Milestones

News Milestones

• NovAliX enters into fragment-based drug discovery alliance with Kyowa Hakko Kirin

  NovAliX SAS announced that it has entered into a fragment-based drug discovery alliance with Kyowa Hakko Kirin Co., Ltd., Japan. Within the alliance, the companies will collaborate to develop novel drug candidates against protein-protein interaction targets. Under the terms of the agreement NovAliX more

• Evolva reaches first milestone in Roquette collaboration

  Evolva Holding SA announced that Roquette Frères SA (Roquette) has confirmed that Evolva has achieved the first milestone in their collaboration that was announced in January 2012. The ultimate objective of the collaboration is the development of novel and optimised biosynthetic production routes fo more

• Photocure announces the achievement of the second transition milestone of EUR 1.5 million for Hexvix

  Photocure ASA announced the achievement of the second manufacturing transition milestone from Ipsen, its new strategic partner for commercializing Hexvix worldwide, excluding the US and Nordic region. This triggers a payment of EUR 1.5 million. Hexvix is Photocure’s flagship product to aid in diagno more

White papers Milestones

• High sensitive detection of follistatin by Imperacer®: an initial study on the way to analytical gene-doping tests
  

  For the understanding of interactions in the muscle-growth directing myostatin-pathway and therefore also for the establishment of high sensitive detection strategies for gene-doping, detailed studies of protein concentration levels in biological matrices and appropriate highly sensitive analytic techniques for quantitative monitoring of these biomarkers are required. In this work, the development of a high sensitive assay for follistatin based on the Imperacer® technology is described. The quantification limit in human serum was found at 60 pg/ml in only 6 µl sample volume. With this initial assay we demonstrate the first application in a set of analytical tests for a high sensitive myostatin pathway related profiling. more

• Half a Century of Chromatography with Agilent and Predecessors
  

  Twsett originated the chromatography with his work about the separation of chlorophyll in 1903. For some time it was relatively quite around this new technology. Exceptions were the workings of Kuhn and Lederer (1931) as well as of Hesse (1936 and 1942). A break through succeeded to E. Cremer during the 40ies, but hardly considered caused by the war events, what however in the years 1950/51 by the conception of the gas chromatography suddenly changed and involved a rapid development more

Publications Milestones

• 109 kb Deletion of Chromosome 4p16.3 in a Patient With Mild Phenotype of Wolf–Hirschhorn Syndrome

  Abstract Wolf–Hirschhorn syndrome (WHS) is a contiguous gene deletion syndrome associated with growth retardation, developmental disabilities, epileptic seizures, and distinct facial features resulting from a deletion of the short arm of chromosome 4. The Wolf–Hirschhorn Syndrome Critical Regio more

• A Newly Recognized Autosomal Recessive Syndrome Affecting Neurologic Function and Vision

  Abstract Genetic factors represent an important etiologic group in the causation of intellectual disability. We describe a Saudi Arabian family with closley related parents in which four of six children were affected by a congenital cognitive disturbance. The four individuals (aged 18, 16, 13, more

• Using AI to Understand Key Success Features in Evolving CTSAs

  Abstract A vital role for Clinical and Translational Science Award (CTSA) evaluators is to first identify and then articulate the necessary change processes that support the research infrastructures and achieve synergies needed to improve health through research. The use of qualitative evaluatio more

Market studies Milestones

• XOMA Corporation – Product Pipeline Review – 2012

  Introduction Global Market Direct’s pharmaceuticals report, “XOMA Corporation - Product Pipeline Review - 2012” provides data on the XOMA Corporation’s research and development focus. The report includes information on current developmental pipeline, complete with latest updates, and features on d more

• Orexo AB – Product Pipeline Review – 2012

  Introduction Global Market Direct’s pharmaceuticals report, “Orexo AB - Product Pipeline Review - 2012” provides data on the Orexo AB’s research and development focus. The report includes information on current developmental pipeline, complete with latest updates, and features on discontinued and more

• Paladin Labs Inc. – Product Pipeline Review – 2012

  Introduction Global Market Direct’s pharmaceuticals report, “Paladin Labs Inc. - Product Pipeline Review - 2012” provides data on the Paladin Labs Inc.’s research and development focus. The report includes information on current developmental pipeline, complete with latest updates, and features on more

Websites Milestones