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Are some people more likely to develop adverse reactions to nanoparticle-based medicines?


The complement system, the human body's first line of defense against blood-borne intruders, is blamed for infusion-related reactions to nanomedicines, but the conventional models used to predict the risk of cardiopulmonary side effects in response to nanopharmaceuticals might not well represent ...


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New patent on fast measurements in liquids


A new invention will open the doors for an entirely new way of measuring properties within liquids. The invention, a sol-gel matrix, will make it possible to perform measurements that are reliable, incredibly rapid and can be conducted over extended periods of time. The development will be a boon ...


Researchers develop novel cell line for screening of brain drugs


Researchers from the Department of Pharmacy at the University of Copenhagen have developed a cell line, which may be used to investigate new drugs and help predict whether they are able to enter the brain. The brain is protected by the so-called blood-brain barrier, a practically impermeable wall ...


Textbooks on cells should be rewritten


Ground-breaking new Danish research has shown that the current scientific description of the human cell cycle needs to be revised. These findings could also lead to the development of new therapeutic approaches to target an Achilles' heel in different types of cancers. All science students learn ...


Personally tailored diabetes care reduces mortality in women but not men


A follow-up study to assess the effects of personally tailored diabetes care in general practice has revealed that such care reduces mortality (both all-cause and diabetes-related), in women, but not men. The study is by Dr Marlene Krag, The Research Unit for General Practice, Department of ...


Genmab achieves USD 45 million milestone

Milestone triggered by first commercial sale of DARZALEX in the United States


Genmab A/S announced it has achieved a USD 45 million milestone in its DARZALEX™ (daratumumab) collaboration with Janssen Biotech, Inc. The milestone payment was triggered by the first commercial sale of DARZALEX in the United States. "Today marks a significant moment in the history of Genmab - ...


CMC Biologics appoints new CEO

Gustavo Mahler, COO & President at CMC Biologics, to Take the Helm January 1st 2016


CMC Biologics, Inc. announced the promotion of Gustavo Mahler, to be effective January 1st 2016, to serve as its Chief Executive Officer. Gustavo has more that 20 years of executive management experience in biologics manufacturing and development. Gustavo joined the company as head of the Seattle ...


CHMP grants accelerated assessment for Daratumumab for double refractory multiple myeloma


Genmab A/S announced that the Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMA) has granted accelerated assessment to the Marketing Authorization Application (MAA) for daratumumab.The MAA is for daratumumab as a treatment for patients with relapsed and ...


Ascendis Pharma Announces Positive Top-line Results from a Phase 2 Pediatric Study for the Treatment of Growth Hormone Deficiency


Ascendis Pharma A/S announced positive top-line results from a six-month Phase 2 study to evaluate the safety and efficacy of once-weekly TransCon Growth Hormone in 53 treatment-naïve, pre-pubertal children with growth hormone deficiency, or GHD."We are extremely pleased with the top-line results ...


Genes determine our thirst for coffee

Coffee not associated with lifestyle diseases


We love coffee - and we drink a lot of it. New research from the University of Copenhagen and Herlev and Gentofte Hospital shows that coffee neither increases nor decreases the risk of developing lifestyle diseases such as obesity and diabetes. The researchers have based their study on genes, as ...


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