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News NIH

• Bix of Sanders-Brown receives NIH funding for stroke research

  Dr. Gregory Bix, Paul G. Blazer J. Professor of Stroke Research in the University of Kentucky Sanders-Brown Center on Aging and the UK departments of Anatomy and Neurobiology and Neurology, has received funding of $224,416 from the National Institutes of Health, to further study of stroke recovery. more

• Margaret Gourlay wins Top 10 Clinical Research Achievement Award from Clinical Research Forum
  

  For leading a study that was the first to define appropriate bone density screening intervals for older women, Margaret Gourlay, MD, MPH, of the University of North Carolina School of Medicine has been honored with a Top 10 Clinical Research Achievement Award from the Clinical Research Forum. The wi more

• Recipe for large numbers of stem cells requires only one ingredient

  Stem cells and tissue-specific cells can be grown in abundance from mature mammalian cells simply by blocking a certain membrane protein, according to scientists at the University of Pittsburgh School of Medicine and the National Institutes of Health (NIH). Their experiments, reported today in Scien more

White papers NIH

• The xCELLigence System: Label-Free Measurement of Natural Killer Cell Cytotoxic Activity in Real Time
  

  Natural killer (NK) cells have been implicated in the recognition and annihilation of tumor cells. The assessment of the cytolytic activity of NK cells is important not only for monitoring of immunocompetence in cancer, infectious diseases, and autoimmune diseases, but also in determining the proteins which mediate the cytolytic effect. more

• Quantification of BRCA1 Expression Level Using Standard RT-PCR Reagents - a Sensitive Method for the Detection of Low Amounts of Transcripts
  

  Mutations in the breast cancer susceptibility gene, BRCA1, occur in the majority of families with multiple members affected with breast or ovarian cancer. Women who inherit a BRCA1 mutation have 40%-80% risk of developing breast cancer or ovarian cancer. However, up to 90% of breast cancers are sporadic, and mutations in BRCA1 seem to be a rare event in sporadic breast tumors. more

• siRNA Silencing of Lamin A and Quantification of the Knockdown Effect via qPCR
  

  Lamins are structural proteins which form a thin fibrous layer called the nuclear lamina. Currently, three types of lamins are known in mammalian cells: lamin A, B, and C. Lamins may be involved in DNA replication, chromatin organization, differentiation, nuclear structural support, nuclear envelope reassembly, and several other processes. Mutations of lamin A can cause muscular dystrophy, dilated cardiomyopathy, familiar partial lipodystrophy [3], and other disorders. For the detailed analysis of the different functions of this more than 70 kDa large protein, the expression should be blocked. more

Publications NIH

• [Policy Forum] Research Priorities: The NIH BRAIN Initiative

  The NIH BRAIN Initiative will build on recent successes in neuroscience to create and apply new tools for understanding brain activity. more

• A clinical and genetic overview of 18 years Neurofibromatosis type 1 molecular diagnostics in the Netherlands

  Abstract NF1 mutations are the underlying cause of Neurofibromatosis type 1 (NF1), a neuro‐cardio‐facio‐cutaneous syndrome (NCFC). Because of the clinical overlap between NCFCs, genetic analysis of NF1 is necessary to confirm a clinical diagnosis NF1. The present report describes the clinical an more

• The science police

  Nature Medicine 19, 507 (2013). doi:10.1038/nm.3191 The publication of a controversial study by a US National Institutes of Health (NIH)-funded researcher suggesting a link between the Tea Party and the tobacco industry has brought the NIH under fire by Congress. But strict polic more

Market studies NIH

• Translational Regenerative Medicine - Oncology, CNS and Cardiovascular-Rich Pipeline Features Innovative Stem Cell and Gene Therapy Applications

  GBI Research, the leading business intelligence provider, has released its latest research, “Translational Regenerative Medicine - Oncology, CNS and Cardiovascular-Rich Pipeline Features Innovative Stem Cell and Gene Therapy Applications”, which provides insights into the global regenerative medicin more

• Immunovaccine, Inc. (IMV) - Financial and Strategic SWOT Analysis Review

  Immunovaccine, Inc. (IMV), formerly Rhino Resources Inc., is a clinical stage biotechnology company. The company operates all its business activities through its 100% owned subsidiary ImmunoVaccine Technologies Inc. It is specialized in developing premium vaccines for the treatment of therapeutic ca more

• Stem Cell Technologies: World Market Outlook 2011-2021

  How will the stem cells market develop this decade? Our new report shows you that emerging industry and market's revenue potential from 2011 to 2021. This report covers stem cells in therapeutic applications: technologies, products and services. You will assess events, opportunities and activities more

Websites NIH