Macromolecules

Companies Macromolecules

Postnova Analytics GmbH, Germany

Leading Manufacturer of Systems and Services for Field-Flow Fractionation and Light Scattering used for the Separation and Characterization of Biopolymers, Protein Aggregates and Nanoparticles. Chromatography Supplies and Consumables for GPC, SEC, HPLC and CE. more

News Macromolecules

• A macromolecular shredder for RNA
  

  Much in the same way as we use shredders to destroy documents that are no longer useful or that contain potentially damaging information, cells use molecular machines to degrade unwanted or defective macromolecules. Scientists of the MPI of Biochemistry have now decoded the structure and the operati more

• Biodegradable particles can bypass mucus, release drugs over time

  Johns Hopkins University researchers have created biodegradable nanosized particles that can easily slip through the body's sticky and viscous mucus secretions to deliver a sustained-release medication cargo. The researchers say these nanoparticles, which degrade over time into harmless components, more

• Pairing Nanoparticles with Proteins

  In groundbreaking research, scientists have demonstrated the ability to strategically attach gold nanoparticlesto proteins so as to form sheets of protein-gold arrays. The nanoparticles and methods to create nanoparticle-protein complexes can be used to help decipher protein structures, to identify more

White papers Macromolecules

• Dynamic Light Scattering - an Important Tool for Protein Crystallography and Nanotechnology
  

  Dynamic Light Scattering (DLS) is an established technique in the field of protein crystallography. DLS is used to measure hydrodynamic sizes, polydispersities and aggregation effects of protein samples. These are important parameters for the crystallisation of proteins. DLS is also used in the nanotechnology research for the accurate and fast size measurement of nanoparticles made of different materials. more

• Field-Flow Fractionation - The Universal Separation Principle for Particle and Macromolecule Characterization
  

  High molecular weight polymers, bio molecules or particles in a range of a few nanometers up to several microns are more and more important in science and technology. Many applications are based on the specific properties of these materials. For this reason, an exact knowledge of the molar mass or particle sizes distribution is essential for later application as well as for optimization of the production processes or quality control. In addition the knowledge about the chain structure of macromolecules or biopolymers as well as about the shape of particles is often necessary. For this reason those samples, which often can be very complex systems, have to be separated according to parameters such as e.g. hydrodynamic volume or molecular weight. After the separation process the resulting narrow dispersed fractions are detected with different techniques. more

• Do you see the complete picture?
  

  Gel permeation chromatography (GPC) or also named size exclusion chromatography (SEC) is the most often used method for determining the molecular weight of natural and synthetic macromolecules. One specific strength of this method lies in the fact that by the separation process the whole molecular weight distribution is obtained. The molecular weight distribution contains much larger information for the characterization of polymer samples compared to a single value. more

Publications Macromolecules

• Nanostructural control of the release of macromolecules from silica sol gels

  Publication date: Available online 2 May 2013Source:Acta Biomaterialia Author(s): Shula Radin , Sanjib Bhattacharyya , Paul Ducheyne Therapeutic use of biological molecules such as growth factors and monoclonal antibodies is challenging in view of their limited half-life in vivo. This has eli more

• Effect of Chemical Permeation Enhancers on Stratum Corneum Barrier Lipid Organizational Structure and Interferon Alpha Permeability

  The outermost layer of the skin, known as the stratum corneum (SC), is composed of dead corneocytes embedded in an intercellular lipid matrix consisting of ceramides, free fatty acids, and cholesterol. The high level of organization within this matrix protects the body by limiting the permeation of more

• High NaCl- and urea-induced posttranslational modifications that increase glycerophosphocholine by inhibiting GDPD5 phosphodiesterase [Physiology]

  Glycerophosphocholine (GPC) is high in cells of the renal inner medulla where high interstitial NaCl and urea power concentration of the urine. GPC protects inner medullary cells against the perturbing effects of high NaCl and urea by stabilizing intracellular macromolecules. Degradation of GPC is c more

Market studies Macromolecules

• Atto Corporation - Strategic SWOT Analysis Review

  Atto Corporation (Atto) is a medical device manufacturing company principally engaged in developing, manufacturing and marketing of biological macromolecules and analytical products in the biochemistry, molecular biology and biotechnology fields. The company develops Electrophoresis systems, Chromat more

Websites Macromolecules