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Cold-blooded research has hearts thumping

23-04-2013

The protective effect of inducing controlled hypothermia following sudden cardiac arrest will now be investigated in detail. The goal of the scientific work is to judge whether this type of cryotherapy can be improved when using parallel simultaneous invasive resuscitation procedures. ...

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Skin-deep communication: Messenger substance and signaling molecule influence the development of the skin’s immune cells

01-02-2013

A signalling molecule known as Axl has been discovered on immune cells of the epidermis. This recently published finding provides new insight into the development of important skin immune cells known as Langerhans cells. These cells fight off invading microorganisms and play a crucial role in ...

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New Brain Protein

Surprising Discovery: Brain Variants of Protein Associated with Huntington's and Other Neurodegenerative Diseases Identified

25-07-2012

A protein essential for metabolism and recently associated with neurodegenerative diseases also occurs in several brain-specific forms. This discovery emerged in the course of a research project funded by the Austrian Science Fund FWF, the findings of which have now been published in the ...

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Biomay's grass pollen allergy vaccine shows efficacy in phase IIa trial

15-06-2012

Biomay AG announced promising results from a First-in-Man Phase IIa trial with its allergy vaccine BM32. The vaccine significantly reduced allergy-related nasal symptoms in a study group of 70 patients suffering from grass pollen allergy. The environmental challenge study also showed that ...

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First clinical trial for the Parkinson´s vaccine starts in Vienna

07-06-2012

AFFiRiS AG announced the start of the Phase I study of its Parkinson´s vaccine candidate PD01A. This vaccine represents the first agent worldwide aiming at disease modification of Parkinson´s rather than addressing symptomatic improvement only. PD01A targets a protein called alpha-Synuclein ...

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Implants: A better fit through mathematics

03-05-2012

Individuals with implants may soon be able to feel the benefit of basic scientific knowledge in their own bodies. This is one of the findings of a translational research project conducted by the Austrian Science Fund FWF. The project demonstrated how 3D models and special mathematical methods ...

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Immune cells with a killer instinct

Tried-and-tested anti-tumour drug displays new effect

29-03-2012

Imiquimod, a drug used to treat skin cancer, has been shown to have a previously unknown effect on immune cells. The drug transforms cells known as dendritic cells into "tumour killers" that attack the tumour directly and destroy its cells. The dendritic cells adopt an ingenious approach here ...

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Apeiron initiates clinical study to investigate prevention of radiation-induced skin damage in breast cancer patientes

29-02-2012

Apeiron Biologics AG announced that a clinical trial has started with the agent superoxide dismutase (project APN201) to investigate its potential for prevention of radiation dermatitis in breast cancer patients. Apeiron announced that a clinical trial has started with a liposomal topical ...

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Ovarian Cancer: New tumour suppressor gene identified

15-02-2012

A recent study published in Clinical Cancer Research suggests that the protein hVps37A suppresses tumour growth in ovarian cancer. The work, which was funded by the Austrian Science Fund FWF, shows, for the first time, that this protein is significantly reduced in ovarian cancer cells. The ...

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Start of Phase IIa study in acute lung injury patients marks development milestone for Apeiron's rhACE2

22-12-2011

Apeiron announced the initiation of a phase IIa clinical study of rhACE2, in patients with Acute Lung Injury (ALI). The study, of which Apeiron´s licensee GSK is sponsor, will include subjects with a positive diagnosis of ALI, and will be conducted in the intensive care units of multiple ...

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