Medicinal Chemistry

Companies Medicinal Chemistry

News Medicinal Chemistry

• Lead Discovery Center participates in new pan-European drug discovery platform

  The European Lead Factory, a novel platform for innovative drug discovery, was launched early February by an international consortium of 30 partners including the Lead Discovery Center GmbH (LDC). LDC is an expert in the discovery and generation of small molecule lead series by translating basic res more

• Small change for a big improvement – halogen bonds and drug discovery
  

  Halogen bonding has been applied in crystal engineering, materials research, and nanotechnology for some time. Scientists from the Heidelberg Institute for Theoretical Studies (HITS) and the Czech Academy of Science in Prague have now developed a new tool to use halogen bonds for drug discovery appl more

• AMRI Announces Strategic Contract with Knopp Biosciences

  AMRI announced that it has entered into a new strategic agreement with Knopp Biosciences LLC.  Under the two-year term of the FTE agreement, AMRI will provide various discovery-related services that include medicinal chemistry, DMPK and computer-aided drug discovery (CADD). As part of the scope of w more

Publications Medicinal Chemistry

• Inhibitors of BACE for treating Alzheimer's disease: a fragment-based drug discovery story

  Publication date: Available online 14 May 2013 Source:Current Opinion in Chemical Biology Author(s): Andrew Stamford , Corey Strickland Several fragment-based methods have been applied to the discovery of new lead sources for inhibitors of BACE1, an important therapeutic target for Alzheimer more

• Protein conjugation with genetically encoded unnatural amino acids

  Publication date: Available online 9 May 2013 Source:Current Opinion in Chemical Biology Author(s): Chan Hyuk Kim , Jun Y Axup , Peter G Schultz The site-specific incorporation of unnatural amino acids with orthogonal chemical reactivity into proteins enables the synthesis of structurally d more

• Toward engineering efficient peptidomimetics. screening conformational landscape of two modified dehydroaminoacids

  Abstract Effective peptidomimetics should posses structural rigidity and appropriate interaction pattern leading to potential spatial and electronic matching to the target receptor site. Rational design of such small bioactive molecules could push chemical synthesis and molecular modeling toward more

Market studies Medicinal Chemistry

• Critical Outcome Technologies Inc. (COT) - Financial and Strategic SWOT Analysis Review

  Critical Outcome Technologies Inc. (COTI) is a publicly held biotechnology company. It is engaged in the discovery and pre-clinical development of small molecules for the treatment of various human diseases. The company has developed its proprietary platform technology chemsas based on combination o more

• Torrent Pharmaceuticals Limited (500420) - Financial and Strategic SWOT Analysis Review

  Torrent Pharmaceuticals Limited (Torrent) is a public company engaged in the research, development and marketing of active pharmaceutical ingredients (APIs). It is a flagship company of Torrent group. Torrent's research and development (R&D) is focused on breakthrough discoveries in the therapeutic more

• The Changing Role of Natural Products in Drug Discovery

  Introduction This report reveals how natural products have been of value to the pharmaceutical industry and yet how relatively little of their potential has been explored. It assesses strategies for exploring their continued potential and examines the therapeutic areas in which natural products may more

Websites Medicinal Chemistry