Peptides

Companies Peptides

MP Biomedicals S.A.S., France

MP Biomedicals is a global corporation, with headquarters in Santa Ana, California, USA and regional offices in Europe, Asia Pacific and Australia. The corporation manufactures and sells more than 55,000 ISO, FDA and CE certified products and is represented on all continents: NA, LATAM, APAC and EME more

Miltenyi Biotec GmbH, Germany

Miltenyi Biotec is a global provider of products and services that advance biomedical research and cellular therapy. Since 1989, we have developed innovative and reliable technologies for scientists and clinicians around the world. Our integrated portfolio of tools covers techniques of sample prepar more

BIOTREND Chemikalien GmbH, Germany

BIOTREND was instigated in order to meet the growing demand from customers for an independent and technologically orientated distribution facility offering high quality, yet cost-effective products for biochemical, immunochemical and pharmaceutical research. Through our innovative strength we are n more

Products Peptides

Merck Millipore: Reliable peptide synthesis

With a comprehensive product portfolio, Merck Millipore covers the entire peptide synthesis process: production, purification and identification. more

News Peptides

• Proteome atlas for the tuberculosis pathogen

  Photographers know the problem all too well: with the naked eye, you can see which branch a bird is sitting on, but spotting the bird in the blur of branches through the telephoto lens for high-magnification images requires considerable skill. It is a similar story for researchers who are looking to more

• Blockade of pathogen's metabolism
  

  In the search for new antibiotics, researchers are taking an unusual approach: They are developing peptides, short chains of protein building blocks that effectively inhibit a key enzyme of bacterial metabolism. Now, scientists at the Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) i more

• BRAIN expands its IP Portfolio with bioactive Compound MMPI

  BRAIN AG has announced the expansion of its IP portfolio to include the MMPI (matrix metalloproteinase inhibitor) peptide. Now owned by BRAIN, the recombinant human bioactive molecule will be manufactured by BRAIN as a proprietary bioactive compound going forward and exclusively used in cosmetics pr more

White papers Peptides

• Epitope Mapping Using the In Vitro Rapid Translation System RTS 100
  

  The Rapid Translation System (RTS) represents a cell-free system that allows efficient production of protein from linear DNA sequences. This article gives a brief outline of the use of the RTS technology in linear epitope mapping and shows its promise for reducing time-consuming cloning and cell-lysis steps. more

• Characterizing Biotherapeutics with HPLC
  

  As demonstrated here, there are a broad range of HPLC applications used in development, production, validation and release of protein therapeutics for human use. Some of the applications mentioned above are mandatory when submitting a new biopharmaceutical to approval at the regulatory agencies. The introduction of the first so-called biosimilars in Europe further increased the demand for highly efficient analysis methods. The continuous development of new stationary phases for the common modes of biochromatography, such as size exclusion, ion exchange and hydrophilic interaction chromatography support biochemists in increasing lab productivity and establishing high-throughput HPLC analysis not only for small molecules but also for large biopolymers more

• Increased productivity for downstream processing of biotherapeutics
  

  Polymer-based chromatographic resins featuring high mechanical and chemical stability and high protein binding capacities can help to increase the throughput and robustness of biopharmaceutical manufacturing processes. Advances in genetic engineering and cell culture technology have raised upstream productivity in the production of recombinant proteins. Increased titres of up to 10 g/l stress the need for highly efficient and robust downstream processes (DSP). Most industrial bioprocess development groups apply generic DSP platforms that are designed to purify various candidates of the same class of proteins applying the same process design. Besides various filtration and virus inactivation steps, they usually involve two or three chromatographic unit operations with orthogonal separation modes. The use of high capacity chromatographic resins can help to overcome the DSP bottleneck by increasing process throughput and robustness more

Publications Peptides

• Evolutionary Analysis of the Contact System Indicates that Kininogen Evolved Adaptively in Mammals and in Human Populations

  Activation of the contact system leads to the cleavage of kininogen by plasma kallikrein resulting in kinin release and in the initiation of the intrinsic pathway of coagulation. Proteolysis of kininogen also generates antimicrobial peptides (AMPs) and can be induced by diverse pathogens. Thus, the more

• Expression of a novel mRNA transcript for human microsomal epoxide hydrolase (EPHX1) is regulated by short open reading frames within its 5'-untranslated region [ARTICLES]

  Microsomal epoxide hydrolase (mEH, EPHX1) is a critical xenobiotic-metabolizing enzyme, catalyzing both detoxification and bioactivation reactions that direct the disposition of chemical epoxides, including the carcinogenic metabolites of several polycyclic aromatic hydrocarbons. Recently, we disco more

• Synthesis, characterisation and biological evaluation of 99mTc(CO)3 labeled peptides for potential use as tumor targeted radiopharmaceuticals

  Abstract During the past decade several peptides containing RGD sequence have been conjugated with different chelating agents for labeling with various radionuclides for the diagnosis of tumor development. In this study we report the synthesis of two tetra peptides (Asp‐Gly‐Arg‐His and Asp‐Gly‐A more

Market studies Peptides

• Miraculins Inc. - Strategic SWOT Analysis Review

  Miraculins Inc (Miraculins) is a research and development company engaged in the discovery and validation of cancer biomarkers, which enable the development of diagnostic tools and therapeutic products. The company focuses on biomarker discovery using its proprietary B.E.S.T Platform for the screeni more

• DelSite Biotechnologies, Inc. - Strategic SWOT Analysis Review

  DelSite Biotechnologies, Inc. is an early stage drug-delivery and biotechnology company established to provide the pharmaceutical and biotechnology industries with drug delivery solutions for new and existing proteins and peptides. The company's Carrington division is engaged in wound care managemen more

• Oral Drug Delivery Market to 2017 - Out-licensing Proprietary Technologies for Proteins, Peptides and Small Molecules to Drive Revenue Growth

  GBI Research, the leading business intelligence provider, has released its latest research “Oral Drug Delivery Market to 2017 - Out-licensing Proprietary Technologies for Proteins, Peptides and Small Molecules to Drive Revenue Growth”. The report focuses on the current scenario of orally administere more

Websites Peptides