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Blueprint for blood vessel fusion discovered
12-06-2013
The fusion of blood vessels during the formation of the vascular system follows a uniform process. In this process, the blood vessels involved go through different phases of a common choreography, in which the splitting and the rearrangement of endothelial cells play a critical role. Markus ...
Researchers discover master regulator in cancer metastasis
12-06-2013
In the process of metastasis, the movement of cancer cells to different parts of the body, a specific master regulator gene plays a central role: a transcription factor named Sox4 activates a sequence of genes and triggers the formidable process. This finding is reported by researchers from ...
Swiss-Japanese research suggests origins of key cells in the thymus
31-05-2013
Medullary thymic epithelial cells (mTECs) allow the thymus to ensure that the body’s T cells are able to distinguish between potentially harmful foreign antigens and those that are produced by the body itself. A Swiss-Japanese research team suggests that mTECs do not share a common progenitor ...
Scientists discover the origin of a giant synapse
28-05-2013
Humans and most mammals can determine the spatial origin of sounds with remarkable acuity. We use this ability all the time -- crossing the street; locating an invisible ringing cell phone in a cluttered bedroom. To accomplish this small daily miracle, the brain has developed a circuit that's ...
Proteome atlas for the tuberculosis pathogen
17-05-2013
Photographers know the problem all too well: with the naked eye, you can see which branch a bird is sitting on, but spotting the bird in the blur of branches through the telephoto lens for high-magnification images requires considerable skill. It is a similar story for researchers who are ...
Conversion from bad fat to good fat
30-04-2013
Scientists from ETH Zurich have shown for the first time that brown and white fat cells in a living organism can be converted from one cell type to the other. Their work, using mice as a model organism, provides important new insights into the origin of brown fat cells, which is a ...
Uncleaned cells mean weak muscles
24-04-2013
The protein complex mTORC1 promotes muscle growth. However, should this complex remain constantly active, it impairs the ability of the cells to self-clean, causing myopathy. Scientists working with Markus Rüegg, Professor at the Biozentrum, University of Basel. Similarly to parts in a ...
Highly endowed research project for developing an artificial sphincter
19-04-2013
The lack of control over one’s own bowel movements can severely affect an individual’s quality of life. Researchers at the University of Basel want to develop an adaptive implant that would be able to contract and relax like a natural muscle. The national research initiative Nano-Tera.ch will ...
Wild mice have natural protection against Lyme borreliosis
05-04-2013
Like humans, mice can become infected with Borrelia. However, not all mice that come into contact with these bacteria contract the dreaded Lyme disease: Animals with a particular gene variant are immune to the bacteria, as scientists from the universities of Zurich and Lund demonstrate. Wild ...
Selectively manipulating protein modifications
12-03-2013
Protein activity is strictly regulated. Incorrect or poor protein regulation can lead to uncontrolled growth and thus cancer or chronic inflammation. Members of the Institute of Veterinary Biochemistry and Molecular Biology from the University of Zurich have identified enzymes that can ...
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