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27 Current news of Ruhr-Universität Bochum

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When wine hits the right nerve

Neither the sense of taste nor the sense of smell is responsible for barrique appreciation

07-05-2014

If wine leaves a bitter, cotton-like coating on the tongue, neither the sense of taste nor the sense of smell is responsible. The traditional oak barrel character, also called barrique character, is perceived via the trigeminal nerve, which is responsible for, among other things, pain and ...

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Small peptides as potential antibiotics

Research team decodes the effects of an antimicrobial peptide on bacterial cells

26-03-2014

Small peptides attack bacteria in many different ways and may well become a new generation of antibiotics. Biologists at the Ruhr-Universität Bochum (RUB) have been researching how such peptides kill bacterial cells. “It is quite possible that, in ten years time, all of the currently marketed ...

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A signal to survive: How the Parkin enzyme inhibits neuronal cell death

The Michael J. Fox Foundation supports new project at the RUB

02-01-2014

Cell biologists at the Ruhr-Universität Bochum (RUB) have launched a new project to unravel the role of the enzyme Parkin in promoting neuronal survival. The team of Prof Dr Konstanze F. Winklhofer from the Institute of Physiological Chemistry, Department of Molecular Cell Biology, is looking for ...

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Anti-epilepsy drugs can cause inflammations

Inflammatory reactions should be taken under consideration in drug selection

02-01-2014

Physicians at the Ruhr-Universität Bochum (RUB) have been investigating if established anti-epilepsy drugs have anti-inflammatory or pro-inflammatory properties – an effect for which these pharmaceutical agents are not usually tested. One of the substances tested caused stronger inflammations, ...

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The yin and yang in the life of proteins

Two opposing mechanisms regulate the transport of proteins in peroxisomes

24-10-2013

Recycling or “scrap press”: physicians at the Ruhr-Universität have found out which molecular mechanisms decide about the fate of the import receptor Pex18. Pex18 is responsible for the import of proteins into specific cell components, namely peroxisomes. Two opposing regulatory circuits ...

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The coelacanth leads a monogamous life

Research team analyses genetic make-up of two pregnant females

19-09-2013

Scientists have successfully analysed the genetic make-up of the offspring of pregnant coelacanth females for the first time. They found that the likelihood that the offspring is fathered by one single individual is very high – unlike with many other fish species. Analysis of the microsatellite ...

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Proteins hoist the anchor

How switch proteins are extracted from the membrane

07-08-2013

Researchers from the Ruhr-Universität Bochum (RUB) and from the MPI Dortmund have for the first time successfully reproduced the recycling process of proteins regulating cellular transport in a biophysical experiment. In doing so, they traced in detail the way the central switch protein Rab is ...

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How to learn successfully even under stress

Mineralocorticoid receptors ensure flexible engagement of learning strategies

31-07-2013

Whenever we have to acquire new knowledge under stress, the brain deploys unconscious rather than conscious learning processes. Neuroscientists at the Ruhr-Universität Bochum have discovered that this switch from conscious to unconscious learning systems is triggered by the intact function of ...

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Fishing in the sea of proteins

Composition of splicing complex in chloroplasts identified for the first time

03-07-2013

To convert a gene into a protein, a cell first crafts a blueprint out of RNA. One of the main players in this process has been identified by researchers led by Dr. Jessica Jacobs at the Ruhr-Universität Bochum. The team “fished” a large complex of proteins and RNA, which is involved in the ...

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How Alzheimer’s could occur

Protein spheres in the nucleus give wrong signal for cell division

12-04-2013

A new hypothesis has been developed by researchers in Bochum on how Alzheimer’s disease could occur. They analysed the interaction of the proteins FE65 and BLM that regulate cell division. In the cell culture model, they discovered spherical structures in the nucleus that contained FE65 and BLM. ...

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