OGT

News OGT

• OGT opens New York office and appoints US sales team

  Oxford Gene Technology (OGT) announced that it has opened a new office in Tarrytown, New York to support and grow its cytogenetics arrays and next generation sequencing business in the US.The new office will enable OGT to provide hands-on technical support and training to its existing US customers, more

• OGT founder Professor Sir Ed Southern awarded the 2011 MRC Millennium Medal
  

  Professor Sir Ed Southern, founder of Oxford Gene Technology (OGT) has been awarded the 2011 Medical Research Council (MRC) Millennium Medal. Sir Ed becomes one of only four researchers to have received the prize since it was inaugurated in the year 2000, which recognises an MRC-funded scientist who more

• OGT to develop tumour profiling assay to facilitate personalised cancer treatment

  Oxford Gene Technology (OGT) has announced that it has received a funding award of £1.16 million from the UK government-backed Technology Strategy Board. As part of the project, OGT will develop a tumour profiling assay based on targeted panel enrichment and next generation sequencing (NGS). The new more

Publications OGT

• Proteomic analysis and abrogated expression of O‐GlcNAcylated proteins associated with primary breast cancer

  O‐GlcNAcylation is a dynamic posttranslational modification of nuclear and cytoplasmic proteins, regulated by O‐GlcNAc transferase (OGT) and O‐GlcNAcase (OGA), which catalyze the addition and removal of O‐GlcNAc, respectively. This modification is associated with glucose metabolism, which plays im more

• O-GlcNAc transferase (OGT) as a placental biomarker of maternal stress and reprogramming of CNS gene transcription in development [Neuroscience]

  Maternal stress is a key risk factor for neurodevelopmental disorders, including schizophrenia and autism, which often exhibit a sex bias in rates of presentation, age of onset, and symptom severity. The placenta is an endocrine tissue that functions as an important mediator in responding to perturb more

• O-GlcNAc processing enzymes: catalytic mechanisms, substrate specificity, and enzyme regulation

  December 2012 Publication year: 2012Source:Current Opinion in Chemical Biology, Volume 16, Issues 5–6 The addition of N-acetylglucosamine (GlcNAc) O-linked to serine and threonine residues of proteins is known as O-GlcNAc. This post-translational modification is found within multicellul more

Websites OGT