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Genmab Enters Commercial DuoBody Technology Agreement with BioNovion in the Field of Immuno-Oncology


Genmab A/S announced it has entered a co-development and commercialization agreement with BioNovion to evaluate a number of DuoBody product candidates targeting immune checkpoints. Genmab and BioNovion will contribute panels of antibodies for the creation of bispecific antibody products using ...


Genmab Announces Preliminary Results in Phase II Study of Daratumumab in Double Refractory Multiple Myeloma


Genmab A/S announced preliminary results from the Phase II study of daratumumab in double refractory multiple myeloma conducted by its collaboration partner Janssen Biotech, Inc. (Janssen). The overall response rate (ORR) in the study was 29.2% in the 16 mg/kg dosing group and the median ...


Ascendis Pharma A/S Announces Initiation of a Phase 1 Single Ascending Dose Study of TransCon Treprostinil


Ascendis Pharma A/S announced that it has initiated a Phase 1 single ascending dose study of TransCon Treprostinil in healthy volunteers. TransCon Treprostinil is being developed to treat pulmonary arterial hypertension, a life-threatening orphan disease characterized by elevated blood pressure ...


CMC Biologics and OncoSynergy Enter into an Agreement for Accelerated Process Development of an Investigational Drug to Combat Ebola

Experimental monoclonal antibody to be used in clinical trials with patients in West Africa infected with the Ebola virus


CMC Biologics and OncoSynergy have entered into an agreement for process development and GMP manufacture of OS2966 – a novel potential treatment for Ebola. The investigational drug candidate, designed to inhibit a major cellular adhesion receptor (CD29) that is fundamental for progression of ...


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Fat cells reprogrammed to increase fat burning


White adipose tissue stores excess calories as fat that can be released for use in other organs during fasting. Mammals also have small amounts of brown adipose tissue, which primarily acts as an effective fat burner for the production of heat. Now researchers from the University of Southern ...


Genmab Announces Phase II Study of Daratumumab in Non-Hodgkin’s Lymphomas


Genmab A/S announced that its collaboration partner, Janssen Biotech, Inc. (Janssen) plans to start a Phase II study of daratumumab in non-Hodgkin’s lymphomas (NHL). The study (LYM2001) will evaluate daratumumab monotherapy in three different types of NHL, diffuse large B-cell lymphoma (DLBCL), ...


New enzyme technology converts waste oils into biodiesel


Novozymes announced the launch of Novozymes Eversa®, the first commercially available enzymatic solution to make biodiesel from waste oils. The enzymatic process converts used cooking oil or other lower grade oils into biodiesel. Biodiesel producers can thereby reduce their raw material costs. ...


Contera Pharma announces acquisition by Korean Bukwang Pharmaceutical

JM-010 to enter global development for L-DOPA induced dyskinesia


Contera Pharma announced that Bukwang Pharmaceutical has acquired 100% of Contera Pharma from its current shareholders. The shareholders received an undisclosed upfront payment and are entitled to future contingent and royalty payments. Contera Pharma was founded by John Bondo Hansen and Mikael ...


New guide to the genetic jungle of muscles can help health research


New guide to the genetic jungle of muscles can help health research Researchers from Aarhus University and Bispebjerg Hospital have created a comprehensive overview of how tens of thousands of genes interact in relation to the behavior of muscles. At the same time, they have developed a guide to ...


Genmab Announces New Phase III Combination Study of Daratumumab in Frontline Multiple Myeloma


Genmab A/S announced that the French Intergroup of Myeloma (IFM) in collaboration with Dutch-Belgian Cooperative Trial Group for Hematology Oncology (HOVON) and Janssen Biotech, Inc. (Janssen) plans to start an additional Phase III study of daratumumab in frontline multiple myeloma. The study ...


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