28-06-2011: Adocia SAS announced the launch of its second clinical trial for the development of HinsBet(R), its fast-acting human insulin.
The company completed a Phase I study in March on healthy volunteers showing that the action of HinsBet(R) is as fast as that of NovoLog(R) and has less variability. The positive clinical results obtained with HinsBet(R) during the Phase I study have permitted to quickly start a second study of Phase IIa on 20 type 1 diabetics.
The Phase IIa study is double-blinded, under euglycemic clamp, and aims to compare variabilities of HinsBet(R) and NovoLog(R) with three repeated injections of each product to each patient.
“We expect this study to confirm HinsBet(R)’s similar efficacy on type 1 diabetics compared with Novo Nordisk’s fast-acting insulin analog which is the market leader,” said Dr Gérard Soula, president and CEO at Adocia.
Adocia has developed HinsBet(R) using its BioChaperone(R) library of polysaccharides modified with naturally occurring molecules. BioChaperone(R) is designed to form a reversible molecular complex with therapeutic proteins in order to solubilize and stabilize these proteins and to control their delivery.
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Adocia SAS announced the launch of its second clinical trial for the development of HinsBet(R), its fast-acting human insulin.The company completed a Phase I study in March on healthy volunteers showing that the action of HinsBet(R) is as fast as that of NovoLog(R) and has less variability. ... more