17-05-2010

Anti-inflammatory drugs appear to help block the rapid kidney destruction that can occur with hypertension, Medical College of Georgia researchers report. Treating hypertensive rats with the broad-acting anti-inflammatory drug pentosan polysulfate preserves the kidney's ability to regulate ...

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06-05-2010

BELLUS Health announced that it will discontinue its NC-503 diabetes development program following the results of the recently completed Phase IIa clinical proof-of-concept study evaluating NC-503 (eprodisate disodium) as a treatment for Type 2 diabetes. The study did not meet its primary ...

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Study provides breakthrough blueprint for studying differentiation and evolution

08-03-2010

In a significant leap forward in the understanding of how specific types of tissue are determined to develop in mammals, an international team of scientists has succeeded in mapping the entire network of DNA-binding transcription factors and their interactions. This global network, indicating ...

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17-02-2010

Pharming Group NV announced publication of preclinical evidence that its recombinant human C1 inhibitor (rhC1INH) may play an important therapeutic role in the prevention of delayed graft function (DGF) after solid organ transplantation. The published study results further indicate the ...

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29-01-2010

A team of Florida State University researchers will use a five-year, $1.3 million grant from the National Institutes of Health to develop a way to measure levels of the trace metal zinc in the human body. Scientists have long known that zinc plays a critical role in numerous biochemical ...

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27-01-2010

Investigators have identified a new disease mechanism and therapeutic approach for a type of advanced kidney disease that is a common cause of complications in patients with lupus. The study was led by investigators at Hospital for Special Surgery and appears in Proceedings of the National ...

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09-11-2009

A key player in a cascade that likely begins with stress and leads to high blood pressure and kidney damage has been identified by researchers who say the finding may lead to better ways to control both. Medical College of Georgia researchers have found endothelin, a powerful blood vessel ...

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Scripps Research scientists correct gene defect in mice that causes lethal symptoms in children

21-09-2009

A recent study by Scripps Research Institute scientists offers good news for families of children afflicted with the rare genetic disorder, cystinosis. In research that holds out hope for one day developing a potential therapy to treat the fatal disorder, the study shows that the genetic ...

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07-08-2009

Rather than sticking to a single DNA script, human brain cells harbor astonishing genomic variability, according to scientists at the Salk Institute for Biological Studies. The findings, published in Nature, could help explain brain development and individuality, as well as lead to a better ...

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27-07-2009

New data collected at Columbia University Medical Center and by the Mount Sinai School of Medicine are helping researchers understand the extent to which a certain protein – NGAL – can play a significant role in marking chronic kidney disease resulting from HIV while at the same time ...

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