetophenone, 3'-chloro propiophe more

Websites process development