Neurodegenerative Disorders

News Neurodegenerative Disorders

• Control of cellular recycling pathways
  

  Together with researchers from the University of Rome/Italy and the Italian National Institute for Infectious Diseases scientists from the Freiburg Institute for Advanced Studies (FRIAS) and the Center for Biological Systems Analysis (ZBSA) shed light onto the highly organized and complicated regula more

• Merck Serono Announces Creation of First Spin-Off Company From Its Entrepreneur Partnership Program

  Merck Serono, a division of Merck, Darmstadt, Germany, announced the creation of Prexton Therapeutics, the first spin-off company resulting from its Entrepreneur Partnership Program launched in April 2012. Prexton Therapeutics will be formed around Merck Serono’s R&D portfolio in the field of Parkin more

• New Brain Protein
  

  A protein essential for metabolism and recently associated with neurodegenerative diseases also occurs in several brain-specific forms. This discovery emerged in the course of a research project funded by the Austrian Science Fund FWF, the findings of which have now been published in the journal Hum more

Publications Neurodegenerative Disorders

• The 3′ UTR of FMR1 mRNA is a target of miR-101, miR-129-5p and miR-221: implications for the molecular pathology of FXTAS at the synapse

  While FMR1 is silenced in Fragile X syndrome (FXS) patients carrying the full mutation, its expression is elevated (2–8 fold) in premutated individuals. These people may develop the Fragile X-associated Tremor/Ataxia syndrome (FXTAS), a late onset neurodegenerative disorder characterized by ataxia more

• β‐Phenethylamine—A Phenylalanine Derivative in Brain—Contributes to Oxidative Stress by Inhibiting Mitochondrial Complexes and DT‐Diaphorase: An In Silico Study

  Summary Aim Till date, the mode of action of β‐PEA on neurons is not well illustrated. We tested the hypothesis that β–PEA has the ability to cause oxidative stress by inhibiting the antioxidant enzyme DT‐diaphorase and mitochondrial complexes (Complex‐I and complex‐III). Methods Using more

• Rho Kinase Inhibitor Fasudil Protects against β‐Amyloid‐Induced Hippocampal Neurodegeneration in Rats

  Summary Background and purpose Alzheimer's disease (AD) is a progressive neurodegenerative disorder, and Aβ‐induced neuronal damage is the major pathology of AD. There is increasing evidence that neuroinflammation induced by Aβ is also involved in the pathogenesis of AD. Fasudil is a Rho kinas more

Market studies Neurodegenerative Disorders

• Genfit (ALGFT) - Financial and Strategic SWOT Analysis Review

  Genfit (Genfit) is a publicly held biopharmaceutical company specialized in developing medicines for the early prevention and treatment of cardiometabolic diseases and related disorders. The company has its research work concentrated on the discovery and development of new treatments for the growing more

• Rexahn Pharmaceuticals, Inc. (RNN) - Financial and Strategic SWOT Analysis Review

  Rexahn Pharmaceuticals, Inc., (Rexahn Pharmaceuticals) is a biopharmaceutical company that is engaged in the discovery, manufacture and development of treatments for central nervous system (CNS) disorders, cancer and sexual dysfunction. It has developed three clinical stage drug candidates namely Se more

• Proximagen Group plc (PRX) - Financial and Strategic SWOT Analysis Review

  Proximagen Group plc, formerly known as Proximagen Neuroscience plc, is a publicly traded neuroscience research company, engaged in developing drugs for the treatment of neurodegenerative disorders. It principally focuses on parkinson's disease, epilepsy, gognition, oncology, inflammation and neuroi more

Websites Neurodegenerative Disorders