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Actelion delivers strong half year operational and financial results


Actelion Ltd announced its results for the first half of 2014: Product sales of CHF 993 million, up 17% at Constant Exchange Rates (CER),11% excluding US rebate reversals Core earnings of CHF 421 million, up 35% at CER, 21% excluding US rebate reversals Core EPS of CHF 3.25, an increase of 48% ...


Crenezumab Phase II cognition data in Alzheimer’s disease presented


AC Immune announced the presentation of data from two phase II studies investigating whether crenezumab (anti beta-amyloid antibody) can delay cognitive and functional decline in people with mild-to-moderate Alzheimer’s disease (AD) by its partner Genentech, a member of the Roche Group. The ...


Santhera Repositions Omigapil in Congenital Muscular Dystrophy


Santhera Pharmaceuticals announced the initiation of a clinical program with omigapil, a drug candidate in-licensed from Novartis and repositioned for therapeutic use in Congenital Muscular Dystrophy (CMD). The clinical development program will be initiated with a Phase I study in pediatric CMD ...


Novartis to license Google "smart lens" technology


Novartis announced that its eye care division Alcon has entered into an agreement with a division of Google Inc. to in-license its "smart lens" technology for all ocular medical uses. The agreement with Google[x], a team within Google that is devoted to finding new solutions to big global ...


GlycoVaxyn initiates Phase I clinical trial for vaccine against Extra-intestinal pathogenic Escherichia coli


GlycoVaxyn AG announced the initiation of a Phase 1 clinical trial of a candidate vaccine to prevent infections caused by Extra-intestinal Pathogenic Escherichia coli (ExPEC), such as urinary tract infections (UTIs). The investigational vaccine is being co-developed by GlycoVaxyn AG and Janssen ...


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Nanoscale Velcro used for Molecule Transport


Biological membranes are like a guarded border. They separate the cell from the environment and at the same time control the import and export of molecules. The nuclear membrane can be crossed via many tiny pores. Scientists at the Biozentrum and the Swiss Nanoscience Institute at the University ...


Invisibility cloak for immune cells


The human immune system is very complex. A large number of different cells with various functions ensure that invading microorganisms such as viruses or bacteria can quickly be rendered innocuous and the entire organism stays healthy. The immune system also includes natural killer cells (NK ...


AmVac Initiates Phase III Trial for the Treatment of Bacterial Vaginosis


AmVac AG announced the initiation of a Phase III study with AmVac’s lead vaccine Gynevac in Bacterial Vaginosis (BV). The trial aims to confirm the safety and efficacy of a new generation of the vaccine produced in accordance to the current GMP standards. The previous version, containing ...


Selexipag meets primary endpoint in pivotal Phase III GRIPHON outcome study


Actelion Ltd announced the top-line results of the pivotal Phase III GRIPHON study in 1,156 patients with pulmonary arterial hypertension (PAH) with selexipag, the first selective oral prostacyclin IP receptor agonist. Initial analysis shows that the event-driven outcome study has met its primary ...


Lonza Invests in Single-Use Technology and Facility Upgrades for Clinical Antibody Drug Conjugate Manufacturing


Lonza announced investment plans for technology and facility improvements to its Antibody Drug Conjugate (ADC) clinical manufacturing facility in Visp, Switzerland. The planned upgrades include the introduction of single-use technology for flexible ADC manufacturing, along with a recently ...


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