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Childhood trauma could lead to adult obesity


Being subjected to abuse during childhood entails a markedly increased risk of developing obesity as an adult. This is the conclusion of a meta-analysis carried out on previous studies, which included a total of 112,000 participants. The analysis was conducted by researchers at Karolinska ...


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Why White Dogs are White


About half of all dogs show some form of white spotting which can range from a few white marks in the Bernese mountain dog to extreme white coat color in Dalmatians and white boxer. But why have dogs so often white markings, and how can we explain how they are determined genetically? This has ...


Stem cells from nerves form teeth


Researchers at Karolinska Institutet in Sweden have discovered that stem cells inside the soft tissues of the tooth come from an unexpected source, namely nerves. These findings are now being published in the journalNatureand contribute to brand new knowledge of how teeth are formed, how they ...


Pharmalink's core patents for Nefecon treatment for renal disease granted


Pharmalink AB has had core patents for its late-stage clinical candidate Nefecon® issued in the key markets United States, Europe, China and Hong Kong. A patent is pending in Japan.Nefecon is a potential disease-modifying treatment for patients with primary IgA nephropathy at risk of developing ...


Contradictory Findings about the Effect of the Full Moon on Sleep


According to folklore, the full moon affects human sleep. International researchers are trying to determine whether there is any truth to the belief. Studies by a team at The University of Gothenburg in Sweden have found that people actually sleep 20 minutes less when the moon is full. A Swiss ...


Sobi files for EU approval of Xiapex for Peyronies disease


Swedish Orphan Biovitrum AB (publ) (Sobi) and Auxilium Pharmaceuticals, Inc.announced that Sobi has filed for an extension of the label for Xiapex® (collagenase clostridium histolyticum) with the European Medicines Agency (EMA) to include the indication of Peyronie's disease.The filing is based ...


Karolinska Institutet dismisses link between suicidal behaviour and ADHD drugs


A new register-based study from Karolinska Institutet shows that drug therapy for ADHD does not entail an increased risk of suicide attempts or suicide, as was previously feared. The results are published in the British Medical Journal (BMJ).“Our work in several ways shows that most likely there ...


Possible New Combination Treatment for Cancer


Scientists at the Sahlgrenska Academy have developed a new cancer treatment that has proved to be effective in mice. The treatment, which is presented in PNAS, is based on newly discovered properties of the so-called BET bromodomain inhibitors.A few years ago, a molecule known as “JQ1” was ...


Unexpected origin for important parts of the nervous system


A new study from Karolinska Institutet in Sweden shows that a part of the nervous system, the parasympathetic nervous system, is formed in a way that is different from what researchers previously believed. In this study, a new phenomenon is investigated within the field of developmental biology, ...


Beactica Initiates Drug Discovery Collaboration with Medivir


Beactica, announced that it has entered into an agreement with Medivir AB. Under the agreement, Beactica will use its proprietary discovery platform to identify novel hits against a disease-relevant protease of therapeutic interest to Medivir. Financial terms of the agreement were not ...


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