World's first protective antibodies against Marburg virus developed
"We are happy, that we could contribute to the worldwide first recombinant protective antibodies against Marburg virus using our antibody phage display technology. We hope, that these antibodies will be developed as therapeutic in the future“, says project leader Prof. Dr. Michael Hust from the Institute of Biochemistry, Biotechnology and Bioinformatics of the TU Braunschweig. Dr. Sebastian Miethe adds: “The development of these antibodies was only possible in close cooperation with our partners in France and USA. These long lasting cooperation was also successful in other projects focused on pathogens and toxins.“
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Jeffrey W. Froude, Thibaut Pelat, Sebastian Miethe, Samantha E. Zak, Anna Z. Wec, Kartik Chandran, Jennifer Mary Brannan, Russell R. Bakken, Michael Hust, Philippe Thullier & John M. Dye; "Generation and characterization of protective antibodies to Marburg virus"; mAbs; 2017
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Topic world Antibodies
Antibodies are specialized molecules of our immune system that can specifically recognize and neutralize pathogens or foreign substances. Antibody research in biotech and pharma has recognized this natural defense potential and is working intensively to make it therapeutically useful. From monoclonal antibodies used against cancer or autoimmune diseases to antibody-drug conjugates that specifically transport drugs to disease cells - the possibilities are enormous
Topic world Antibodies
Antibodies are specialized molecules of our immune system that can specifically recognize and neutralize pathogens or foreign substances. Antibody research in biotech and pharma has recognized this natural defense potential and is working intensively to make it therapeutically useful. From monoclonal antibodies used against cancer or autoimmune diseases to antibody-drug conjugates that specifically transport drugs to disease cells - the possibilities are enormous