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Tamiflu-resistant influenza

Parsing the genome for the culprits

02-04-2014

EPFL scientists have developed a tool that reveals the mutations that make influenza resistant to Tamiflu, and they have identified new mutations that may render ineffective one of the few treatments currently available on the market. Tamiflu is one of the few available treatments for those who ...

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How brain tumors develop from stem cells

25-03-2014

What causes cancer? This is still one of the most burning questions today. Cancer stem cells are increasingly to be found in the spotlight of research. Researchers from the Biozentrum of the University of Basel and the Austrian Academy of Sciences have found that the loss of function of a protein ...

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Unfolded proteins collapse when exposed to heat

25-03-2014

Not only folded proteins fulfil important functions in the human body; unfolded or intrinsically disordered proteins (IDPs) likewise assume major tasks. Researchers at the University of Zurich have observed how molecular forces influence protein structure. The unfolded proteins become smaller ...

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A tailor made molecule against malaria

A team at the University of Geneva, Switzerland, discovers the Achilles heel of the Plasmodium and aims a molecular arrow to destroy it

13-03-2014

The malaria parasite is particularly pernicious since it is built to develop resistance to treatments. The lack of new therapeutic approaches also contributes to the persistence of this global scourge. A study led by Didier Picard, professor at the Faculty of Sciences of the University of Geneva ...

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Bioengineered growth factors lead to better wound healing

24-02-2014

When we are wounded, our bodies naturally begin a process of repair of the damaged tissue. This process is mediated by biological molecules called growth factors, which are proteins that occur naturally in our cells and guide processes ranging from embryonic development to healing. Given their ...

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How memory and schizophrenia are connected

18-02-2014

Many psychiatric disorders are accompanied by memory deficits. Basel scientists have now identified a network of genes that controls fundamental properties of neurons and is important for human brain activity, memory and the development of schizophrenia. Their results have been published in the ...

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Cc to the brain: how neurons control fine motor behavior of the arm

05-02-2014

Motor commands issued by the brain to activate arm muscles take two different routes. As the research group led by Professor Silvia Arber at the University of Basel's Biozentrum and the Friedrich Miescher Institute for Biomedical Research has now discovered, many neurons in the spinal cord send ...

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Impaired cell division leads to neuronal disorder

03-02-2014

Prof. Erich Nigg and his research group at the Biozentrum of the University of Basel have discovered an amino acid signal essential for error-free cell division. This signal regulates the number of centrosomes in the cell, and its absence results in the development of pathologically altered ...

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New operating principle of potassium channels discovered

30-01-2014

Neurons transmit information with the help of special channels that allow the passage of potassium ions. Defective potassium channels play a role in epilepsy and depression. The scientists working with Prof. Henning Stahlberg at the Biozentrum of the University of Basel have now identified the ...

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Typhoid fever – A race against time

22-01-2014

The life-threatening disease typhoid fever results from the ongoing battle between the bacterial pathogen Salmonella and the immune cells of the body. Prof. Dirk Bumann’s research group at the Biozentrum of the University of Basel has now uncovered how the typhoid pathogen repeatedly manages to ...

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