Researchers isolate the substance that causes Venus flytraps to close

11-11-2010

The Venus flytrap is a carnivorous plant luring insect prey with drops of liquid. The trap snaps shut like a steel jaw when an insect touches one of the very fine hairs within. The prey is caught – digestion begins. Minoru Ueda and a research team from the Universities of Tohoku, Hirosaki, ...

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Animal study suggests a mutated protein in brain cells can lead to cardiac arrest in people with epilepsy

16-04-2010

A mutation in a brain protein gene may trigger irregular heart beat and sudden death in people with epilepsy, according to new research in The Journal of Neuroscience. People with epilepsy who are otherwise healthy are more than 10 times more likely to die suddenly and unexpectedly than the ...

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Study reveals mechanism that adjusts fat burning

08-01-2010

Mayo researchers collaborating with investigators at the University of Iowa, University of Connecticut and New York University (NYU) have discovered a molecular mechanism that controls energy expenditure in muscles and helps determine body weight. Researchers say this could lead to a new ...

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23-11-2009

Takeda Pharmaceutical Company Limited (announced that TAK-438, which is the drug for acid-related diseases, has entered into Phase II clinical trials for the treatment of patients with reflux esophagitis in Japan. TAK-438, originated by Takeda, is a potassium-competitive acid blocker that ...

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Two genes represent potential drug targets for both heart and endocrine disease

23-09-2009

Genes previously known to be essential to the coordinated, rhythmic electrical activity of cardiac muscle - a healthy heartbeat - have now also been found to play a key role in thyroid hormone (TH) biosynthesis, according to Weill Cornell Medical College researchers. The authors' findings, ...

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07-07-2009

XENTION LTD announced that it had received a substantial award from the Wellcome Trust to support pioneering work on an exciting target for atrial fibrillation. The award, made under Wellcome’s Seeding Drug Discovery initiative, will provide up to £3 million to fund Xention’s IKACh programme ...

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06-05-2009

Carnegie Mellon University researchers have identified a new anticonvulsant compound that has the potential to stop the development of epilepsy. The findings are published in the journal Epilepsia . The research discovery builds on previous work identifying a specific molecular target whose ...

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07-04-2009

Excess amounts of a naturally fluorescent molecule found in all living cells could serve as a natural biomarker for cancer, according to bioengineers. NADH, or nicotinamide adenine dinucleotide, is a key coenzyme found mostly in the inner membrane of a cell's power plant, or mitochondria. It ...

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Tufts study shows that changes in membrane voltage control timing of differentiation in adult stem cells

05-12-2008

Natural changes in voltage that occur across the membrane of adult human stem cells are a powerful controlling factor in the process by which these stem cells differentiate, according to research published by Tufts University scientists. Tufts doctoral student Sarah Sundelacruz, Professor of ...

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GSK to make upfront payment to Valeant of $125 million

01-09-2008

Valeant Pharmaceuticals International and GlaxoSmithKline (GSK) announced that they have entered into an exclusive worldwide collaboration agreement for the investigational drug retigabine, a first in class neuronal potassium channel opener for treatment of adult epilepsy patients with ...

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