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Antibiotic Armageddon in UK and Europe by 2025

ESCMID warns that Europe may surpass one million deaths due to ineffective antibiotics by 2025


The European Society of Clinical Microbiology and Infectious Disease (ESCMID) – an organization that explores risk assessment, knowledge sharing and best practices in the fight against infectious disease – has warned that Britain and Europe collectively could face more than a million deaths in an ...


Vaccine against Placental Malaria is ready to start human tests


ExpreS2ion Biotechnologies announced the release by its partners at University of Copenhagen, of a vaccine candidate against the form of malaria that strikes pregnant women, for testing in humans. The vaccine candidate contains a malaria antigen made with ExpreS2ion’s proprietary protein ...


Genmab Acquires Antibody Assets from iDD Biotech


Genmab A/S announced that its subsidiary Genmab Holding B.V. entered into an agreement to purchase antibodies and related patents and know-how from iDD Biotech SAS. The pre-clinical stage antibodies are directed to DR5, also known as Trail Receptor 2 (TRAIL-R2), an emerging cancer target. ...


Recipharm appoints new position of Vice President Quality Management


Recipharm announced that it has appointed Thomas Beck to the new senior role of Vice President Quality Management (VP QM) with effect from 1st April 2015. Thomas is currently Head of Quality Control and Assurance at Recipharm Stockholm, a position that he has held since 2010. He is also Chairman ...


Genmab Enters Commercial DuoBody Technology Agreement with BioNovion in the Field of Immuno-Oncology


Genmab A/S announced it has entered a co-development and commercialization agreement with BioNovion to evaluate a number of DuoBody product candidates targeting immune checkpoints. Genmab and BioNovion will contribute panels of antibodies for the creation of bispecific antibody products using ...


Genmab Announces Preliminary Results in Phase II Study of Daratumumab in Double Refractory Multiple Myeloma


Genmab A/S announced preliminary results from the Phase II study of daratumumab in double refractory multiple myeloma conducted by its collaboration partner Janssen Biotech, Inc. (Janssen). The overall response rate (ORR) in the study was 29.2% in the 16 mg/kg dosing group and the median ...


Ascendis Pharma A/S Announces Initiation of a Phase 1 Single Ascending Dose Study of TransCon Treprostinil


Ascendis Pharma A/S announced that it has initiated a Phase 1 single ascending dose study of TransCon Treprostinil in healthy volunteers. TransCon Treprostinil is being developed to treat pulmonary arterial hypertension, a life-threatening orphan disease characterized by elevated blood pressure ...


CMC Biologics and OncoSynergy Enter into an Agreement for Accelerated Process Development of an Investigational Drug to Combat Ebola

Experimental monoclonal antibody to be used in clinical trials with patients in West Africa infected with the Ebola virus


CMC Biologics and OncoSynergy have entered into an agreement for process development and GMP manufacture of OS2966 – a novel potential treatment for Ebola. The investigational drug candidate, designed to inhibit a major cellular adhesion receptor (CD29) that is fundamental for progression of ...


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Fat cells reprogrammed to increase fat burning


White adipose tissue stores excess calories as fat that can be released for use in other organs during fasting. Mammals also have small amounts of brown adipose tissue, which primarily acts as an effective fat burner for the production of heat. Now researchers from the University of Southern ...


Genmab Announces Phase II Study of Daratumumab in Non-Hodgkin’s Lymphomas


Genmab A/S announced that its collaboration partner, Janssen Biotech, Inc. (Janssen) plans to start a Phase II study of daratumumab in non-Hodgkin’s lymphomas (NHL). The study (LYM2001) will evaluate daratumumab monotherapy in three different types of NHL, diffuse large B-cell lymphoma (DLBCL), ...


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