Topic Japan

News Japan

• Japan's Ministry of Health, Labour and Welfare grants approval for Actelion's miglustat for the treatment of Niemann-Pick type C disease

  Actelion Ltd announced that Japan's Ministry of Health, Labour and Welfare has granted approval for miglustat for the treatment of Niemann-Pick type C disease.The approval was based on the data generated for the first approval of miglustat in this indication in the European Union, as well as data sp more

• Plasticell announces grant of fundamental CombiCult patents in USA and Japan

  Plasticell announced that patents for its combinatorial cell culture platform technology, CombiCult™, have been granted in the USA and Japan.  Patents covering CombiCult™ have now been issued in Europe, USA, Japan, Australia and Singapore.“Plasticell's  proprietary technology breaks the major bottle more

• Provepharm signs license agreement with Daiichi Sankyo to provide methylthioninium chloride Proveblue solution for injection to Japan

  Provepharm announced that it has entered into an exclusive licensing agreement with Daiichi Sankyo to make Provepharm’s injectable medicinal product, Methylthioninium chloride Proveblue, available in Japan. The Proveblue medicinal product is used for the treatment of methaemoglobinaemia induced by l more

White papers Japan

• DKSH Performance Materials: Introduction of new program to source products
  

  Even under pressure to reduce costs, effective cooperation and hard work will always find a way to fulfill expectations. Most global players in the pharmaceutical industry are facing dramatic changes: blockbuster products launched in the 1990s will lose their patents over the next few years and face competition which will threaten their steady earnings more

• New Silicone Technologies for Skin Care
  

  In today's competitive skin care market, consumers look for a range of benefits, superior aesthetics and cost effectiveness. In response, formulators strive to create products that are multifunctional, easy to use and effective in small quantities. At the same time, the most successful products deliver benefits that stand out from those of the competition. Creams, lotions and color cosmetics must be easy to spread and comfortable to wear, without feeling tacky or greasy. Silicones have been popular ingredients in skin care products for more than fifty years. These versatile materials are known for their emolliency, wetting and spreading characteristics and ability to provide unique aesthetics. As technology continues to evolve, silicones increasingly offer multifunctional, high performance properties. This article reviews some of the newest silicone technologies available for the formulation of innovative skin care products more

• Adaptation of SmartAmp-2 Assays for Microsatellite Copy Number Polymorphism Detection on the LightCycler® 480 Instrument
  

  The Smart Amplification process, version 2 (SMAP-2), also known as SmartAmp-2, is a rapid polymorphism detection system based on a unique asymmetric primer design, including a folding primer (FP) and a turn-back primer (TP) [1]. Combined with Thermus aquaticus MutS (Taq MutS) protein in an isothermal amplification procedure, the technique enables suppression of mis-amplification of highly related sequences (e.g., a wild-type sequence versus an SNP variant), minimizing background amplification. The Taq MutS protein binds to mis-matched nucleotides in erroneously primed dsDNA and prevents further amplification by blocking the dissociation of DNA duplexes having a mis-match by DNA polymerases having strand displacement activity. SmartAmp-2 assays have been used for detection of various SNPs and mutations, e.g., in ALDH2 and EGFR genes [1,2]. In the study presented here, we investigated whether this assay principle could be adapted for detection of microsatellite polymorphisms showing copy number differences in more

Publications Japan

• No associations found between the genes situated at 6p22.1, HIST1H2BJ, PRSS16, and PGBD1 in Japanese patients diagnosed with schizophrenia

  Abstract Recent GWAS demonstrated an association between candidate genes located at region 6p22.1 and schizophrenia. This region has been reported to house certain candidate SNPs, which may be associated with schizophrenia at HIST1H2BJ, PRSS16, and PGBD1. These genes may presumably be associated more

• Detection of human bocavirus 1 and 2 from children with acute gastroenteritis in Japan

  Abstract This study reports the detection and the genetic characterization of HBoV, a new member in the Parvoviridae family. Among 177 fecal specimens collected from children with diarrhea younger than 5 years in Japan, 11 (6.2%) were positive for HBoV. Co‐infection with other enteric viruses (no more

• Erratum to: Suppressive effects of natural reduced waters on alloxan-induced apoptosis and type 1 diabetes mellitus

  Erratum to: Suppressive effects of natural reduced waters on alloxan-induced apoptosis and type 1 diabetes mellitus Content Type Journal Article Category Erratum Pages 1-1 DOI 10.1007/s10616-012-9461-2 Authors Yuping Li, Department of Bioscience and Biotechnology, Faculty of Agriculture more

Market studies Japan

• Anal Cancer Therapeutics - Pipeline Assessment and Market Forecasts to 2019

  Introduction GlobalData, the industry analysis specialist, has released its new report, “Anal Cancer Therapeutics - Pipeline Assessment and Market Forecasts to 2019”. The report is an essential source of information and analysis on the global Anal Cancer Therapeutics market. The report identifies t more

• Humulin (Type 2 Diabetes) - Analysis and Forecasts to 2020

  Introduction GlobalData’s pharmaceuticals report, “Humulin (Type 2 Diabetes) – Analysis and Forecasts to 2020” provides Humulin sales estimates for US, EU5 and Japan. In addition, it covers detailed clinical assessment of the drug, factors impacting drug sales, competitive landscape, and analysis o more

• Hereditary Angioedema Therapeutics - Pipeline Assessment and Market Forecasts to 2019

  Introduction GlobalData, the industry analysis specialist, has released its new report, “Hereditary Angioedema Therapeutics - Pipeline Assessment and Market Forecasts to 2019”. The report is an essential source of information and analysis on the global Hereditary Angioedema Therapeutics market. The more

Websites Japan