Micro-Arrays

Companies Microarrays

Eppendorf AG, Germany

Eppendorf is a leading life science company that develops and sells instruments, consumables, and services for liquid-, sample-, and cell handling in laboratories worldwide. Its product range includes pipettes and automated pipetting systems, dispensers, centrifuges, mixers, spectrometers, and DNA a more

Miltenyi Biotec GmbH, Germany

Miltenyi Biotec is a global provider of products and services that advance biomedical research and cellular therapy. Since 1989, we have developed innovative and reliable technologies for scientists and clinicians around the world. Our integrated portfolio of tools covers techniques of sample prepar more

dichrom GmbH, Germany

dichrom - formerly SeQuant GmbH – is concentrating on the distribution and support of high quality products for liquid chromatography synthesis and isolation. The personal and individual customer support is of substantial importance for dichrom. Here a competent and comprehensive product and applica more

Products Microarrays

Protagen AG: Your reliable partner for biotherapeutical development

UNIchip® allows faster and more efficient selection of monoclonal antibodies and high affinity biotherapeutic reagents with improved specifity and stability in the development phase. more

Services Microarrays

A world of flexibility: BIOS ANALYTIQUE Rental Solutions

Get the instrument you need without waiting for an investment budget! From 1 to 60 months, from one module to a complete system, whether to react on more

News Microarrays

• AyoxxA Biosystems Closes Series A Financing Round

  AyoxxA Biosystems announced it has closed a 2.6 million Euro Series A financing round. The round was led by Wellington Partners Venture Capital and included NRW.BANK, HTGF – High-Tech-Gründerfonds, and private investors, Rainer Christine and Dr. Gregor Siebenkotten, both formerly executive board mem more

• VTT speeds up drug development with more advanced microarray technology

  RNA interference technology, which is used in cell biology, has revolutionised functional research of the gene products in the last ten years. VTT Technical Research Centre of Finland has developed a method which allows a single microchip to be used to screen the functions of tens of thousands of ge more

• PEPperPRINT wins 30th German Industry’s Innovation Award

  PEPperPRINT has won German Industry’s Innovation Award 2010 in the startup category. The biotech company from Heidelberg, Germany, was awarded in line of 30th German Industry’s Gala at the Congress Center Frankfurt by Federal Minister of Education and Research, Dr. Annette Schavan. PEPperPRINT w more

White papers Microarrays

• Acquired Copy Number Alterations in Adult Acute Myeloid Leukemia Genomes
  

  To complement cytogenetic studies and to identify genes altered in AML genomes, Walter and co-workers performed a genome-wide copy number analysis with paired normal and tumor DNA obtained from 86 adult subjects with de novo AML using 1.85 million feature SNP arrays. A total of 201 somatic CNAs were found in the 86 AML genomes (mean, 2.34 CNAs per genome), with FAB-System M6 and M7 genomes containing the most changes (10-29 CNAs per genome). According to the authors' conclusions, the use of an unbiased high-resolution genomic screen identified many genes not previously implicated in AML that may be relevant for pathogenesis, along with many known oncogenes and tumor suppressor genes. Despite the ability of next-generation sequencing platforms to accurately identify amplifications, deletions, and translocations, a multiplatform approach (traditional cytogenetics, FISH, SNP array, array CGH, and targeted gene resequencing) will continue to be the most practical approach to studying AML genomes at most institut more

• HelpCorner - Transfection
  

  Transfection is the delivery of DNA, RNA, proteins, and macromelecules into eukaryotic cells. The goals for transfection include the study of gene function and regulation as well as protein expression and function. It is also used for gene silencing and protein production. According to the application, the information can be either transiently (transient transfection) or permanently expressed (stable transfection). Based on the strategies, the transfection methods can be divided into three groups: more

• Adaptation of SmartAmp-2 Assays for Microsatellite Copy Number Polymorphism Detection on the LightCycler® 480 Instrument
  

  The Smart Amplification process, version 2 (SMAP-2), also known as SmartAmp-2, is a rapid polymorphism detection system based on a unique asymmetric primer design, including a folding primer (FP) and a turn-back primer (TP) [1]. Combined with Thermus aquaticus MutS (Taq MutS) protein in an isothermal amplification procedure, the technique enables suppression of mis-amplification of highly related sequences (e.g., a wild-type sequence versus an SNP variant), minimizing background amplification. The Taq MutS protein binds to mis-matched nucleotides in erroneously primed dsDNA and prevents further amplification by blocking the dissociation of DNA duplexes having a mis-match by DNA polymerases having strand displacement activity. SmartAmp-2 assays have been used for detection of various SNPs and mutations, e.g., in ALDH2 and EGFR genes [1,2]. In the study presented here, we investigated whether this assay principle could be adapted for detection of microsatellite polymorphisms showing copy number differences in more

Publications Microarrays

• Using multivariate methods to infer knowledge from genomic data

  Using multivariate methods to infer knowledge from genomic dataLiliana López-Kleine; Nicolás Molano; Luis OspinaInternational Journal of Bioinformatics Research and Applications, Vol. 9, No. 3 (2013) pp. 285 - 300Since the introduction of genome sequencing techniques several methods for genomic d more

• A temporal switch model for estimating transcriptional activity in gene expression

  Motivation: The analysis and mechanistic modelling of time series gene expression data provided by techniques such as microarrays, NanoString, reverse transcription–polymerase chain reaction and advanced sequencing are invaluable for developing an understanding of the variation in key biological pr more

• Subpathway-GM: identification of metabolic subpathways via joint power of interesting genes and metabolites and their topologies within pathways

  Various ‘omics’ technologies, including microarrays and gas chromatography mass spectrometry, can be used to identify hundreds of interesting genes, proteins and metabolites, such as differential genes, proteins and metabolites associated with diseases. Identifying metabolic pathways has become an more

Market studies Microarrays

• Molecular Diagnostics Markets

  The technologies that constitute molecular diagnostics--like first-generation amplification, DNA probes, fluorescent in situ hybridization (FISH), second-generation biochips and microfluidics, next-generation signal detection, biosensors, and molecular labels--are influencing the discovery of therap more

• Kreatech Holding B.V. - Strategic SWOT Analysis Review

  Kreatech Holding B.V. - Strategic SWOT Analysis Review Summary Kreatech Holding B.V. (Kreatech Diagnostics) is a privately-held molecular diagnostics company. It is engaged in the development, manufacture and marketing of innovative labeling and detection products for applications in diagnostic an more

• BioTex, Inc. - Strategic SWOT Analysis Review

  BioTex, Inc. (BioTex) is engaged in the research, development and marketing of novel optical solutions and technologies for medical, biomedical, and environmental fields. BioTex develops new technologies for glucose sensing, laser therapy, optical diagnostics, microbial identification and microarra more

Websites Microarrays