Intermediates

News Intermediates

• Siegfried plans production plant in Nantong, China

  Siegfried plans the erection of a production plant in Nantong, China, supported by NETDA, a Chinese development organization. The development of production capacity in China will strengthen Siegfried’s competitive position and create additional sales opportunities in Asia. The company is exploring f more

• Novasep and instrAction expand alliance to include taxane purification

  Novasep, a leading supplier of manufacturing solutions to the life science industries, and instrAction, a manufacturer of innovative chromatographic stationary phases for API purification processes, announced they have expanded their worldwide strategic alliance to include the purification of taxane more

• Deciphering how CD4 T cells die during HIV infection

  Scientists at Gladstone Institute of Virology and Immunology have solved a long-standing mystery about HIV infection–namely how HIV promotes the death of CD4 T cells. It is the loss of this critical subset of immune cells that leads to the development of AIDS. Most immune cells that die during HIV i more

White papers Intermediates

• Outsourcing to India and China: Cultural diffculties with the perception of costs
  

  Aparna Singh (AS), Program Manager for the Chemicals Materials and Foods team at Frost & Sullivan India, recently caught up with Mr. Steve Fishwick (SF), Projects Group Director, AstraZeneca at the Frost & Sullivan's Global Life Sciences Summit 2006 at Goa, India. He was one of the key speakers at this premium summit. more

• ORAC Assay Performed on the POLARstar Omega and PHERAstar FS microplate reader
  

  In all oxygen consuming cells, metabolism and oxidative stress generate several intermediates and byproducts that are collectively known as reactive oxygen species (ROS). ROS are necessary intermediates in the human body, but they are also involved in the aging process and in the development of many degenerative diseases, including cancer, heart disease, Alzheimer's and Parkinson's. Herein we describe the determination of the antioxidant capacity of different fruit juices using the ORAC assay; a standardized method that uses Trolox®, a water-soluble analogue of vitamin E, as a standard substance more

Publications Intermediates

• TWINKLE is an essential mitochondrial helicase required for synthesis of nascent D-loop strands and complete mtDNA replication

  Replication of the mammalian mitochondrial DNA (mtDNA) is dependent on the minimal replisome, consisting of the heterotrimeric mtDNA polymerase (POLG), the hexameric DNA helicase TWINKLE and the tetrameric single-stranded DNA-binding protein (mtSSB). TWINKLE has been shown to unwind DNA during the more

• Single-molecule DNA repair in live bacteria [Biochemistry]

  Cellular DNA damage is reversed by balanced repair pathways that avoid accumulation of toxic intermediates. Despite their importance, the organization of DNA repair pathways and the function of repair enzymes in vivo have remained unclear because of the inability to directly observe individual react more

• The availability of purine nucleotides regulates natural competence by controlling translation of the competence activator Sxy

  Summary Many bacteria are naturally competent, able to bind and take up DNA from their extracellular environment. This DNA can serve as a significant source of nutrients, in addition to providing genetic material for recombination. The regulation of competence in several model organisms highligh more

Market studies Intermediates

• NGL Fine-chem Ltd. - Strategic SWOT Analysis Review

  NGL Fine-chem Ltd. (NGL) is a publicly held pharmaceutical company. It is principally engaged in the manufacture of pharmaceutical ingredients and intermediate products that are used in animal and human health. The company's products include finished dosage forms, diminazene aceturate granules and h more

• Shilpa Medicare Ltd. (SHILPAMED) - Financial and Strategic SWOT Analysis Review

  Shilpa Medicare Ltd. (SHILPAMED) - Financial and Strategic SWOT Analysis Review Summary Shilpa Medicare Ltd. is a pharmaceuticals manufacturing company. It manufactures and export high-quality Active Pharmaceutical Ingredients Fine Chemicals, intermediates, herbal products and specialty chemical more

• Auro Laboratories Limited - Strategic SWOT Analysis Review

  Auro Laboratories Limited (Auro Laboratories) is pharmaceutical company that is engaged in the manufacturing of active pharmaceutical ingredients (APIs), intermediates and generic formulations. The company principally focuses on the preparation of anti-diabetic drugs. Auro Laboratories manufactures more

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