Lung Diseases

News Lung Diseases

• First, do no harm: Study finds danger in standard treatment for a serious lung disease
  

  A combination of three drugs used worldwide as the standard of care for a serious lung disease puts patients in danger of death or hospitalization, and should not be used together to treat the disease, called idiopathic pulmonary fibrosis, according to the surprising results of a rigorous independen more

• Statins may increase risk of interstitial lung abnormalities in smokers

  Use of statins may influence susceptibility to or the progression of interstitial lung disease (ILD) in smokers, according to a new study. While some studies have suggested that statins might be beneficial in the treatment of fibrotic lung disease, others have suggested that they may contribute to t more

• Repurposed transplant drug gives hope to women with fatal lung disease

  A drug typically used to prevent organ rejection in transplant patients has been shown to reverse the progress of an often fatal lung disease in women, according to findings published in The New England Journal of Medicine.The discovery marks the first effective therapy scientists have ever found fo more

Publications Lung Diseases

• Steroidogenic enzyme Cyp11a1 regulates Type 2 CD8+ T cell skewing in allergic lung disease [Immunology]

  Allergic asthma is a heterogeneous inflammatory disorder of the airways characterized by chronic airway inflammation and airway hyperresponsiveness. Numbers of CD8+IL-13+ T cells are increased in asthmatics and during the development of experimental asthma in mice. In an atopic environment rich in I more

• Noninvasive Monitoring of Pulmonary Fibrosis by Targeting Matrix Metalloproteinases (MMPs)

  While idiopathic pulmonary fibrosis (PF) is a devastating lung disease, the management of PF including effective monitoring of disease progression remains a challenge. Herein, we introduce a novel, fast, and ultrasensitive metalloproteinase (MMP) activatable optical probe, named MMP-P12, to noninvas more

• The TGFbeta‐BMP Signalling Pathway in pulmonary vascular homeostasis and disease

  Abstract  Germ‐line mutations in the Bone Morphogenetic Protein type II receptor (BMPR2; BMPR‐II) gene, a Transforming Growth Factor beta (TGFβ) receptor superfamily member, cause the majority of heritable pulmonary arterial hypertension (PAH) cases. PAH is a subset of pulmonary hypertension (PH) more

Market studies Lung Diseases

• Lung Disease – Pipeline Review, H2 2012

  Introduction Global Markets Direct’s, 'Lung Disease - Pipeline Review, H2 2012', provides an overview of the indication’s therapeutic pipeline. This report provides information on the therapeutic development for Lung Disease, complete with latest updates, and special features on late-stage and dis more

• Endpoints - Clinical Trials in Respiratory Diseases - Pulmonary Function Tests, Biomarkers and Quality of Life Questionnaires All Play Prominent Roles

  GBI Research in its report “Endpoints - Clinical Trials in Respiratory Diseases - Pulmonary Function Tests, Biomarkers and Quality of Life Questionnaires All Play Prominent Roles” presents the use of endpoints or outcomes measures in respiratory disease’s clinical trials. In this report, endpoint us more

• Circadian Technologies Limited (CIR) - Financial and Strategic SWOT Analysis Review

  Circadian Technologies Limited (Circadian) is a publicly held Australia-based biotechnology company. The company is principally engaged in developing innovative, biologics-based therapies for the treatment of cancer and other serious human illness. Circadian, through its wholly owned subsidiary, Veg more

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