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Hybrid material for controlled drug delivery

16-04-2013

A ladder-like aminopropylsilsesquioxane that could be used as a drug delivery system for ibuprofen has been synthesised by scientists in France. The work demonstrates how it is possible to control drug delivery through the design and synthesis of a hybrid material. Drug release tests using ...

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The adult generations of today are less healthy than their counterparts of previous generations

Results from a large cohort study suggest that exposure to metabolic risks of cardiovascular disease is increasing

11-04-2013

Despite their greater life expectancy, the adults of today are less "metabolically" healthy than their counterparts of previous generations. That's the conclusion of a large cohort study from the Netherlands which compared generational shifts in a range of well established metabolic risk ...

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Social bees mark dangerous flowers with chemical signals

18-03-2013

Scientists already knew that some social bee species warn their conspecifics when detecting the presence of a predator near their hive, which in turn causes an attack response to the possible predator. Researchers at the University of Tours in collaboration with the Experimental Station of ...

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Trophos announces positive interim review in pivotal study of olesoxime in Spinal Muscular Atrophy

04-03-2013

Trophos SA announced the completion of the interim analysis of the pivotal efficacy study of olesoxime in the rare neurodegenerative condition Spinal Muscular Atrophy (SMA).The independent Data Monitoring Committee (DMC) has reviewed the treatment effect at one year on the primary outcome ...

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Quinten identifies a combination of two synergistic markers that predicts a favorable response to treatment in breast cancer

27-02-2013

Quinten announced the identification of two discriminating biological marker candidates which are indicative of a favorable response to treatment in women suffering from triple-negative breast cancer (TNBC). In the sub-group with both markers in combination, 86 per cent of women responded to ...

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Provence Technologies launches new USD 1.7 million research programme

Screening 1000, the research project conducted by Provence Technologies, is set up to find and market a new ultra-pure molecule

30-01-2013

Provence Technologies announces the launch of Screening 1000, a new USD 1.7 million (EUR 1.3 million) research programme with the goal of discovering a new ultra-pure molecule for the healthcare market. The project is being launched by the R&D department of Provence Technologies and is being ...

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Domain Therapeutics grants Prexton Therapeutics an exclusive option to license and develop mGluR4 PAMs for Parkinson’s disease

29-01-2013

Domain Therapeutics S.A. announced that Domain Therapeutics grants Prexton Therapeutics an exclusive option to license and develop metabotropic glutamate receptor 4 (mGluR4) Positive Allosteric Modulator (PAM) drugs targeting Parkinson’s disease. This agreement between Domain Therapeutics and ...

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Genetic admixture in southern Africa

Ancient Khoisan lineages survive in contemporary Bantu groups

21-01-2013

An international team of researchers from the MPI for Evolutionary Anthropology in Leipzig and the CNRS in Lyon have investigated the maternally inherited mitochondrial DNA of 500 individuals from southern Africa speaking different Khoisan and Bantu languages. Their results demonstrate that ...

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NovAliX enters into fragment-based drug discovery alliance with Kyowa Hakko Kirin

17-01-2013

NovAliX SAS announced that it has entered into a fragment-based drug discovery alliance with Kyowa Hakko Kirin Co., Ltd., Japan. Within the alliance, the companies will collaborate to develop novel drug candidates against protein-protein interaction targets. Under the terms of the agreement ...

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Newly discovered organisms to help clean up nuclear waste

15-01-2013

The nuclear industry generates radioactive toxic waste, which needs to be decontaminated inside the facilities themselves and of the effluents released into the environment. Radionuclide decontamination is currently performed using physico-chemical methods and while they work well, they are ...

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