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53 Current news of Ruhr-Universität Bochumrss
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Protein switches are active everywhere in the body and often affect the generation of diseases. Thanks to a special method, researchers from Bochum have gained new insights into their workings. Using a combination of infrared spectroscopy and computer simulation, researchers at Ruhr-Universität ...
Capsaicin, an active ingredient of pungent substances such as chilli or pepper, inhibits the growth of breast cancer cells. This was reported by a team headed by the Bochum-based scent researcher Prof Dr Dr Dr habil Hanns Hatt and Dr Lea Weber, following experiments in cultivated tumour cells. ...
This is how chemical processes could become more environmentally friendly
Chemical and biological catalysts tend to require very different reaction conditions, making their combination challenging. Researchers of the Ruhr-Universität Bochum have succeeded in taking this hurdle by using a special gel matrix to compartmentalize both types of catalysts. The results ...
The muscle cells of bronchi detect scents, for example a specific banana and apricot scent. This might be good news for asthma sufferers. Researchers identified two types of olfactory receptors in human muscle cells of bronchi. If those receptors are activated by binding an odorant, bronchi ...
Combination of experiment and theory gives insights
Some living organisms thrive under extraordinary conditions, such as the deep sea. But just how do they withstand the enormous pressure? Researchers at the Ruhr-Universität Bochum and the Technische Universität Dortmund have examined how the interactions between solvents and biomolecules change ...
Researchers from Bochum have engineered a hydrogen-producing enzyme in the test tube that works as efficiently as the original. The protein - a so-called hydrogenase from green algae - is made up of a protein scaffold and a cofactor. The latter is the reaction centre where the substances that ...
Switching specific G-protein-coupled signalling pathways on and off
Blue on, yellow off: using different-coloured light, researchers are able to switch signalling pathways in the brain on and off. Researchers in Bochum have utilised light-sensitive proteins from nerve cells of the eye – so-called melanopsins – to switch on specific signalling pathways in brain ...
Sustainable chemical processes
In order to manufacture chemical products in the industry, a high energy input is required, which consumes mainly our fossil resources. At RUB, two scientists are researching into a resource-efficient and, consequently, sustainable approach. Prof Dr Robert Kourist from the junior research group ...
Comparing cell and test tube
Researchers often analyse isolated biomolecules in test tubes, and it is doubtful if the results can be applied to densely-packed cells. A team from Bochum, Dortmund and Greifswald monitored the folding of an RNA structure in the living cell and compared the results with those of test tube ...
Altered activation pattern in entorhinal cortex in young risk carriers
Young adults with genetically increased Alzheimer’s risk have altered activation patterns in a brain region that is crucial for spatial navigation. This is reported by the team headed by Prof Nikolai Axmacher from the Ruhr-Universität Bochum, together with colleagues from the universities of ...